SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n4o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.26A 1ghmA-1n4oA:
36.3		 1ghmA-1n4oA:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
LYS A 234
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.37A 1i2wA-1n4oA:
38.8		 1i2wA-1n4oA:
37.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.2A)
 0.37A 1i2wB-1n4oA:
38.7		 1i2wB-1n4oA:
37.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 ASP A 179
LEU A 165
LEU A 169
 None
 0.77A 1ikeA-1n4oA:
0.0		 1ikeA-1n4oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 ASP A 179
LEU A 165
LEU A 169
 None
 0.77A 1np1B-1n4oA:
0.0		 1np1B-1n4oA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		9 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
LYS A 234
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.44A 1ymxA-1n4oA:
40.5		 1ymxA-1n4oA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 5 CYH A  69
PRO A 167
THR A 235
SER A 237
 None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-2.7A)
 0.57A 1ymxA-1n4oA:
40.5		 1ymxA-1n4oA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		9 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
SER A 237
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.36A 1ymxB-1n4oA:
40.8		 1ymxB-1n4oA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 5 CYH A  69
PRO A 167
THR A 216
THR A 235
 None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
 0.21A 1ymxB-1n4oA:
40.8		 1ymxB-1n4oA:
47.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 6 THR A 262
ASP A 246
THR A 235
ASP A 218
 None
None
SO4  A1002 (-3.6A)
None
 1.23A 2okcB-1n4oA:
undetectable		 2okcB-1n4oA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 7 ARG A  65
GLU A  64
ALA A 185
ALA A 184
 None
 0.93A 2zgwA-1n4oA:
undetectable		 2zgwA-1n4oA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 LEU A 190
SER A  74
SER A 160
LEU A 279
LEU A 225
 None
 1.37A 2zlcA-1n4oA:
0.0		 2zlcA-1n4oA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
SER A 237
 SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.44A 3hlwA-1n4oA:
40.5		 3hlwA-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
 SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.40A 3hlwB-1n4oA:
40.7		 3hlwB-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
LYS A  73
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
SER A 237
 None
SO4  A1002 ( 4.9A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.35A 3huoA-1n4oA:
40.5		 3huoA-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 6 THR A  51
LEU A 195
GLY A 196
ALA A 257
PRO A 258
 None
 0.51A 3huoA-1n4oA:
40.5		 3huoA-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 CYH A  69
LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
 None
SO4  A1002 ( 4.9A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.34A 3huoB-1n4oA:
40.7		 3huoB-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 LYS A  73
ASN A 132
LYS A 234
GLY A 236
ARG A 244
 SO4  A1002 ( 4.9A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
None
 0.80A 3huoB-1n4oA:
40.7		 3huoB-1n4oA:
46.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 9 THR A 149
ALA A 150
LEU A 152
ALA A 154
SER A 155
 None
 1.42A 3kp6B-1n4oA:
0.0		 3kp6B-1n4oA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 ASP A 242
ALA A  41
GLY A  42
LEU A  36
ILE A  27
 None
 0.92A 3ku1G-1n4oA:
undetectable		 3ku1G-1n4oA:
21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.47A 3ny4A-1n4oA:
37.2		 3ny4A-1n4oA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 8 LEU A 195
ARG A 204
GLY A 256
PRO A 258
 None
 0.82A 3ny4A-1n4oA:
37.2		 3ny4A-1n4oA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 8 LEU A 195
ARG A 204
TRP A 251
PRO A 258
 None
 0.75A 3ny4A-1n4oA:
37.2		 3ny4A-1n4oA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
 SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.53A 3q07A-1n4oA:
40.4		 3q07A-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
SER A 237
 SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.37A 3q07B-1n4oA:
40.6		 3q07B-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		6 / 12 SER A  70
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.16A 3sh8A-1n4oA:
37.4		 3sh8A-1n4oA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
TYR A 272
 SO4  A1002 (-2.9A)
SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
None
 0.64A 3sh8B-1n4oA:
37.5		 3sh8B-1n4oA:
