SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		5 / 12 ILE A 174
LEU A 194
PHE A 189
LEU A 185
LEU A 163
 None
 1.18A 1dtlA-1mw7A:
0.6		 1dtlA-1mw7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		4 / 5 ILE A 209
PRO A 208
PHE A 131
ILE A  93
 None
 1.12A 2hjhA-1mw7A:
undetectable		 2hjhA-1mw7A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		4 / 6 LEU A 109
SER A 111
PHE A 113
ILE A 226
 None
 0.89A 3ko0B-1mw7A:
undetectable		 3ko0B-1mw7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		4 / 6 LEU A 109
SER A 111
PHE A 113
ILE A 226
 None
 0.86A 3ko0S-1mw7A:
undetectable		 3ko0S-1mw7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		4 / 7 ASN A 186
LEU A 194
LEU A  52
PHE A 182
 None
 1.16A 3nk2X-1mw7A:
0.0		 3nk2X-1mw7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		5 / 12 LEU A  92
THR A 237
GLY A  85
ILE A 209
ASN A  88
 None
 1.08A 3nk7A-1mw7A:
undetectable		 3nk7A-1mw7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		5 / 10 LEU A 211
ALA A  87
PHE A  89
GLY A  90
ILE A 209
 None
 1.02A 3qpsA-1mw7A:
undetectable		 3qpsA-1mw7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		5 / 9 LEU A 185
ILE A 204
GLU A 165
PHE A 137
VAL A 136
 None
 1.14A 3tmzA-1mw7A:
0.1		 3tmzA-1mw7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		4 / 4 ASN A  88
ALA A  87
GLY A 118
THR A 116
 None
 1.09A 4bboC-1mw7A:
0.0		 4bboC-1mw7A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		5 / 12 ALA A 119
GLY A 118
ILE A 121
GLY A  85
ARG A 225
 None
 1.13A 4obwD-1mw7A:
undetectable		 4obwD-1mw7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 1mw7 HYPOTHETICAL PROTEIN
HP0162
(Helicobacter
pylori) 		3 / 3 ARG A 104
THR A  99
ASP A 231
 None
 0.87A 5g5gA-1mw7A:
0.3
5g5gB-1mw7A:
0.0		 5g5gA-1mw7A:
22.10
5g5gB-1mw7A:
23.10