SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		5 / 10 SER A  99
VAL A 100
LEU A  27
HIS A  56
GLU A  52
 None
 1.12A 1equA-1n1qA:
undetectable		 1equA-1n1qA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 6 LYS A  45
LEU A  49
THR A  41
LEU A  27
 None
 1.10A 1etb2-1n1qA:
undetectable		 1etb2-1n1qA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 8 VAL A 100
LEU A  27
HIS A  56
GLU A  52
 None
 1.03A 1jtvA-1n1qA:
undetectable		 1jtvA-1n1qA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		3 / 3 THR A  59
LEU A  60
LEU A  12
 None
 0.61A 1mz9C-1n1qA:
undetectable		 1mz9C-1n1qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 4 LEU A  23
SER A  99
LEU A 137
LEU A 107
 None
 1.13A 1yajA-1n1qA:
undetectable		 1yajA-1n1qA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 5 LEU A  23
SER A  99
LEU A 137
LEU A 107
 None
 1.12A 1yajD-1n1qA:
undetectable		 1yajD-1n1qA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 8 LEU A  12
VAL A  17
LEU A  60
MET A 129
 None
 0.98A 4r38B-1n1qA:
undetectable		 4r38B-1n1qA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1n1q DPS PROTEIN
(Brevibacillus
brevis) 		4 / 6 ASP A 131
ASP A 106
ARG A  15
ASN A  19
 None
 1.13A 5l6eA-1n1qA:
undetectable		 5l6eA-1n1qA:
18.23