SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
1mqt POLYPROTEIN
(Enterovirus
B)
4 / 8 GLU A 127
GLN A 134
HIS A 222
SER A 233
None
1.29A 1nx9A-1mqtA:
undetectable
1nx9A-1mqtA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
1mqt POLYPROTEIN
(Enterovirus
B)
4 / 8 GLU A 127
GLN A 134
HIS A 222
SER A 233
None
1.29A 1nx9B-1mqtA:
undetectable
1nx9B-1mqtA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
1mqt POLYPROTEIN
(Enterovirus
B)
4 / 8 GLU A 127
GLN A 134
HIS A 222
SER A 233
None
1.29A 1nx9C-1mqtA:
undetectable
1nx9C-1mqtA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
1mqt POLYPROTEIN
(Enterovirus
B)
4 / 8 GLU A 127
GLN A 134
HIS A 222
SER A 233
None
1.28A 1nx9D-1mqtA:
2.8
1nx9D-1mqtA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)
1mqt POLYPROTEIN
(Enterovirus
B)
3 / 3 THR A 165
THR A 163
PRO A 167
None
0.86A 1qfiB-1mqtA:
undetectable
1qfiB-1mqtA:
4.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
5 / 12 PRO A  44
GLY C 112
ILE C 168
VAL C 222
SER C 221
None
1.25A 1sg9A-1mqtA:
undetectable
1sg9A-1mqtA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 8 PRO B  56
LEU B  91
GLY B  90
PRO B 247
None
0.94A 1ya4A-1mqtB:
undetectable
1ya4A-1mqtB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
3 / 3 SER A  62
GLU C  48
ASP C 219
None
0.70A 2avdB-1mqtA:
undetectable
2avdB-1mqtA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 ASP C  50
ILE C 168
VAL C  94
None
0.58A 2avvD-1mqtC:
undetectable
2avvD-1mqtC:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 ASN B 217
ILE B 205
MET B 202
None
0.82A 2h42C-1mqtB:
undetectable
2h42C-1mqtB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 LYS C 226
GLY C  90
PRO C  89
None
0.94A 2hreB-1mqtC:
0.0
2hreB-1mqtC:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 8 LEU C 166
LEU C  95
PRO C 142
GLY C 188
None
0.91A 2po5A-1mqtC:
undetectable
2po5A-1mqtC:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 8 LEU C 166
LEU C  95
PRO C 142
GLY C 188
None
0.85A 2po5B-1mqtC:
undetectable
2po5B-1mqtC:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 10 LEU B 221
ALA B 152
VAL B 243
SER B  87
PHE B  82
None
1.13A 2w9gA-1mqtB:
undetectable
2w9gA-1mqtB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 10 LEU B 221
ALA B 152
VAL B 243
SER B  87
PHE B  82
None
1.12A 2w9hA-1mqtB:
undetectable
2w9hA-1mqtB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 12 LEU B 182
PHE A 194
THR A 246
VAL C  40
ILE C  46
None
1.06A 3c6gA-1mqtB:
undetectable
3c6gA-1mqtB:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 11 LEU B 221
ALA B 152
VAL B 243
SER B  87
PHE B  82
None
1.12A 3frbX-1mqtB:
undetectable
3frbX-1mqtB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
3 / 3 GLU A  65
ASP C  18
ASP A 115
None
0.59A 3jb2A-1mqtA:
0.0
3jb2A-1mqtA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 6 THR B 199
GLN B 111
ILE B  16
SER B 197
None
0.86A 3peoG-1mqtB:
undetectable
3peoG-1mqtB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 8 ARG B 193
VAL C 158
VAL C 200
ILE C 198
None
0.99A 3remA-1mqtB:
undetectable
3remA-1mqtB:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 PRO B  53
THR B  54
LEU B 255
None
0.46A 3ttrA-1mqtB:
undetectable
3ttrA-1mqtB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 12 GLN C  81
GLY C  84
PRO C 142
ALA C 139
GLY C 140
None
1.33A 3v3oB-1mqtC:
undetectable
3v3oB-1mqtC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 THR C  58
