SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mt0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		5 / 12 ALA A 670
LYS A 493
ILE A 681
LEU A 490
ILE A 500
 None
 1.33A 1d1gA-1mt0A:
undetectable		 1d1gA-1mt0A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 499
ALA A 670
THR A 666
ILE A 674
GLN A 684
 None
 1.13A 1nt2A-1mt0A:
undetectable		 1nt2A-1mt0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		3 / 3 ILE A 658
ILE A 500
THR A 656
 None
 0.60A 1rg7A-1mt0A:
undetectable		 1rg7A-1mt0A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 4 GLY A 502
SER A 506
VAL A 682
LEU A 701
 None
SO4  A 708 (-3.0A)
None
None
 1.17A 1yajB-1mt0A:
undetectable		 1yajB-1mt0A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 4 TYR A 698
LEU A 701
LEU A 664
HIS A 687
 None
 1.44A 2x7hB-1mt0A:
undetectable		 2x7hB-1mt0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 4 ASP A 486
GLY A 679
LYS A 680
GLU A 677
 None
 1.44A 3hznD-1mt0A:
undetectable		 3hznD-1mt0A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 6 TYR A 519
PHE A 475
PRO A 521
LEU A 485
 None
 1.37A 3tgvB-1mt0A:
0.0		 3tgvB-1mt0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 6 TYR A 519
PHE A 475
PRO A 521
LEU A 485
 None
 1.33A 3tgvD-1mt0A:
0.0		 3tgvD-1mt0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 5 HIS A 662
GLN A 705
SER A 665
VAL A 667
 None
 1.03A 4a99D-1mt0A:
1.0		 4a99D-1mt0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		5 / 11 MET A 648
GLY A 583
ALA A 617
LEU A 620
LEU A 533
 None
 1.04A 4kt0A-1mt0A:
undetectable
4kt0J-1mt0A:
0.0		 4kt0A-1mt0A:
14.78
4kt0J-1mt0A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 672
GLY A 499
GLU A 496
SER A 506
 None
None
None
SO4  A 708 (-3.0A)
 1.23A 4z3oA-1mt0A:
undetectable
4z3oB-1mt0A:
undetectable		 4z3oA-1mt0A:
17.80
4z3oB-1mt0A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 5 ALA A 661
ARG A 663
ALA A 632
GLU A 641
 None
 1.36A 5a06C-1mt0A:
undetectable
5a06D-1mt0A:
undetectable		 5a06C-1mt0A:
19.01
5a06D-1mt0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 5 SER A 634
ARG A 503
GLY A 502
GLU A 677
 None
 1.12A 5cdqA-1mt0A:
undetectable
5cdqB-1mt0A:
undetectable
5cdqC-1mt0A:
undetectable		 5cdqA-1mt0A:
23.97
5cdqB-1mt0A:
22.05
5cdqC-1mt0A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 679
ASP A 630
ILE A 515
TYR A 477
 None
 1.01A 5iwuA-1mt0A:
0.0		 5iwuA-1mt0A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		5 / 8 ILE A 588
LEU A 591
ILE A 559
ILE A 614
SER A 640
 None
 1.15A 5numA-1mt0A:
undetectable		 5numA-1mt0A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 629
ILE A 644
MET A 645
ASN A 647
 None
 1.27A 6dhbA-1mt0A:
0.0		 6dhbA-1mt0A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		4 / 6 MET A 648
GLY A 583
ALA A 617
LEU A 620
 None
 0.98A 6fosA-1mt0A:
undetectable		 6fosA-1mt0A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN
(Escherichia
coli) 		5 / 10 MET A 648
GLY A 583
ALA A 617
LEU A 620
LEU A 533
 None
 1.10A 6hqbA-1mt0A:
undetectable
6hqbJ-1mt0A:
undetectable		 6hqbA-1mt0A:
18.67
6hqbJ-1mt0A:
9.54