SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		6 / 12 GLY A 105
GLY A 220
ILE A  88
LEU A  33
VAL A  47
ALA A 217
 GLC  A 253 ( 3.8A)
GLC  A 253 (-3.1A)
None
None
None
None
 1.42A 1v2xA-1n3pA:
undetectable		 1v2xA-1n3pA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 PRO A 113
GLY A 105
GLY A 104
GLY A 102
GLN A 222
 None
GLC  A 253 ( 3.8A)
None
None
FRU  A 254 (-4.7A)
 1.23A 1wg8A-1n3pA:
undetectable		 1wg8A-1n3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.28A 2y69C-1n3pA:
undetectable
2y69J-1n3pA:
0.0		 2y69C-1n3pA:
20.47
2y69J-1n3pA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.25A 3abmC-1n3pA:
undetectable
3abmJ-1n3pA:
0.0		 3abmC-1n3pA:
20.47
3abmJ-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.29A 3abmP-1n3pA:
undetectable
3abmW-1n3pA:
0.0		 3abmP-1n3pA:
20.47
3abmW-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.23A 3ag3C-1n3pA:
undetectable
3ag3J-1n3pA:
0.0		 3ag3C-1n3pA:
20.47
3ag3J-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 8 LEU A  51
GLY A  48
ALA A  24
ILE A  88
ILE A  50
 None
 1.14A 3ekpA-1n3pA:
undetectable		 3ekpA-1n3pA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 11 GLY A 105
PHE A 111
ASP A  86
ALA A  85
ALA A  44
 GLC  A 253 ( 3.8A)
None
GLC  A 253 (-2.7A)
GLC  A 253 ( 3.7A)
None
 1.11A 3g88A-1n3pA:
0.0		 3g88A-1n3pA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 11 GLY A 105
PHE A 111
ASP A  86
ALA A  85
ALA A  44
 GLC  A 253 ( 3.8A)
None
GLC  A 253 (-2.7A)
GLC  A 253 ( 3.7A)
None
 1.11A 3g88B-1n3pA:
undetectable		 3g88B-1n3pA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 7 PHE A  73
PHE A 215
PHE A  69
SER A  71
 None
 1.47A 3hggA-1n3pA:
undetectable		 3hggA-1n3pA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 6 HIS A 146
VAL A 185
ILE A 154
LEU A 183
 MN  A 271 (-3.5A)
None
None
None
 0.82A 3kk6A-1n3pA:
undetectable		 3kk6A-1n3pA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		6 / 12 LEU A 108
GLY A 105
GLY A 220
ILE A  88
LEU A  33
VAL A  47
 None
GLC  A 253 ( 3.8A)
GLC  A 253 (-3.1A)
None
None
None
 1.46A 3nk7B-1n3pA:
undetectable		 3nk7B-1n3pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 ILE A  92
LEU A  18
PHE A  91
VAL A  31
LEU A  33
 None
 1.08A 3w67B-1n3pA:
undetectable		 3w67B-1n3pA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 VAL A 172
SER A  71
PHE A 215
ILE A  50
LEU A  33
 None
 1.19A 3w67D-1n3pA:
undetectable		 3w67D-1n3pA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 ILE A 154
ARG A  49
GLU A 128
VAL A 157
 None
None
MN  A 271 (-2.8A)
None
 1.27A 4nkxD-1n3pA:
undetectable		 4nkxD-1n3pA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 ARG A  49
ALA A 218
GLY A 220
ALA A 112
GLY A 102
 None
None
GLC  A 253 (-3.1A)
None
None
 1.28A 4r29C-1n3pA:
undetectable		 4r29C-1n3pA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 10 ASP A 150
VAL A 185
VAL A 174
PHE A 129
ALA A  89
 None
 1.22A 4twlA-1n3pA:
undetectable		 4twlA-1n3pA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 10 ASP A 150
VAL A 185
VAL A 174
PHE A 129
ALA A  89
 None
 1.25A 4twlB-1n3pA:
undetectable		 4twlB-1n3pA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		3 / 3 VAL A 186
THR A 188
ARG A 194
 None
 0.63A 5b2sB-1n3pA:
undetectable		 5b2sB-1n3pA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		3 / 3 VAL A 186
THR A 188
ARG A 194
 None
 0.64A 5b2tB-1n3pA:
undetectable		 5b2tB-1n3pA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 THR A  46
ALA A  44
GLY A  87
ALA A  85
THR A 131
 None
None
None
GLC  A 253 ( 3.7A)
None
 1.07A 5lf7V-1n3pA:
undetectable
5lf7b-1n3pA:
undetectable		 5lf7V-1n3pA:
21.24
5lf7b-1n3pA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 THR A  46
ALA A  44
GLY A  87
ALA A  85
THR A 131
 None
None
None
GLC  A 253 ( 3.7A)
None
 1.06A 5lf7H-1n3pA:
undetectable
5lf7N-1n3pA:
undetectable		 5lf7H-1n3pA:
21.24
5lf7N-1n3pA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		3 / 3 HIS A  57
GLU A 209
TRP A 210
 None
 1.21A 5odiD-1n3pA:
undetectable		 5odiD-1n3pA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		3 / 3 HIS A  57
GLU A 209
TRP A 210
 None
 1.19A 5odqD-1n3pA:
undetectable		 5odqD-1n3pA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		3 / 3 HIS A  57
GLU A 209
TRP A 210
 None
 1.20A 5odrD-1n3pA:
undetectable		 5odrD-1n3pA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.24A 5wauC-1n3pA:
undetectable
5wauJ-1n3pA:
undetectable		 5wauC-1n3pA:
20.47
5wauJ-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.23A 5wauc-1n3pA:
undetectable
5wauj-1n3pA:
undetectable		 5wauc-1n3pA:
20.47
5wauj-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.25A 5xdqC-1n3pA:
undetectable
5xdqJ-1n3pA:
0.0		 5xdqC-1n3pA:
20.47
5xdqJ-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 5 PHE A  90
PHE A 215
LEU A 228
PHE A  11
 None
 1.24A 5xdqP-1n3pA:
undetectable
5xdqW-1n3pA:
0.0		 5xdqP-1n3pA:
20.47
5xdqW-1n3pA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		4 / 6 ASP A 150
GLN A 117
GLU A 128
THR A 131
 None
None
MN  A 271 (-2.8A)
None
 1.50A 6djzA-1n3pA:
0.0		 6djzA-1n3pA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1n3p LECTIN PAL
(Pterocarpus
angolensis) 		5 / 12 LEU A  18
ILE A  50
LEU A 110
GLY A  22
ALA A 218
 None
 1.31A 6qxsD-1n3pA:
0.0		 6qxsD-1n3pA:
21.97