SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mpx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 4 THR A 577
LEU A 494
VAL A 584
LEU A 427
 None
 0.97A 1fbmD-1mpxA:
undetectable		 1fbmD-1mpxA:
8.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		8 / 8 TYR A  82
ARG A  87
TYR A 123
GLU A 176
GLN A 226
HIS A 340
SER A 341
TYR A 345
 None
 0.33A 1nx9A-1mpxA:
55.7		 1nx9A-1mpxA:
60.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		8 / 8 TYR A  82
ARG A  87
TYR A 123
GLU A 176
GLN A 226
HIS A 340
SER A 341
TYR A 345
 None
 0.32A 1nx9B-1mpxA:
55.8		 1nx9B-1mpxA:
60.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		8 / 8 TYR A  82
ARG A  87
TYR A 123
GLU A 176
GLN A 226
HIS A 340
SER A 341
TYR A 345
 None
 0.32A 1nx9C-1mpxA:
55.7		 1nx9C-1mpxA:
60.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		8 / 8 TYR A  82
ARG A  87
TYR A 123
GLU A 176
GLN A 226
HIS A 340
SER A 341
TYR A 345
 None
 0.31A 1nx9D-1mpxA:
55.7		 1nx9D-1mpxA:
60.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.00A 1o76B-1mpxA:
0.0		 1o76B-1mpxA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.06A 1t85A-1mpxA:
0.0		 1t85A-1mpxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.01A 1t87A-1mpxA:
0.0		 1t87A-1mpxA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 MET A 200
GLN A 284
PHE A 178
ARG A 133
 None
 1.38A 1t9wA-1mpxA:
0.0		 1t9wA-1mpxA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 6 PHE A 372
VAL A 193
LEU A 191
SER A 164
 None
 0.96A 1wrlB-1mpxA:
undetectable		 1wrlB-1mpxA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 GLY A 313
VAL A 181
LEU A 286
LEU A 333
MET A 321
 None
 1.04A 1ya4C-1mpxA:
16.5		 1ya4C-1mpxA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 ARG A 364
LEU A 368
VAL A 193
VAL A 343
 None
 0.96A 2bdmA-1mpxA:
undetectable		 2bdmA-1mpxA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 0.98A 2qbmA-1mpxA:
0.0		 2qbmA-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 11 LEU A 634
LEU A 419
LEU A 421
ILE A 496
THR A 484
 None
 1.25A 2qd3A-1mpxA:
1.8		 2qd3A-1mpxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 9 ILE A 390
ARG A 406
ALA A 403
VAL A 388
 None
 0.95A 2vufB-1mpxA:
0.0		 2vufB-1mpxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.05A 2zwtA-1mpxA:
0.0		 2zwtA-1mpxA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.05A 2zwuA-1mpxA:
0.0		 2zwuA-1mpxA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 11 MET A  54
ILE A  52
ASN A 186
VAL A 115
LEU A  77
 None
None
GOL  A3011 (-4.1A)
None
None
 1.05A 3a51A-1mpxA:
0.0		 3a51A-1mpxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 MET A  54
ILE A  52
ASN A 186
VAL A 115
LEU A  77
 None
None
GOL  A3011 (-4.1A)
None
None
 1.06A 3a51C-1mpxA:
0.0		 3a51C-1mpxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 MET A  54
ILE A  52
ASN A 186
VAL A 115
LEU A  77
 None
None
GOL  A3011 (-4.1A)
None
None
 1.04A 3a51E-1mpxA:
0.0		 3a51E-1mpxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		3 / 3 PRO A 298
LEU A 330
ARG A 327
 None
 0.56A 3aqiA-1mpxA:
undetectable		 3aqiA-1mpxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		3 / 3 PRO A 298
LEU A 330
ARG A 327
 None
 0.79A 3aqiB-1mpxA:
undetectable		 3aqiB-1mpxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 LEU A 191
ALA A 150
ASP A 149
ILE A  52
ILE A 154
 None
 1.03A 3cyxA-1mpxA:
undetectable		 3cyxA-1mpxA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.03A 3fwfB-1mpxA:
0.0		 3fwfB-1mpxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 10 SER A 341
LEU A 368
ILE A 171
SER A 198
GLY A 172
 None
 1.03A 3iluB-1mpxA:
0.1
3iluE-1mpxA:
0.2		 3iluB-1mpxA:
17.70
3iluE-1mpxA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		3 / 3 ARG A 339
LEU A 350
THR A 359
 None
 0.81A 3oxcA-1mpxA:
0.1		 3oxcA-1mpxA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 11 VAL A 388
GLY A 498
ALA A 499
LEU A 401
LEU A 333
 None
 0.64A 3sm2B-1mpxA:
undetectable		 3sm2B-1mpxA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.04A 3wrhA-1mpxA:
0.0		 3wrhA-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.04A 3wrjA-1mpxA:
0.0		 3wrjA-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.04A 3wrlE-1mpxA:
0.0		 3wrlE-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.03A 3wrmF-1mpxA:
0.0		 3wrmF-1mpxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 VAL A 584
