SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A 142
GLY A 193
GLY A 196
ARG A 149
ASP A 145
 None
 1.05A 2b25A-1mzaA:
undetectable		 2b25A-1mzaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
LEU A  53
 None
 1.42A 3elwA-1mzaA:
undetectable		 3elwA-1mzaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 1.03A 3gczA-1mzaA:
undetectable		 3gczA-1mzaA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.87A 3p97C-1mzaA:
undetectable		 3p97C-1mzaA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		4 / 4 GLY A  44
GLY A 197
THR A 139
LEU A 155
 None
 0.93A 3si7C-1mzaA:
undetectable
3si7D-1mzaA:
undetectable		 3si7C-1mzaA:
19.39
3si7D-1mzaA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.86A 5e9qC-1mzaA:
undetectable		 5e9qC-1mzaA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.88A 5ec8C-1mzaA:
undetectable		 5ec8C-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.94A 5ehiA-1mzaA:
undetectable		 5ehiA-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.84A 5ehiC-1mzaA:
undetectable		 5ehiC-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.85A 5eifC-1mzaA:
undetectable		 5eifC-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.92A 5eiwA-1mzaA:
undetectable		 5eiwA-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.97A 5ekxA-1mzaA:
undetectable		 5ekxA-1mzaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.96A 5kqrA-1mzaA:
undetectable		 5kqrA-1mzaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.92A 5kqsA-1mzaA:
undetectable		 5kqsA-1mzaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.92A 5m5bA-1mzaA:
undetectable		 5m5bA-1mzaA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		3 / 3 ALA A  55
GLN A  99
THR A 229
 None
 0.72A 5n0oA-1mzaA:
undetectable		 5n0oA-1mzaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.89A 5njvA-1mzaA:
undetectable		 5njvA-1mzaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		5 / 12 GLY A  44
GLY A 142
GLY A 193
GLY A 196
ASP A 145
 None
 0.89A 5wz1B-1mzaA:
undetectable		 5wz1B-1mzaA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1mza PRO-GRANZYME K
(Homo
sapiens) 		4 / 8 GLY A  43
THR A  54
TRP A 141
TYR A  35
 None
 0.97A 6eqpA-1mzaA:
undetectable		 6eqpA-1mzaA:
17.22