SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.60A 1a4gA-1mz5A:
24.1		 1a4gA-1mz5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.57A 1a4gB-1mz5A:
23.9		 1a4gB-1mz5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 11 ALA A 442
ILE A 606
LEU A 621
LEU A 608
GLY A 422
 None
 0.90A 1b02A-1mz5A:
0.0		 1b02A-1mz5A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_1
(DIHYDROFOLATE
REDUCTASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 4 GLU A  29
ASN A  24
ARG A  88
THR A  17
 None
NAG  A 652 (-1.8A)
None
None
 1.38A 1drfA-1mz5A:
0.0		 1drfA-1mz5A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 8 ALA A 221
ILE A 197
PRO A 232
ILE A 243
ILE A 208
 None
 1.42A 1hshD-1mz5A:
undetectable		 1hshD-1mz5A:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.63A 1nncA-1mz5A:
20.1		 1nncA-1mz5A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 10 PHE A 372
VAL A 331
GLY A 332
THR A 304
HIS A 357
 None
 1.14A 1pwyE-1mz5A:
undetectable		 1pwyE-1mz5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 11 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.28A 1q23F-1mz5A:
undetectable		 1q23F-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 10 PHE A 372
VAL A 331
GLY A 332
THR A 304
HIS A 357
 None
 1.03A 1v3qE-1mz5A:
undetectable		 1v3qE-1mz5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 5 SER A  58
GLU A 358
TYR A 343
ASP A 363
 None
 1.32A 1vidA-1mz5A:
0.0		 1vidA-1mz5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A  58
GLU A 358
TYR A 343
ASP A 363
 None
 1.32A 2cl5B-1mz5A:
0.0		 2cl5B-1mz5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.63A 2cmlA-1mz5A:
5.0		 2cmlA-1mz5A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.62A 2cmlB-1mz5A:
20.5		 2cmlB-1mz5A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.65A 2cmlC-1mz5A:
20.5		 2cmlC-1mz5A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.67A 2cmlD-1mz5A:
20.4		 2cmlD-1mz5A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
MET A  96
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.40A 2f0zA-1mz5A:
38.1		 2f0zA-1mz5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		8 / 12 ARG A  36
ILE A  37
ARG A  54
MET A  96
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.60A 2f10A-1mz5A:
37.3		 2f10A-1mz5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 VAL A 346
LEU A 318
PHE A 303
HIS A 305
 None
 1.34A 2f8dA-1mz5A:
0.0		 2f8dA-1mz5A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.77A 2htqA-1mz5A:
11.4		 2htqA-1mz5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 9 LEU A 550
GLY A 557
GLY A 570
SER A 518
LEU A 528
 None
 1.03A 2qmmA-1mz5A:
undetectable		 2qmmA-1mz5A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 11 LEU A 550
GLY A 557
GLY A 570
SER A 518
LEU A 528
 None
 1.01A 2qmmA-1mz5A:
undetectable
2qmmB-1mz5A:
undetectable		 2qmmA-1mz5A:
16.14
2qmmB-1mz5A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLY A 505
HIS A 584
GLU A 507
GLY A 508
LEU A 514
 None
 1.04A 2x1lB-1mz5A:
undetectable		 2x1lB-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 VAL A 467
TYR A 476
ARG A 474
GLY A 269
 None
 0.82A 2y05A-1mz5A:
undetectable
2y05B-1mz5A:
undetectable		 2y05A-1mz5A:
21.45
2y05B-1mz5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ASP A  52
ASP A  97
ARG A 246
ARG A 315
TYR A 343
 None
 0.47A 2ya7A-1mz5A:
40.3		 2ya7A-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ILE A  37
ASP A  52
ILE A  64
ARG A 315
TYR A 343
 None
 1.40A 2ya7A-1mz5A:
40.3		 2ya7A-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ASP A  52
ASP A  97
ARG A 246
ARG A 315
TYR A 343
 None
 0.45A 2ya7B-1mz5A:
40.3		 2ya7B-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ILE A  37
ASP A  52
ILE A  64
ARG A 315
TYR A 343
 None
 1.38A 2ya7B-1mz5A:
40.3		 2ya7B-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ASP A  52
ASP A  97
ARG A 246
ARG A 315
TYR A 343
 None
 0.47A 2ya7C-1mz5A:
35.7		 2ya7C-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
ILE A  37
ASP A  52
ILE A  64
ARG A 315
 None
 1.41A 2ya7C-1mz5A:
35.7		 2ya7C-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ASP A  52
ASP A  97
ARG A 246
ARG A 315
TYR A 343
 None
 0.44A 2ya7D-1mz5A:
39.9		 2ya7D-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ILE A  37
ASP A  52
ILE A  64
ARG A 315
TYR A 343
 None
 1.38A 2ya7D-1mz5A:
39.9		 2ya7D-1mz5A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 8 GLY A 419
ASN A 610
ILE A 242
VAL A 274
 None
 0.86A 2yoeB-1mz5A:
0.0
2yoeC-1mz5A:
0.0		 2yoeB-1mz5A:
19.75
2yoeC-1mz5A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A  58
GLU A 358
TYR A 343
ASP A 363
