SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		5 / 12 PHE A 184
ILE A 263
VAL A 134
ILE A 314
ILE A 159
 None
 1.18A 1r5lA-1n3yA:
undetectable		 1r5lA-1n3yA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		4 / 8 GLN A 202
ASP A 240
TYR A 208
SER A 142
 None
 0.88A 2xz5C-1n3yA:
0.0
2xz5D-1n3yA:
0.0		 2xz5C-1n3yA:
21.63
2xz5D-1n3yA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		5 / 10 ILE A 213
ALA A 257
SER A 290
ILE A 294
ILE A 285
 None
 1.23A 3qgtB-1n3yA:
undetectable		 3qgtB-1n3yA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		4 / 5 ASP A 138
SER A 175
GLY A 205
ASP A 240
 None
 1.31A 3w9tB-1n3yA:
undetectable		 3w9tB-1n3yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		4 / 5 ASP A 138
SER A 175
GLY A 205
ASP A 240
 None
 1.32A 3w9tC-1n3yA:
undetectable		 3w9tC-1n3yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		4 / 7 ILE A 159
VAL A 269
ILE A 306
PHE A 300
 None
 0.98A 5hieC-1n3yA:
undetectable		 5hieC-1n3yA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1n3y INTEGRIN ALPHA-X
(Homo
sapiens) 		4 / 8 GLY A 139
GLN A 173
SER A 142
PHE A 300
 None
 0.92A 6eqpA-1n3yA:
3.2		 6eqpA-1n3yA:
18.32