SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 THR A 130
ILE A  88
GLY A  87
ILE A 134
ALA A  54
 None
 0.98A 1vq1B-1n2fA:
undetectable		 1vq1B-1n2fA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PRO A  77
ALA A  78
ALA A 118
ALA A 115
MET A 108
 None
 1.22A 2x2nA-1n2fA:
undetectable		 2x2nA-1n2fA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PRO A  77
ALA A  78
ALA A 119
ALA A 115
MET A 108
 None
 1.09A 2x2nA-1n2fA:
undetectable		 2x2nA-1n2fA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLU A  50
PHE A  95
GLY A  94
ARG A  18
GLY A  40
 None
 1.14A 3jzjA-1n2fA:
undetectable		 3jzjA-1n2fA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvlK-1n2fA:
undetectable
4qvlL-1n2fA:
undetectable		 4qvlK-1n2fA:
23.08
4qvlL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvlY-1n2fA:
undetectable
4qvlZ-1n2fA:
undetectable		 4qvlY-1n2fA:
23.08
4qvlZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvmK-1n2fA:
undetectable
4qvmL-1n2fA:
undetectable		 4qvmK-1n2fA:
23.08
4qvmL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvmY-1n2fA:
undetectable
4qvmZ-1n2fA:
undetectable		 4qvmY-1n2fA:
23.08
4qvmZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.01A 4qvpK-1n2fA:
undetectable
4qvpL-1n2fA:
undetectable		 4qvpK-1n2fA:
23.08
4qvpL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.01A 4qvpY-1n2fA:
undetectable
4qvpZ-1n2fA:
undetectable		 4qvpY-1n2fA:
23.08
4qvpZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvwK-1n2fA:
undetectable
4qvwL-1n2fA:
undetectable		 4qvwK-1n2fA:
22.62
4qvwL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qvwY-1n2fA:
undetectable
4qvwZ-1n2fA:
undetectable		 4qvwY-1n2fA:
22.62
4qvwZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.01A 4qw1K-1n2fA:
undetectable
4qw1L-1n2fA:
undetectable		 4qw1K-1n2fA:
21.82
4qw1L-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.00A 4qw1Y-1n2fA:
undetectable
4qw1Z-1n2fA:
undetectable		 4qw1Y-1n2fA:
21.82
4qw1Z-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qw3K-1n2fA:
undetectable
4qw3L-1n2fA:
undetectable		 4qw3K-1n2fA:
22.73
4qw3L-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 4qw3Y-1n2fA:
undetectable
4qw3Z-1n2fA:
undetectable		 4qw3Y-1n2fA:
22.73
4qw3Z-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 5bxnK-1n2fA:
undetectable
5bxnL-1n2fA:
undetectable		 5bxnK-1n2fA:
23.08
5bxnL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.02A 5bxnY-1n2fA:
undetectable
5bxnZ-1n2fA:
undetectable		 5bxnY-1n2fA:
23.08
5bxnZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.03A 5d0xK-1n2fA:
undetectable
5d0xL-1n2fA:
undetectable		 5d0xK-1n2fA:
23.08
5d0xL-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  22
THR A  13
ALA A  12
GLY A  16
GLY A  17
 None
 1.03A 5d0xY-1n2fA:
undetectable
5d0xZ-1n2fA:
undetectable		 5d0xY-1n2fA:
23.08
5d0xZ-1n2fA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1n2f ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  44
GLY A  87
ILE A  88
GLY A  40
GLY A  41
 None
 0.95A 5koxA-1n2fA:
undetectable		 5koxA-1n2fA:
16.47