 None
 1.27A 2zvjA-1mz5A:
0.0		 2zvjA-1mz5A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.72A 3b7eA-1mz5A:
20.6		 3b7eA-1mz5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.71A 3b7eB-1mz5A:
20.5		 3b7eB-1mz5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLU A 358
GLY A 342
SER A 335
GLN A 333
ARG A 317
 None
 1.18A 3bwyA-1mz5A:
undetectable		 3bwyA-1mz5A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLY A 503
GLY A 516
LEU A 501
LEU A 485
LEU A 608
 None
 1.01A 3cjtO-1mz5A:
undetectable		 3cjtO-1mz5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 LEU A 107
GLY A 137
GLY A 155
VAL A 158
LEU A 134
 None
 0.92A 3cjtO-1mz5A:
undetectable		 3cjtO-1mz5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.58A 3ckzA-1mz5A:
6.5		 3ckzA-1mz5A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 THR A  39
VAL A  48
THR A  50
VAL A  68
 None
 0.50A 3em0B-1mz5A:
1.3		 3em0B-1mz5A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ALA A 442
ILE A 606
LEU A 621
LEU A 608
GLY A 422
 None
 0.95A 3k2hA-1mz5A:
undetectable		 3k2hA-1mz5A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ALA A 442
ILE A 606
LEU A 621
LEU A 608
GLY A 422
 None
 0.96A 3k2hB-1mz5A:
0.0		 3k2hB-1mz5A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
 None
 0.70A 3k37B-1mz5A:
24.1		 3k37B-1mz5A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
TYR A 343
 None
 0.50A 3k39B-1mz5A:
24.1		 3k39B-1mz5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 SER A 599
GLY A 589
SER A 518
 None
 0.69A 3loqA-1mz5A:
undetectable		 3loqA-1mz5A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 PRO A 533
SER A 535
ASN A 571
 None
 0.85A 3lslG-1mz5A:
undetectable		 3lslG-1mz5A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 SER A   6
SER A   5
HIS A 357
 None
 0.68A 3mzeA-1mz5A:
2.4		 3mzeA-1mz5A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLY A 503
GLY A 505
LEU A 528
THR A 484
LEU A 550
 None
 1.06A 3p2kA-1mz5A:
undetectable		 3p2kA-1mz5A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLY A 503
GLY A 505
LEU A 528
THR A 484
LEU A 550
 None
 1.08A 3p2kB-1mz5A:
undetectable		 3p2kB-1mz5A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.59A 3sanA-1mz5A:
21.4		 3sanA-1mz5A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.60A 3sanB-1mz5A:
11.5		 3sanB-1mz5A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.66A 3ti5A-1mz5A:
11.4		 3ti5A-1mz5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.67A 3ti5B-1mz5A:
20.6		 3ti5B-1mz5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.61A 3ticA-1mz5A:
20.4		 3ticA-1mz5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.65A 3ticB-1mz5A:
20.6		 3ticB-1mz5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.62A 3ticC-1mz5A:
20.4		 3ticC-1mz5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.62A 3ticD-1mz5A:
20.6		 3ticD-1mz5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.17A 3u9fB-1mz5A:
0.0
3u9fC-1mz5A:
0.0		 3u9fB-1mz5A:
17.19
3u9fC-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 10 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.16A 3u9fE-1mz5A:
undetectable		 3u9fE-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.16A 3u9fH-1mz5A:
0.0
3u9fI-1mz5A:
0.0		 3u9fH-1mz5A:
17.19
3u9fI-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.19A 3u9fJ-1mz5A:
undetectable
3u9fK-1mz5A:
undetectable		 3u9fJ-1mz5A:
17.19
3u9fK-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 10 THR A  66
PHE A  11
LEU A 107
VAL A  43
VAL A 100
 None
 1.22A 3u9fK-1mz5A:
0.0		 3u9fK-1mz5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.70A 4b7nA-1mz5A:
11.5		 4b7nA-1mz5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.74A 4b7qA-1mz5A:
11.0		 4b7qA-1mz5A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.73A 4b7qB-1mz5A:
20.7		 4b7qB-1mz5A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.68A 4b7qC-1mz5A:
11.5		 4b7qC-1mz5A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.73A 4b7qD-1mz5A:
20.8		 4b7qD-1mz5A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.71A 4cpnA-1mz5A:
8.2		 4cpnA-1mz5A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.70A 4cpnB-1mz5A:
7.9		 4cpnB-1mz5A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.59A 4cpzA-1mz5A:
7.9		 4cpzA-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.55A 4cpzB-1mz5A:
7.9		 4cpzB-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.68A 4cpzC-1mz5A:
24.0		 4cpzC-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.48A 4cpzD-1mz5A:
24.2		 4cpzD-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.72A 4cpzE-1mz5A:
24.1		 4cpzE-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.74A 4cpzF-1mz5A:
