SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		4 / 5 LYS A 131
LEU A 124
GLU A 134
ALA A 127
 None
FMN  A 165 (-4.0A)
None
None
 1.10A 1eta1-1n07A:
0.0		 1eta1-1n07A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		4 / 5 LYS A 131
LEU A 124
GLU A 134
ALA A 127
 None
FMN  A 165 (-4.0A)
None
None
 1.17A 1eta2-1n07A:
0.0		 1eta2-1n07A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		4 / 6 LYS A 131
LEU A 124
GLU A 134
ALA A 127
 None
FMN  A 165 (-4.0A)
None
None
 1.12A 1etb1-1n07A:
0.0		 1etb1-1n07A:
22.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		8 / 9 THR A  45
VAL A  79
SER A  81
GLU A  96
ARG A 121
LEU A 132
ILE A 136
ASP A 139
 FMN  A 165 (-4.4A)
FMN  A 165 ( 4.3A)
FMN  A 165 (-3.6A)
FMN  A 165 ( 2.8A)
FMN  A 165 (-2.9A)
FMN  A 165 (-4.5A)
FMN  A 165 ( 4.4A)
FMN  A 165 (-4.7A)
 0.83A 1nb9A-1n07A:
22.3		 1nb9A-1n07A:
42.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		8 / 11 THR A  45
VAL A  64
VAL A  79
GLU A  96
ARG A 121
LEU A 132
ILE A 136
ASP A 139
 FMN  A 165 (-4.4A)
FMN  A 165 (-4.3A)
FMN  A 165 ( 4.3A)
FMN  A 165 ( 2.8A)
FMN  A 165 (-2.9A)
FMN  A 165 (-4.5A)
FMN  A 165 ( 4.4A)
FMN  A 165 (-4.7A)
 0.66A 1t6zA-1n07A:
8.5		 1t6zA-1n07A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		8 / 11 THR A  45
VAL A  64
VAL A  79
GLU A  96
ARG A 121
LEU A 132
ILE A 136
ASP A 139
 FMN  A 165 (-4.4A)
FMN  A 165 (-4.3A)
FMN  A 165 ( 4.3A)
FMN  A 165 ( 2.8A)
FMN  A 165 (-2.9A)
FMN  A 165 (-4.5A)
FMN  A 165 ( 4.4A)
FMN  A 165 (-4.7A)
 0.64A 1t6zB-1n07A:
9.0		 1t6zB-1n07A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1n07 PUTATIVE RIBOFLAVIN
KINASE
(Schizosaccharomy
ces
pombe) 		5 / 12 VAL A  97
ALA A  69
PHE A 161
GLY A 118
LEU A 117
 None
 1.15A 5m54E-1n07A:
undetectable		 5m54E-1n07A:
16.74