SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		5 / 12 ALA A  70
GLY A  39
VAL A  38
VAL A 115
ILE A  85
 None
None
BRD  A 148 (-4.2A)
None
None
 0.89A 2o4lB-1mq0A:
undetectable		 2o4lB-1mq0A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		5 / 9 ARG A 103
ALA A  70
GLY A  39
VAL A 115
ILE A  85
 None
 1.00A 2o4pB-1mq0A:
undetectable		 2o4pB-1mq0A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		5 / 12 ARG A 103
GLY A  39
VAL A  38
VAL A 115
ILE A  85
 None
None
BRD  A 148 (-4.2A)
None
None
 0.85A 3cyxB-1mq0A:
undetectable		 3cyxB-1mq0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		5 / 11 ARG A 103
GLY A  39
VAL A  38
VAL A 115
ILE A  85
 None
None
BRD  A 148 (-4.2A)
None
None
 0.78A 3oxxB-1mq0A:
undetectable		 3oxxB-1mq0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		5 / 11 ARG A 103
GLY A  39
VAL A  38
VAL A 115
ILE A  85
 None
None
BRD  A 148 (-4.2A)
None
None
 0.82A 3oxxD-1mq0A:
undetectable		 3oxxD-1mq0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		4 / 4 ALA A  41
VAL A  20
GLY A 122
THR A 118
 None
 1.09A 4ubeA-1mq0A:
undetectable		 4ubeA-1mq0A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		4 / 5 PHE A 109
ASP A  81
PHE A  82
VAL A  75
 None
 1.12A 5a1rA-1mq0A:
0.0		 5a1rA-1mq0A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 1mq0 CYTIDINE DEAMINASE
(Homo
sapiens) 		4 / 7 ARG A  48
THR A  44
ASP A  81
GLY A  78
 None
 1.07A 5hwaA-1mq0A:
undetectable		 5hwaA-1mq0A:
19.69