23.9		 4cpzF-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.64A 4cpzG-1mz5A:
5.3		 4cpzG-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.72A 4cpzH-1mz5A:
24.2		 4cpzH-1mz5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 ASP A  60
ASP A  97
ASP A 248
GLU A 358
 None
 1.15A 4feuB-1mz5A:
2.2		 4feuB-1mz5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 ASP A  60
ASP A  97
ASP A 248
GLU A 358
 None
 1.18A 4fevD-1mz5A:
undetectable		 4fevD-1mz5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 8 ASP A  60
ASP A  97
ASP A 248
GLU A 358
 None
 1.20A 4fewF-1mz5A:
0.0		 4fewF-1mz5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.64A 4i00A-1mz5A:
11.3		 4i00A-1mz5A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 CYH A 229
ASN A 250
LYS A 226
 None
 1.07A 4k50A-1mz5A:
0.0		 4k50A-1mz5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 GLN A 326
THR A 270
LEU A 271
THR A 304
 None
 1.09A 4mbsA-1mz5A:
0.0		 4mbsA-1mz5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.57A 4mwrA-1mz5A:
20.2		 4mwrA-1mz5A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 315
TYR A 343
 None
 0.66A 4mwxA-1mz5A:
20.2		 4mwxA-1mz5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 ARG A  36
ASP A  60
ARG A 315
 None
 0.54A 4mx0A-1mz5A:
20.7		 4mx0A-1mz5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.83A 4wa5A-1mz5A:
11.6		 4wa5A-1mz5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 PHE A  35
THR A  80
VAL A  32
PHE A  20
 None
 0.98A 4wnvD-1mz5A:
undetectable		 4wnvD-1mz5A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 PHE A 372
SER A 345
LEU A 347
LEU A 353
 None
 1.32A 5dzke-1mz5A:
undetectable
5dzks-1mz5A:
undetectable		 5dzke-1mz5A:
16.33
5dzks-1mz5A:
1.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 ASN A 119
ASP A 126
GLY A 127
 None
 0.46A 5fctB-1mz5A:
undetectable		 5fctB-1mz5A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 5 SER A  58
GLU A 358
TYR A 343
ASP A 363
 None
 1.31A 5fhrA-1mz5A:
0.0		 5fhrA-1mz5A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 10 ASP A 214
ALA A 183
ILE A 101
TYR A 108
GLY A 189
 None
 1.17A 5i6xA-1mz5A:
undetectable		 5i6xA-1mz5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 PHE A  35
VAL A  32
TYR A  55
ILE A  82
 None
 1.30A 5iwuA-1mz5A:
1.1		 5iwuA-1mz5A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ASP A  60
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.62A 5l17A-1mz5A:
20.2		 5l17A-1mz5A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 VAL A 603
ILE A 606
VAL A 548
ALA A 487
 None
 0.52A 5ospA-1mz5A:
0.5		 5ospA-1mz5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 7 VAL A 603
ILE A 606
VAL A 548
ALA A 487
 None
 0.54A 5osrA-1mz5A:
0.3		 5osrA-1mz5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.14A 5x7pA-1mz5A:
6.9		 5x7pA-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.19A 5x7pB-1mz5A:
6.9		 5x7pB-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.18A 5x7qA-1mz5A:
5.7		 5x7qA-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		4 / 6 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.17A 5x7rA-1mz5A:
6.8		 5x7rA-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 9 ASP A 214
ALA A 183
ILE A 101
GLY A 189
SER A 211
 None
 1.22A 6awoA-1mz5A:
undetectable		 6awoA-1mz5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 9 ASP A 214
ALA A 183
ILE A 101
GLY A 189
SER A 211
 None
 1.23A 6awqA-1mz5A:
undetectable		 6awqA-1mz5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 GLY A 104
VAL A  48
ILE A 152
GLY A 137
VAL A 136
 None
 0.96A 6dh6A-1mz5A:
undetectable		 6dh6A-1mz5A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ILE A  37
ARG A  54
ARG A 246
ASP A 248
TYR A 343
 None
 1.05A 6ekuA-1mz5A:
38.7		 6ekuA-1mz5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ARG A  54
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.54A 6ekuA-1mz5A:
38.7		 6ekuA-1mz5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		6 / 12 ARG A  36
ILE A  37
ASP A  97
ARG A 246
ASP A 248
TYR A 343
 None
 1.20A 6ekuA-1mz5A:
38.7		 6ekuA-1mz5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		7 / 12 ARG A  36
ILE A  37
ASP A  97
GLU A 231
ARG A 246
ARG A 315
TYR A 343
 None
 0.79A 6ekuA-1mz5A:
38.7		 6ekuA-1mz5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		3 / 3 LEU A 501
ASN A 605
LEU A 485
 None
 0.70A 6exiA-1mz5A:
undetectable		 6exiA-1mz5A:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 1mz5 SIALIDASE
(Trypanosoma
rangeli) 		5 / 12 ARG A  36
ASP A  60
ARG A 246
ARG A 315
TYR A 343
 None
 0.66A 6hcxA-1mz5A:
20.2		 6hcxA-1mz5A:
8.50