SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		5 / 11 SER A  40
VAL A  37
ILE A  96
LEU A 102
LEU A  26
 None
 1.21A 2a15A-1mqvA:
undetectable		 2a15A-1mqvA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 8 ASP A 118
LYS A 114
PHE A  82
ASP A  80
 None
None
HEM  A 150 (-3.4A)
None
 0.93A 2aouA-1mqvA:
undetectable		 2aouA-1mqvA:
17.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 5 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.82A 2yldA-1mqvA:
14.8		 2yldA-1mqvA:
36.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 5 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.90A 2ylgA-1mqvA:
14.9		 2ylgA-1mqvA:
36.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 8 ILE A  22
LEU A 110
ALA A  89
ALA A  88
 None
 0.69A 3r9tA-1mqvA:
undetectable		 3r9tA-1mqvA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 7 ILE A  22
LEU A 110
ALA A  89
ALA A  88
 None
 0.74A 3r9tB-1mqvA:
undetectable		 3r9tB-1mqvA:
22.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 5 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.83A 3zwiA-1mqvA:
14.8		 3zwiA-1mqvA:
36.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		5 / 9 ALA A  45
ALA A  86
LEU A  51
SER A  40
LEU A  41
 None
 1.35A 4or0A-1mqvA:
2.8		 4or0A-1mqvA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		5 / 9 ALA A  89
THR A  90
ALA A  86
ILE A  22
ASP A  47
 None
 1.19A 4qvqK-1mqvA:
undetectable
4qvqL-1mqvA:
undetectable		 4qvqK-1mqvA:
20.75
4qvqL-1mqvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		5 / 9 ALA A  89
THR A  90
ALA A  86
ILE A  22
ASP A  47
 None
 1.19A 4qvqY-1mqvA:
undetectable
4qvqZ-1mqvA:
undetectable		 4qvqY-1mqvA:
20.75
4qvqZ-1mqvA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 5 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.84A 5jliA-1mqvA:
14.8		 5jliA-1mqvA:
36.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JRA_A_ASCA202_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 4 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.86A 5jraA-1mqvA:
14.7		 5jraA-1mqvA:
35.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		4 / 5 GLY A 111
CYH A 113
LYS A 114
HIS A 117
 None
HEM  A 150 (-1.9A)
None
HEM  A 150 (-3.3A)
 0.83A 5jt4A-1mqvA:
14.8		 5jt4A-1mqvA:
35.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		5 / 9 ALA A  18
LEU A 110
ILE A 106
ILE A  96
ALA A  43
 None
 0.67A 5nunA-1mqvA:
undetectable		 5nunA-1mqvA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1mqv CYTOCHROME C'
(Rhodopseudomonas
palustris) 		3 / 3 PHE A  78
ASP A  74
LYS A  77
 HEM  A 150 (-4.5A)
None
None
 0.89A 6awtD-1mqvA:
undetectable		 6awtD-1mqvA:
24.68