ASN C  56
GLU C  59
None
0.77A 3v4tA-1mqtC:
0.0
3v4tC-1mqtC:
0.0
3v4tA-1mqtC:
18.87
3v4tC-1mqtC:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)
1mqt POLYPROTEIN
(Enterovirus
B)
5 / 12 THR A 246
SER A 192
TYR A 191
ASP A 115
PHE A 114
None
None
SPL  A 284 ( 3.9A)
None
SPL  A 284 (-4.9A)
1.24A 3vw1D-1mqtA:
undetectable
3vw1D-1mqtA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 7 LEU C 104
ALA C  47
VAL C  40
ILE C 103
None
0.91A 3wsjB-1mqtC:
undetectable
3wsjB-1mqtC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
3 / 3 ARG B 215
TRP A 198
GLY A 197
None
1.04A 4e7cA-1mqtB:
undetectable
4e7cA-1mqtB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 PHE B 226
VAL B 110
ILE B 241
None
0.62A 4emaA-1mqtB:
undetectable
4emaA-1mqtB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)
1mqt POLYPROTEIN
(Enterovirus
B)
3 / 3 HIS A 222
TRP A 161
SER A 124
None
1.23A 4lrhD-1mqtA:
undetectable
4lrhD-1mqtA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 PRO B 203
MET B 202
TYR B  35
None
1.08A 4qa0B-1mqtB:
undetectable
4qa0B-1mqtB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
3 / 3 PRO B 203
MET B 202
TYR B  35
None
1.04A 4qa0A-1mqtB:
undetectable
4qa0A-1mqtB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 8 PHE A 114
ASP C  18
ASP C  17
TYR A 238
SPL  A 284 (-4.9A)
None
None
None
1.21A 4qb9D-1mqtA:
0.0
4qb9D-1mqtA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 7 PRO C  37
SER B 207
GLU B 129
THR A 211
None
1.30A 4uacA-1mqtC:
undetectable
4uacA-1mqtC:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
6 / 12 PHE C 220
LEU C 100
GLY C 187
THR A 282
VAL C  53
PHE C  85
None
1.39A 4wnwA-1mqtC:
0.0
4wnwA-1mqtC:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
3 / 3 ASP B  84
ASN B  88
PHE A 201
None
0.93A 5jglB-1mqtB:
undetectable
5jglB-1mqtB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 7 VAL C  53
PHE C  85
LEU C 116
THR C 117
None
0.94A 5m78A-1mqtC:
0.0
5m78A-1mqtC:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B;
Enterovirus
B)
5 / 12 LEU B 123
VAL C  52
LEU A 254
THR B 183
THR A 271
None
1.15A 6b54A-1mqtB:
undetectable
6b54A-1mqtB:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 10 PHE C  85
THR C  88
GLY C 188
ILE C 190
ILE C 114
None
1.25A 6ebpB-1mqtC:
undetectable
6ebpB-1mqtC:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 10 PHE C  85
LEU C  95
THR C  88
GLY C 188
ILE C 114
None
1.07A 6ebpC-1mqtC:
undetectable
6ebpC-1mqtC:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
5 / 10 PHE C  85
LEU C  95
THR C  88
GLY C 188
ILE C 114
None
1.05A 6ebpD-1mqtC:
undetectable
6ebpD-1mqtC:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
4 / 6 ASN C 218
VAL A  43
VAL A  18
THR A  17
None
1.04A 6f32B-1mqtC:
undetectable
6f32B-1mqtC:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 6 GLY C 101
LEU C 104
PHE C  85
PHE C  83
None
0.98A 6h7lA-1mqtC:
undetectable
6h7lA-1mqtC:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)
1mqt POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B)
4 / 6 GLY C 101
LEU C 104
PHE C  85
PHE C  83
None
0.98A 6h7lB-1mqtC:
undetectable
6h7lB-1mqtC:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
4 / 4 ASP C 157
ILE A  28
PRO A  29
LEU A  31
None
1.11A 6mkeB-1mqtC:
0.0
6mkeB-1mqtC:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus
B;
Enterovirus
B)
4 / 4 ASP C 157
ILE A  28
PRO A  29
LEU A  31
None
1.17A 6mkeA-1mqtC:
0.0
6mkeA-1mqtC:
14.54