SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		5 / 12 ILE A 407
ALA A 345
LEU A 533
PRO A 499
ILE A 402
 None
 0.99A 1dhjB-1mv5A:
undetectable		 1dhjB-1mv5A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		4 / 6 ILE A 402
ARG A 530
THR A 532
LEU A 533
 None
 0.97A 2einN-1mv5A:
0.0
2einW-1mv5A:
0.0		 2einN-1mv5A:
19.88
2einW-1mv5A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		4 / 6 ARG A 497
ILE A 407
GLN A 394
GLU A 413
 None
 1.45A 2ya7C-1mv5A:
undetectable		 2ya7C-1mv5A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		4 / 8 SER A 387
PHE A 386
VAL A 422
LEU A 502
 None
 1.13A 3jq7C-1mv5A:
undetectable		 3jq7C-1mv5A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		4 / 8 ILE A 385
ARG A 391
ILE A 400
MET A 503
 None
 0.97A 4xtaB-1mv5A:
undetectable		 4xtaB-1mv5A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		5 / 10 ILE A 372
MET A 503
VAL A 348
ILE A 551
PRO A 395
 None
 0.95A 5ienB-1mv5A:
0.0		 5ienB-1mv5A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mv5 MULTIDRUG RESISTANCE
ABC TRANSPORTER
ATP-BINDING AND
PERMEASE PROTEIN
(Lactococcus
lactis) 		4 / 8 ILE A 385
PHE A 374
ARG A 346
LEU A 343
 None
 0.96A 5zcoA-1mv5A:
0.0
5zcoJ-1mv5A:
0.0		 5zcoA-1mv5A:
19.88
5zcoJ-1mv5A:
16.16