SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n0e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		5 / 12 PRO A 115
ALA A  45
LEU A  47
ALA A  49
ILE A  55
 None
 1.17A 2jjpA-1n0eA:
undetectable		 2jjpA-1n0eA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		4 / 8 ASN A  58
ILE A  97
TYR A  76
ARG A  68
 None
 1.00A 3ccfB-1n0eA:
undetectable		 3ccfB-1n0eA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		4 / 8 ASN A  58
PHE A  61
TYR A  76
ARG A  68
 None
 1.50A 3ccfB-1n0eA:
undetectable		 3ccfB-1n0eA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		3 / 3 ARG A  68
HIS A 136
TYR A  76
 None
 1.10A 4fu8A-1n0eA:
undetectable		 4fu8A-1n0eA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		3 / 3 ARG A  68
HIS A 136
TYR A  76
 None
 1.05A 4fu9A-1n0eA:
undetectable		 4fu9A-1n0eA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		4 / 5 LEU A  43
GLY A 110
ILE A  55
LYS A  69
 None
 1.17A 4ma8C-1n0eA:
0.0		 4ma8C-1n0eA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1n0e PROTEIN MRAZ
(Mycoplasma
pneumoniae) 		3 / 3 LEU A  96
PHE A  61
ILE A  97
 None
 0.71A 5dzk1-1n0eA:
undetectable
5dzkF-1n0eA:
0.0
5dzkM-1n0eA:
0.0		 5dzk1-1n0eA:
7.14
5dzkF-1n0eA:
26.43
5dzkM-1n0eA:
20.77