SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 8 MET A  75
LEU A 105
PRO A  42
GLY A 212
 None
None
None
TNR  A1401 ( 3.7A)
 1.02A 1hrkA-1n47A:
undetectable		 1hrkA-1n47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 8 MET A  75
LEU A 105
PRO A  42
GLY A 212
 None
None
None
TNR  A1401 ( 3.7A)
 0.96A 1hrkB-1n47A:
undetectable		 1hrkB-1n47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 12 THR A  69
ILE A  58
ILE A  19
ALA A  53
THR A   4
 None
 1.16A 1jtxA-1n47A:
undetectable		 1jtxA-1n47A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 6 LEU A 105
GLY A 103
ASN A 129
ILE A 145
 None
TNR  A1401 (-3.4A)
TNR  A1401 ( 3.1A)
None
 0.86A 1xf1B-1n47A:
undetectable		 1xf1B-1n47A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 8 MET A  75
LEU A 105
PRO A  42
GLY A 212
 None
None
None
TNR  A1401 ( 3.7A)
 0.99A 2po5A-1n47A:
undetectable		 2po5A-1n47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 8 MET A  75
LEU A 105
PRO A  42
GLY A 212
 None
None
None
TNR  A1401 ( 3.7A)
 0.98A 2po5B-1n47A:
undetectable		 2po5B-1n47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 8 ASP A 141
GLY A 139
ASP A 132
GLY A  86
LEU A  87
 None
None
MN  A 253 ( 2.5A)
None
None
 1.38A 3em6A-1n47A:
undetectable		 3em6A-1n47A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 10 PHE A  73
PHE A  71
PHE A 180
ILE A 138
PHE A 124
 None
 1.37A 3t3qB-1n47A:
undetectable		 3t3qB-1n47A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 10 PHE A  73
PHE A  71
PHE A 180
ILE A 138
PHE A 124
 None
 1.35A 3t3qD-1n47A:
undetectable		 3t3qD-1n47A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 7 PHE A   8
ASN A  17
ALA A  53
LEU A  20
 None
 0.78A 4ejgC-1n47A:
undetectable		 4ejgC-1n47A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 12 GLY A 103
GLY A 102
GLY A  86
ILE A 138
TYR A 135
 TNR  A1401 (-3.4A)
TNR  A1401 ( 3.9A)
None
None
None
 1.05A 4rtmA-1n47A:
undetectable		 4rtmA-1n47A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 12 VAL A 189
ALA A 176
PHE A  73
ILE A 163
PHE A 124
 None
 1.37A 5hgcA-1n47A:
0.0		 5hgcA-1n47A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 6 ILE A 165
ALA A 175
LEU A 174
ILE A 140
 None
 0.82A 5mvmB-1n47A:
undetectable
5mvmC-1n47A:
undetectable		 5mvmB-1n47A:
15.67
5mvmC-1n47A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		4 / 6 ASN A  27
ALA A  29
PRO A  13
VAL A  26
 None
 1.16A 5umd2-1n47A:
undetectable
5umdF-1n47A:
undetectable		 5umd2-1n47A:
16.96
5umdF-1n47A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 12 ALA A 121
LEU A 195
ILE A  58
VAL A 205
PHE A 228
 None
 1.28A 5vlmE-1n47A:
undetectable		 5vlmE-1n47A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 12 LEU A  87
TYR A 157
MET A 155
PHE A 153
GLU A 123
 None
None
None
None
MN  A 253 (-2.7A)
 1.42A 5w8aA-1n47A:
0.0		 5w8aA-1n47A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_B_LLLB302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 1n47 ISOLECTIN B4
(Vicia
villosa) 		5 / 10 ASP A  85
GLY A 102
ASP A 222
THR A 220
SER A 208
 TNR  A1401 (-2.9A)
TNR  A1401 ( 3.9A)
None
None
None
 1.47A 6mn1B-1n47A:
0.0		 6mn1B-1n47A:
15.25