SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1mvo PHOP RESPONSE
REGULATOR
(Bacillus
subtilis) 		3 / 3 LEU A  80
LEU A  49
PHE A 105
 None
 0.61A 2pgrA-1mvoA:
undetectable		 2pgrA-1mvoA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1mvo PHOP RESPONSE
REGULATOR
(Bacillus
subtilis) 		4 / 8 ILE A  62
LEU A  91
ALA A  97
MET A  79
 None
 0.75A 3r9tA-1mvoA:
undetectable		 3r9tA-1mvoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1mvo PHOP RESPONSE
REGULATOR
(Bacillus
subtilis) 		4 / 7 LEU A  78
ASP A  98
ALA A  97
TYR A 100
 None
NA  A 202 (-2.8A)
None
None
 1.11A 3rodD-1mvoA:
undetectable		 3rodD-1mvoA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1mvo PHOP RESPONSE
REGULATOR
(Bacillus
subtilis) 		4 / 8 PHE A  87
GLY A  92
LEU A  95
ILE A  77
 None
None
None
NA  A 202 ( 4.6A)
 0.80A 4em2A-1mvoA:
0.0		 4em2A-1mvoA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1mvo PHOP RESPONSE
REGULATOR
(Bacillus
subtilis) 		5 / 12 GLY A  92
MET A  79
TYR A 100
GLU A  94
ILE A  62
 None
 1.26A 4fglA-1mvoA:
6.6
4fglB-1mvoA:
5.0		 4fglA-1mvoA:
21.89
4fglB-1mvoA:
21.89