SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_A_356A901_1 (DIPEPTIDYL PEPTIDASE 4)	1n0s	BILIN-BINDING PROTEIN (Pieris brassicae)	5 / 12	TRP A 27 SER A 132 TYR A 109 VAL A 130 VAL A 29	None	1.30A	2rguA-1n0sA: undetectable	2rguA-1n0sA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_B_356B902_1 (DIPEPTIDYL PEPTIDASE 4)	1n0s	BILIN-BINDING PROTEIN (Pieris brassicae)	5 / 11	TRP A 27 SER A 132 TYR A 109 VAL A 130 VAL A 29	None	1.35A	2rguB-1n0sA: undetectable	2rguB-1n0sA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP6_A_B40A601_1 (TRANSPORTER)	1n0s	BILIN-BINDING PROTEIN (Pieris brassicae)	4 / 5	ASP A 164 VAL A 61 ASP A 60 GLY A 43	None	1.19A	4xp6A-1n0sA: undetectable	4xp6A-1n0sA: 15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPL_B_PA1B605_1 (LIPID A EXPORT ATP-BINDING/PERMEASE PROTEIN MSBA)	1n0s	BILIN-BINDING PROTEIN (Pieris brassicae)	3 / 3	ARG A 58 ARG A 116 ARG A 88	FLU A 500 (-3.6A) None None	1.08A	6bplA-1n0sA: undetectable 6bplB-1n0sA: undetectable	6bplA-1n0sA: 18.30 6bplB-1n0sA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6PAH_A_DAHA600_1 (PHENYLALANINE 4-MONOOXYGENASE)	1n0s	BILIN-BINDING PROTEIN (Pieris brassicae)	4 / 6	PRO A 9 HIS A 124 HIS A 4 TYR A 32	None	1.05A	6pahA-1n0sA: undetectable	6pahA-1n0sA: 20.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RGU_A_356A901_1","DIPEPTIDYL PEPTIDASE 4","1n0s","BILIN-BINDING PROTEIN","Pieris brassicae",5,"TRP A  27;SER A 132;TYR A 109;VAL A 130;VAL A  29","None","1.30A","2rguA-1n0sA:undetectable","2rguA-1n0sA:14.19"],["2RGU_B_356B902_1","DIPEPTIDYL PEPTIDASE 4","1n0s","BILIN-BINDING PROTEIN","Pieris brassicae",5,"TRP A  27;SER A 132;TYR A 109;VAL A 130;VAL A  29","None","1.35A","2rguB-1n0sA:undetectable","2rguB-1n0sA:14.19"],["4XP6_A_B40A601_1","TRANSPORTER","1n0s","BILIN-BINDING PROTEIN","Pieris brassicae",4,"ASP A 164;VAL A  61;ASP A  60;GLY A  43","None","1.19A","4xp6A-1n0sA:undetectable","4xp6A-1n0sA:15.75"],["6BPL_B_PA1B605_1","LIPID A EXPORT ATP-BINDING\/PERMEASE PROTEIN MSBA;LIPID A EXPORT ATP-BINDING\/PERMEASE PROTEIN MSBA","1n0s","BILIN-BINDING PROTEIN","Pieris brassicae",3,"ARG A  58;ARG A 116;ARG A  88","FLU A 500 (-3.6A);None;None","1.08A","6bplA-1n0sA:undetectable;6bplB-1n0sA:undetectable","6bplA-1n0sA:18.30;6bplB-1n0sA:18.30"],["6PAH_A_DAHA600_1","PHENYLALANINE 4-MONOOXYGENASE","1n0s","BILIN-BINDING PROTEIN","Pieris brassicae",4,"PRO A   9;HIS A 124;HIS A   4;TYR A  32","None","1.05A","6pahA-1n0sA:undetectable","6pahA-1n0sA:20.75"]]