TYR A 523
VAL A 486
ILE A 520
 None
 1.08A 4aftD-1mpxA:
0.0
4aftE-1mpxA:
0.0		 4aftD-1mpxA:
17.74
4aftE-1mpxA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 LEU A 634
LEU A 419
LEU A 421
ILE A 496
THR A 484
 None
 1.29A 4f4dA-1mpxA:
0.9		 4f4dA-1mpxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		3 / 3 ASP A 145
ARG A 292
THR A 148
 None
 0.68A 4i13A-1mpxA:
undetectable		 4i13A-1mpxA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 8 ASN A 396
LEU A 538
TYR A 536
LEU A 353
TRP A 398
 None
 1.38A 4jjkA-1mpxA:
2.1		 4jjkA-1mpxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.02A 4l4eA-1mpxA:
0.0		 4l4eA-1mpxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.05A 4l4fA-1mpxA:
0.0		 4l4fA-1mpxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 PHE A 107
THR A  78
VAL A 195
ASP A 104
 None
 1.00A 4l4gA-1mpxA:
0.0		 4l4gA-1mpxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 5 ASP A 145
LEU A 135
ARG A 292
THR A 148
 None
 1.47A 4p3qA-1mpxA:
undetectable		 4p3qA-1mpxA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		3 / 3 ASP A 145
ARG A 292
THR A 148
 None
 0.65A 4p3rA-1mpxA:
undetectable		 4p3rA-1mpxA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 GLN A 303
PRO A 199
ILE A 201
ASP A 207
 None
 1.00A 4w5oA-1mpxA:
3.7		 4w5oA-1mpxA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 9 LEU A 139
GLN A 284
ALA A 279
ASP A 278
ALA A 276
 None
 1.48A 4wnuB-1mpxA:
0.0		 4wnuB-1mpxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 GLN A 303
PRO A 199
ILE A 201
ASP A 207
 None
 1.03A 4z4eA-1mpxA:
3.7		 4z4eA-1mpxA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 7 GLN A 303
PRO A 199
ILE A 201
ASP A 207
 None
 1.01A 4z4gA-1mpxA:
3.7		 4z4gA-1mpxA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 5 GLN A 303
PRO A 199
ILE A 201
ASP A 207
 None
 0.99A 4z4hA-1mpxA:
3.8		 4z4hA-1mpxA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 6 ASP A 501
TYR A 420
PRO A 629
LEU A 421
 None
 1.35A 5bmvB-1mpxA:
3.3		 5bmvB-1mpxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 4 ASP A 514
GLY A 547
ASP A 512
ASP A 614
 None
 1.17A 5e72A-1mpxA:
undetectable		 5e72A-1mpxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 11 ASP A 597
ARG A 546
PHE A 210
PHE A 609
PHE A 220
 None
 1.41A 5hwcA-1mpxA:
undetectable		 5hwcA-1mpxA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 SER A 541
PHE A 578
GLN A 422
LEU A 427
VAL A 586
 None
 1.24A 5tudD-1mpxA:
undetectable		 5tudD-1mpxA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 5 TRP A 404
THR A 573
ASN A 575
LEU A 469
 None
 1.47A 5vkqA-1mpxA:
0.0
5vkqB-1mpxA:
0.0		 5vkqA-1mpxA:
16.87
5vkqB-1mpxA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 5 TRP A 404
THR A 573
ASN A 575
LEU A 469
 None
 1.44A 5vkqB-1mpxA:
0.0
5vkqC-1mpxA:
0.0		 5vkqB-1mpxA:
16.87
5vkqC-1mpxA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 5 TRP A 404
THR A 573
ASN A 575
LEU A 469
 None
 1.43A 5vkqC-1mpxA:
0.0
5vkqD-1mpxA:
0.2		 5vkqC-1mpxA:
16.87
5vkqD-1mpxA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 4 ASN A 575
LEU A 469
TRP A 404
THR A 573
 None
 1.43A 5vkqA-1mpxA:
0.1
5vkqD-1mpxA:
0.2		 5vkqA-1mpxA:
16.87
5vkqD-1mpxA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 8 ALA A 183
THR A 185
THR A 293
ALA A 285
 None
 0.89A 5x2tI-1mpxA:
undetectable
5x2tJ-1mpxA:
undetectable
5x2tK-1mpxA:
undetectable
5x2tL-1mpxA:
undetectable		 5x2tI-1mpxA:
13.17
5x2tJ-1mpxA:
15.80
5x2tK-1mpxA:
13.17
5x2tL-1mpxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 THR A 132
GLU A 309
HIS A 340
ASP A 307
ASP A 208
 None
 1.47A 5ximB-1mpxA:
undetectable		 5ximB-1mpxA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 TRP A 515
SER A 630
GLY A 438
SER A 625
PHE A 485
 None
 1.43A 6a94A-1mpxA:
undetectable		 6a94A-1mpxA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		5 / 12 VAL A 470
PHE A 355
LEU A 302
VAL A 334
GLY A 347
 None
 1.40A 6brdA-1mpxA:
undetectable		 6brdA-1mpxA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 6 GLY A 304
LEU A 305
VAL A 195
PHE A 371
 None
 1.02A 6h7lA-1mpxA:
undetectable		 6h7lA-1mpxA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpx ALPHA-AMINO ACID
ESTER HYDROLASE
(Xanthomonas
citri) 		4 / 6 GLY A 304
LEU A 305
VAL A 195
PHE A 371
 None
 1.03A 6h7lB-1mpxA:
undetectable		 6h7lB-1mpxA:
9.56