SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LEU A 433
PHE A 383
LEU A 385
LEU A 245
VAL A 249
None
1.39A 2qd4A-1mvhA:
undetectable
2qd4A-1mvhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LEU A 433
PHE A 383
LEU A 385
LEU A 245
VAL A 249
None
1.32A 2qd4B-1mvhA:
undetectable
2qd4B-1mvhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OOI_A_SAMA237_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.52A 3ooiA-1mvhA:
17.5
3ooiA-1mvhA:
27.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OPE_A_SAMA7_0
(PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.49A 3opeA-1mvhA:
15.6
3opeA-1mvhA:
30.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
3 / 3 PHE A 449
TYR A 381
TYR A 357
None
0.92A 4ffwA-1mvhA:
undetectable
4ffwA-1mvhA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 TYR A 451
VAL A 396
GLY A 359
LEU A 385
SER A 420
None
1.41A 4or0A-1mvhA:
undetectable
4or0A-1mvhA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 TYR A 451
VAL A 396
GLY A 359
LEU A 385
SER A 420
None
1.43A 4ot2A-1mvhA:
undetectable
4ot2A-1mvhA:
18.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YNM_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.50A 4ynmB-1mvhA:
15.7
4ynmB-1mvhA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YNP_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 10 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.66A 4ynpB-1mvhA:
15.7
4ynpB-1mvhA:
30.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_A_SAMA3004_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.40A 4ypaA-1mvhA:
16.2
4ypaA-1mvhA:
29.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_A_SAMA3004_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TYR A 381
ASN A 409
HIS A 410
None
1.12A 4ypaA-1mvhA:
16.2
4ypaA-1mvhA:
29.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TRP A 340
ASN A 409
HIS A 410
None
1.03A 4ypaB-1mvhA:
15.9
4ypaB-1mvhA:
29.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_C_SAMC2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TRP A 340
ASN A 409
HIS A 410
None
1.05A 4ypaC-1mvhA:
16.2
4ypaC-1mvhA:
29.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_D_SAMD2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
6 / 12 LYS A 338
GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
1.03A 4ypaD-1mvhA:
16.3
4ypaD-1mvhA:
29.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YPE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.45A 4ypeA-1mvhA:
15.8
4ypeA-1mvhA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YPE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TYR A 381
ASN A 409
HIS A 410
None
1.10A 4ypeA-1mvhA:
15.8
4ypeA-1mvhA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YPE_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.49A 4ypeB-1mvhA:
15.7
4ypeB-1mvhA:
30.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPU_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.38A 4ypuA-1mvhA:
16.1
4ypuA-1mvhA:
29.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPU_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 LYS A 338
GLY A 339
TRP A 340
ASN A 409
HIS A 410
None
0.93A 4ypuB-1mvhA:
16.0
4ypuB-1mvhA:
29.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPU_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 LYS A 338
GLY A 339
TYR A 381
ASN A 409
HIS A 410
None
1.07A 4ypuB-1mvhA:
16.0
4ypuB-1mvhA:
29.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
3 / 3 ASP A 377
ASN A 373
PHE A 237
None
0.93A 5jglB-1mvhA:
undetectable
5jglB-1mvhA:
21.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHN_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.44A 5jhnA-1mvhA:
15.2
5jhnA-1mvhA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.43A 5jhnB-1mvhA:
24.4
5jhnB-1mvhA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JIY_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.40A 5jiyA-1mvhA:
24.5
5jiyA-1mvhA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JIY_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.40A 5jiyB-1mvhA:
24.5
5jiyB-1mvhA:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T0K_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.40A 5t0kA-1mvhA:
24.6
5t0kA-1mvhA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T0M_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.41A 5t0mB-1mvhA:
24.6
5t0mB-1mvhA:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TEG_B_SAMB401_0
(HISTONE H4 MUTANT
PEPTIDE WITH
H4K20NORLEUCINE
N-LYSINE
METHYLTRANSFERASE
KMT5A)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 10 LYS A 338
GLY A 339
