SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 1n1c TORA SPECIFIC
CHAPERONE
(Shewanella
massilia) 		3 / 3 ALA A 199
VAL A 194
TRP A 193
 None
 0.99A 1c4dA-1n1cA:
undetectable
1c4dB-1n1cA:
undetectable		 1c4dA-1n1cA:
11.71
1c4dB-1n1cA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1n1c TORA SPECIFIC
CHAPERONE
(Shewanella
massilia) 		5 / 12 LEU A 159
LEU A 167
ALA A 185
ALA A 187
VAL A 163
 None
 1.32A 1kt4A-1n1cA:
undetectable		 1kt4A-1n1cA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1n1c TORA SPECIFIC
CHAPERONE
(Shewanella
massilia) 		5 / 11 LEU A 159
LEU A 167
ALA A 185
VAL A 163
LEU A 140
 None
 1.45A 1kt6A-1n1cA:
undetectable		 1kt6A-1n1cA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1n1c TORA SPECIFIC
CHAPERONE
(Shewanella
massilia) 		4 / 7 ILE A 198
ILE A 171
LEU A 156
LEU A 140
 None
 0.98A 3adxA-1n1cA:
0.0		 3adxA-1n1cA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1n1c TORA SPECIFIC
CHAPERONE
(Shewanella
massilia) 		4 / 6 ILE A 171
THR A 175
VAL A 163
ASP A 134
 None
 1.02A 4iaqA-1n1cA:
2.8		 4iaqA-1n1cA:
18.67