SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1mwi	G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (Escherichia coli)	5 / 12	GLY A 143 LEU A 138 ILE A 41 ASN A 140 LEU A 107	None	0.88A	2nxeA-1mwiA: undetectable	2nxeA-1mwiA: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HUO_A_PNNA303_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	1mwi	G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (Escherichia coli)	4 / 4	GLN A 110 GLN A 114 GLY A 115 HIS A 86	None	1.18A	3huoA-1mwiA: 0.0	3huoA-1mwiA: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_1 (METHYLTRANSFERASE NSUN4)	1mwi	G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (Escherichia coli)	3 / 3	ASP A 48 ARG A 49 ASP A 61	None	0.66A	4fp9D-1mwiA: undetectable	4fp9D-1mwiA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_A_BRLA501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1mwi	G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (Escherichia coli)	4 / 5	GLY A 65 LEU A 159 ILE A 41 LEU A 107	None	0.83A	4o8fA-1mwiA: 0.0	4o8fA-1mwiA: 21.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1mwi","G\/U MISMATCH-SPECIFIC DNA GLYCOSYLASE","Escherichia coli",5,"GLY A 143;LEU A 138;ILE A  41;ASN A 140;LEU A 107","None","0.88A","2nxeA-1mwiA:undetectable","2nxeA-1mwiA:22.05"],["3HUO_A_PNNA303_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","1mwi","G\/U MISMATCH-SPECIFIC DNA GLYCOSYLASE","Escherichia coli",4,"GLN A 110;GLN A 114;GLY A 115;HIS A  86","None","1.18A","3huoA-1mwiA:0.0","3huoA-1mwiA:21.93"],["4FP9_D_SAMD401_1","METHYLTRANSFERASE NSUN4","1mwi","G\/U MISMATCH-SPECIFIC DNA GLYCOSYLASE","Escherichia coli",3,"ASP A  48;ARG A  49;ASP A  61","None","0.66A","4fp9D-1mwiA:undetectable","4fp9D-1mwiA:17.78"],["4O8F_A_BRLA501_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1mwi","G\/U MISMATCH-SPECIFIC DNA GLYCOSYLASE","Escherichia coli",4,"GLY A  65;LEU A 159;ILE A  41;LEU A 107","None","0.83A","4o8fA-1mwiA:0.0","4o8fA-1mwiA:21.05"]]