SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 12 SER A 130
PHE A 131
LEU A  73
LEU A  92
LEU A  96
 None
 1.37A 1e7wA-1mw5A:
undetectable		 1e7wA-1mw5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 ILE A 135
LEU A  62
PHE A 131
THR A  32
LEU A  34
 None
 1.26A 1v55N-1mw5A:
undetectable
1v55W-1mw5A:
undetectable		 1v55N-1mw5A:
15.69
1v55W-1mw5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 SER A 130
PHE A 131
LEU A  73
LEU A  92
LEU A  96
 None
 1.37A 2bfpB-1mw5A:
undetectable		 2bfpB-1mw5A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 ILE A 135
LEU A  62
PHE A 131
THR A  32
LEU A  34
 None
 1.27A 3abkA-1mw5A:
0.0
3abkJ-1mw5A:
undetectable		 3abkA-1mw5A:
15.69
3abkJ-1mw5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 ILE A 135
LEU A  62
PHE A 131
THR A  32
LEU A  34
 None
 1.32A 3abmN-1mw5A:
undetectable
3abmW-1mw5A:
undetectable		 3abmN-1mw5A:
15.69
3abmW-1mw5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 ILE A 135
LEU A  62
PHE A 131
THR A  32
LEU A  34
 None
 1.26A 3asoN-1mw5A:
0.0
3asoW-1mw5A:
undetectable		 3asoN-1mw5A:
15.69
3asoW-1mw5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		3 / 3 ALA A  79
VAL A  80
GLN A  54
 None
 0.73A 3of4B-1mw5A:
0.0		 3of4B-1mw5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		4 / 7 GLU A 112
TYR A 146
LEU A 144
PHE A 123
 None
 1.21A 4twdF-1mw5A:
undetectable
4twdJ-1mw5A:
undetectable		 4twdF-1mw5A:
20.71
4twdJ-1mw5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		5 / 8 ILE A 135
LEU A  62
PHE A 131
THR A  32
LEU A  34
 None
 1.31A 5zcpN-1mw5A:
0.0
5zcpW-1mw5A:
undetectable		 5zcpN-1mw5A:
15.69
5zcpW-1mw5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1mw5 HYPOTHETICAL PROTEIN
HI1480
(Haemophilus
influenzae) 		4 / 7 VAL A 103
ILE A 109
ARG A 134
ALA A 143
 None
 0.77A 6hd6B-1mw5A:
undetectable		 6hd6B-1mw5A:
16.48