SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1my7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_B_ACTB401_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14)	1my7	NF-KAPPAB P65 (RELA) SUBUNIT (Mus musculus)	4 / 6	GLU A 225 ARG A 236 ARG A 274 ARG A 273	None	1.28A	5l6eA-1my7A: undetectable 5l6eB-1my7A: undetectable	5l6eA-1my7A: 20.09 5l6eB-1my7A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G501_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	1my7	NF-KAPPAB P65 (RELA) SUBUNIT (Mus musculus)	4 / 7	ILE A 196 VAL A 226 ILE A 212 THR A 254	None	0.93A	6cduF-1my7A: 3.1 6cduG-1my7A: 1.9	6cduF-1my7A: 15.74 6cduG-1my7A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_G_EY4G502_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	1my7	NF-KAPPAB P65 (RELA) SUBUNIT (Mus musculus)	4 / 8	ILE A 196 VAL A 226 ILE A 212 THR A 254	None	0.85A	6cduG-1my7A: 1.9 6cduH-1my7A: 2.1	6cduG-1my7A: 15.74 6cduH-1my7A: 15.74