SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		5 / 12 PHE A1106
VAL A1090
VAL A1138
ARG A1137
GLY A1069
 None
 0.90A 2cbrA-1n10A:
undetectable		 2cbrA-1n10A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		3 / 3 ASP A1178
THR A1202
PRO A1203
 None
 0.71A 2pynB-1n10A:
undetectable		 2pynB-1n10A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		3 / 3 ASP A1178
THR A1202
PRO A1203
 None
 0.68A 2qakB-1n10A:
undetectable		 2qakB-1n10A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		3 / 3 SER A1085
GLU A1075
ASP A1017
 None
 0.64A 2zulA-1n10A:
undetectable		 2zulA-1n10A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		3 / 3 SER A1085
GLU A1075
ASP A1017
 None
 0.62A 3dmhA-1n10A:
undetectable		 3dmhA-1n10A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		4 / 6 THR A1061
ASN A1060
GLY A1059
ASP A1096
 None
 1.35A 3w9tE-1n10A:
undetectable		 3w9tE-1n10A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		3 / 3 LYS A1221
ARG A1213
TRP A1187
 None
 0.83A 4i90A-1n10A:
undetectable		 4i90A-1n10A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1n10 POLLEN ALLERGEN PHL
P 1
(Phleum
pratense) 		5 / 12 HIS A1111
GLY A1110
GLU A1087
ALA A1128
ILE A1076
 None
 1.23A 5igyA-1n10A:
undetectable		 5igyA-1n10A:
19.94