TYR A 381
ASN A 409
HIS A 410
None
1.00A 5tegB-1mvhA:
11.7
5tegE-1mvhA:
undetectable
5tegB-1mvhA:
21.07
5tegE-1mvhA:
4.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TTF_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.47A 5ttfA-1mvhA:
24.5
5ttfA-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.41A 5ttfB-1mvhA:
24.3
5ttfB-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TTF_D_SAMD1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.50A 5ttfD-1mvhA:
15.1
5ttfD-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TTG_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.46A 5ttgA-1mvhA:
7.2
5ttgA-1mvhA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TTG_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.48A 5ttgB-1mvhA:
15.0
5ttgB-1mvhA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUY_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.43A 5tuyA-1mvhA:
24.9
5tuyA-1mvhA:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUY_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.42A 5tuyB-1mvhA:
15.1
5tuyB-1mvhA:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUZ_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.48A 5tuzB-1mvhA:
15.1
5tuzB-1mvhA:
36.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UPD_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.41A 5updA-1mvhA:
17.4
5updA-1mvhA:
27.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V21_A_SAMA1804_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.54A 5v21A-1mvhA:
16.0
5v21A-1mvhA:
30.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V21_A_SAMA1804_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TYR A 381
ASN A 409
HIS A 410
None
1.15A 5v21A-1mvhA:
16.0
5v21A-1mvhA:
30.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.48A 5v9iA-1mvhA:
24.3
5v9iA-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V9I_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.44A 5v9iB-1mvhA:
24.2
5v9iB-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V9I_C_SAMC1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.49A 5v9iC-1mvhA:
24.2
5v9iC-1mvhA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V9J_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.50A 5v9jA-1mvhA:
15.4
5v9jA-1mvhA:
37.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V9J_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.49A 5v9jB-1mvhA:
24.8
5v9jB-1mvhA:
37.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
3 / 3 ARG A 295
PHE A 435
LEU A 328
None
0.77A 5veuA-1mvhA:
undetectable
5veuA-1mvhA:
20.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSC_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.46A 5vscA-1mvhA:
24.4
5vscA-1mvhA:
36.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSC_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.47A 5vscB-1mvhA:
14.9
5vscB-1mvhA:
36.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSD_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.50A 5vsdB-1mvhA:
15.4
5vsdB-1mvhA:
36.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSE_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.44A 5vseA-1mvhA:
24.5
5vseA-1mvhA:
36.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSE_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.45A 5vseB-1mvhA:
24.3
5vseB-1mvhA:
36.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VSF_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.46A 5vsfB-1mvhA:
15.4
5vsfB-1mvhA:
36.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
4 / 5 ILE A 354
PHE A 408
ARG A 343
THR A 222
None
1.20A 5z84N-1mvhA:
undetectable
5z84W-1mvhA:
0.0
5z84N-1mvhA:
18.42
5z84W-1mvhA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5M_A_SAMA805_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH6)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.69A 6a5mA-1mvhA:
22.2
6a5mA-1mvhA:
27.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 LYS A 338
GLY A 339
TRP A 340
TYR A 381
HIS A 410
None
0.88A 6bp4B-1mvhA:
34.9
6bp4B-1mvhA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CEN_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 11 GLY A 339
TRP A 340
TYR A 381
ASN A 409
HIS A 410
None
0.40A 6cenA-1mvhA:
17.6
6cenA-1mvhA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
5 / 12 TRP A 340
TYR A 381
PHE A 407
ASN A 409
HIS A 410
None
0.76A 6chgC-1mvhA:
6.7
6chgC-1mvhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)
1mvh CRYPTIC LOCI
REGULATOR 4

(Schizosaccharomy
ces
pombe)
3 / 3 ASP A 389
ASP A 281
ASN A 319
None
0.86A 6gngB-1mvhA:
undetectable
6gngB-1mvhA:
18.36