SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_A_NCAA1501_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1mzu	PPR (Rhodospirillum centenum)	4 / 7	PHE A 98 ALA A 67 ARG A 52 ASP A 97	HC4 A 130 (-4.9A) HC4 A 130 (-3.4A) HC4 A 130 ( 3.9A) None	1.00A	2e5dA-1mzuA: undetectable 2e5dB-1mzuA: undetectable	2e5dA-1mzuA: 12.55 2e5dB-1mzuA: 12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_B_NCAB1502_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1mzu	PPR (Rhodospirillum centenum)	4 / 7	ASP A 97 PHE A 98 ALA A 67 ARG A 52	None HC4 A 130 (-4.9A) HC4 A 130 (-3.4A) HC4 A 130 ( 3.9A)	1.00A	2e5dA-1mzuA: undetectable 2e5dB-1mzuA: undetectable	2e5dA-1mzuA: 12.55 2e5dB-1mzuA: 12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1mzu	PPR (Rhodospirillum centenum)	5 / 7	TYR A 42 ILE A 31 ASP A 34 GLY A 37 PHE A 62	HC4 A 130 (-4.6A) None None None None	1.49A	4iqqA-1mzuA: undetectable	4iqqA-1mzuA: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1mzu	PPR (Rhodospirillum centenum)	5 / 8	TYR A 42 ILE A 31 ASP A 34 GLY A 37 PHE A 62	HC4 A 130 (-4.6A) None None None None	1.49A	4iqqD-1mzuA: undetectable	4iqqD-1mzuA: 17.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2E5D_A_NCAA1501_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","1mzu","PPR","Rhodospirillum centenum",4,"PHE A  98;ALA A  67;ARG A  52;ASP A  97","HC4 A 130 (-4.9A);HC4 A 130 (-3.4A);HC4 A 130 ( 3.9A);None","1.00A","2e5dA-1mzuA:undetectable;2e5dB-1mzuA:undetectable","2e5dA-1mzuA:12.55;2e5dB-1mzuA:12.55"],["2E5D_B_NCAB1502_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","1mzu","PPR","Rhodospirillum centenum",4,"ASP A  97;PHE A  98;ALA A  67;ARG A  52","None;HC4 A 130 (-4.9A);HC4 A 130 (-3.4A);HC4 A 130 ( 3.9A)","1.00A","2e5dA-1mzuA:undetectable;2e5dB-1mzuA:undetectable","2e5dA-1mzuA:12.55;2e5dB-1mzuA:12.55"],["4IQQ_A_D16A402_1","THYMIDYLATE SYNTHASE","1mzu","PPR","Rhodospirillum centenum",5,"TYR A  42;ILE A  31;ASP A  34;GLY A  37;PHE A  62","HC4 A 130 (-4.6A);None;None;None;None","1.49A","4iqqA-1mzuA:undetectable","4iqqA-1mzuA:17.32"],["4IQQ_D_D16D402_1","THYMIDYLATE SYNTHASE","1mzu","PPR","Rhodospirillum centenum",5,"TYR A  42;ILE A  31;ASP A  34;GLY A  37;PHE A  62","HC4 A 130 (-4.6A);None;None;None;None","1.49A","4iqqD-1mzuA:undetectable","4iqqD-1mzuA:17.32"]]