SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_C_MTXC164_2 (DIHYDROFOLATE REDUCTASE)	1mvf	IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION (Camelus dromedarius)	4 / 4	ILE A 53 ARG A 19 ILE A 51 THR A 28	None	0.99A	3ia4C-1mvfA: undetectable	3ia4C-1mvfA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RP8_C_ASCC501_0 (ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA)	1mvf	IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION (Camelus dromedarius)	5 / 12	ILE A 53 GLN A 72 ILE A 59 ALA A 107 ILE A 70	None	1.10A	4rp8C-1mvfA: undetectable	4rp8C-1mvfA: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1mvf	IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION (Camelus dromedarius)	4 / 7	ALA A 92 THR A 91 VAL A 122 GLU A 89	None	0.76A	5ecmD-1mvfA: undetectable	5ecmD-1mvfA: 12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1mvf	IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION (Camelus dromedarius)	4 / 7	ALA A 92 THR A 91 VAL A 122 GLU A 89	None	0.82A	5ecoD-1mvfA: 0.0	5ecoD-1mvfA: 12.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IA4_C_MTXC164_2","DIHYDROFOLATE REDUCTASE","1mvf","IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION","Camelus dromedarius",4,"ILE A  53;ARG A  19;ILE A  51;THR A  28","None","0.99A","3ia4C-1mvfA:undetectable","3ia4C-1mvfA:20.56"],["4RP8_C_ASCC501_0","ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA","1mvf","IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION","Camelus dromedarius",5,"ILE A  53;GLN A  72;ILE A  59;ALA A 107;ILE A  70","None","1.10A","4rp8C-1mvfA:undetectable","4rp8C-1mvfA:15.04"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1mvf","IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION","Camelus dromedarius",4,"ALA A  92;THR A  91;VAL A 122;GLU A  89","None","0.76A","5ecmD-1mvfA:undetectable","5ecmD-1mvfA:12.72"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1mvf","IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION","Camelus dromedarius",4,"ALA A  92;THR A  91;VAL A 122;GLU A  89","None","0.82A","5ecoD-1mvfA:0.0","5ecoD-1mvfA:12.72"]]