SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mvl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 10 ALA A  50
LEU A  23
LEU A  89
GLU A  77
GLU A  75
None
1.24A 1a29A-1mvlA:
undetectable
1a29A-1mvlA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 10 LEU A  23
ALA A  25
LEU A 122
LEU A 121
LEU A 135
None
1.11A 1gwrA-1mvlA:
0.0
1gwrA-1mvlA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
3 / 3 TRP A  96
THR A  70
TYR A  72
None
1.17A 2a3aA-1mvlA:
undetectable
2a3aA-1mvlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
3 / 3 TRP A  96
THR A  70
TYR A  72
None
1.22A 2a3aB-1mvlA:
undetectable
2a3aB-1mvlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
3 / 3 TRP A  96
THR A  70
TYR A  72
None
1.17A 2a3bA-1mvlA:
undetectable
2a3bA-1mvlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
4 / 6 LEU A  38
LEU A  24
PRO A  66
VAL A  69
None
1.14A 2dqyC-1mvlA:
1.5
2dqyC-1mvlA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 12 LEU A  23
ALA A  25
LEU A 122
LEU A 121
LEU A 135
None
1.03A 3hm1A-1mvlA:
undetectable
3hm1A-1mvlA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 12 LEU A  23
ALA A  25
LEU A 122
LEU A 121
LEU A 135
None
1.06A 3q95A-1mvlA:
undetectable
3q95A-1mvlA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
3 / 3 LYS A 133
PRO A 134
LEU A 135
None
0.74A 3tpxE-1mvlA:
0.0
3tpxE-1mvlA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 11 LEU A  23
ALA A  25
LEU A 122
LEU A 121
LEU A 135
None
1.09A 3uudA-1mvlA:
0.0
3uudA-1mvlA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 8 ALA A 184
ILE A 189
ALA A  32
PHE A  35
LEU A  38
None
1.20A 4v1fA-1mvlA:
undetectable
4v1fB-1mvlA:
undetectable
4v1fA-1mvlA:
18.18
4v1fB-1mvlA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
5 / 10 LEU A  23
ALA A  25
LEU A 122
LEU A 121
LEU A 135
None
1.08A 5hyrA-1mvlA:
0.0
5hyrA-1mvlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)
1mvl PPC DECARBOXYLASE
ATHAL3A

(Arabidopsis
thaliana)
4 / 5 ILE A 189
LEU A  65
GLY A  36
PHE A  35
None
0.95A 5kmdC-1mvlA:
undetectable
5kmdD-1mvlA:
undetectable
5kmdC-1mvlA:
22.60
5kmdD-1mvlA:
22.60