35.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 9 GLU A 166
LEU A 169
SER A 162
VAL A 148
LEU A  76
 None
 1.48A 3uncA-1n4oA:
undetectable		 3uncA-1n4oA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 9 GLU A 166
LEU A 169
SER A 162
VAL A 148
LEU A  76
 None
 1.48A 3uncB-1n4oA:
undetectable		 3uncB-1n4oA:
12.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		9 / 12 LYS A  73
HIS A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 ( 4.9A)
None
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.43A 4euzA-1n4oA:
38.6		 4euzA-1n4oA:
40.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 10 SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-3.1A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.53A 4fh2A-1n4oA:
35.9		 4fh2A-1n4oA:
38.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.20A 4n9kA-1n4oA:
39.2		 4n9kA-1n4oA:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
TYR A 272
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
None
 0.77A 4n9kB-1n4oA:
39.1		 4n9kB-1n4oA:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
SER A 237
 SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.61A 4pm5A-1n4oA:
40.4		 4pm5A-1n4oA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 SO4  A1002 ( 4.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.67A 4pm7A-1n4oA:
40.4		 4pm7A-1n4oA:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.62A 4pm9A-1n4oA:
40.5		 4pm9A-1n4oA:
48.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 ASP A 101
HIS A 112
VAL A  97
LEU A 122
ALA A 125
 None
 1.11A 4yhaA-1n4oA:
undetectable		 4yhaA-1n4oA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 10 ASP A 101
HIS A 112
VAL A  97
LEU A 122
ALA A 125
 None
 1.20A 4yhaB-1n4oA:
undetectable		 4yhaB-1n4oA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 TRP A 210
ARG A 120
LEU A 138
 None
 0.95A 5dbyA-1n4oA:
undetectable		 5dbyA-1n4oA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 ASN A 245
LEU A 190
PHE A  72
 None
 0.78A 5dsgA-1n4oA:
undetectable		 5dsgA-1n4oA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 ASP A 233
ASN A 245
PHE A  72
 None
 0.72A 5dsgB-1n4oA:
undetectable		 5dsgB-1n4oA:
21.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
TYR A 272
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
None
 0.79A 5ghyA-1n4oA:
39.1		 5ghyA-1n4oA:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
TYR A 272
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
None
 0.79A 5ghyB-1n4oA:
39.2		 5ghyB-1n4oA:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 11 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.25A 5ghzA-1n4oA:
39.0		 5ghzA-1n4oA:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 10 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.23A 5ghzB-1n4oA:
39.0		 5ghzB-1n4oA:
35.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 ASP A 242
ALA A 243
GLN A  62
GLY A  45
THR A  47
 None
 0.88A 5hfjC-1n4oA:
undetectable		 5hfjC-1n4oA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 12 GLY A  45
ALA A 243
ASN A 245
PHE A 172
LYS A 174
 None
 1.39A 5kc4E-1n4oA:
undetectable		 5kc4E-1n4oA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 8 HIS A 112
VAL A  97
LEU A 122
ALA A 125
 None
 0.85A 5tt3H-1n4oA:
undetectable		 5tt3H-1n4oA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		4 / 4 PHE A 151
LEU A  90
LEU A  81
VAL A 142
 None
 1.35A 5xxiA-1n4oA:
0.0		 5xxiA-1n4oA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		3 / 3 ASP A 242
PHE A 172
ARG A  43
 None
 1.11A 5yw0A-1n4oA:
0.0		 5yw0A-1n4oA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.40A 6b5yB-1n4oA:
37.5		 6b5yB-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.40A 6b5yD-1n4oA:
37.6		 6b5yD-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.26A 6b68B-1n4oA:
37.7		 6b68B-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		6 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.32A 6b68D-1n4oA:
37.6		 6b68D-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.29A 6b69A-1n4oA:
37.6
6b69B-1n4oA:
37.6		 6b69A-1n4oA:
17.72
6b69B-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.27A 6b69D-1n4oA:
37.5		 6b69D-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.30A 6b6aB-1n4oA:
37.4		 6b6aB-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		6 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.25A 6b6aD-1n4oA:
37.2		 6b6aD-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.39A 6b6cA-1n4oA:
37.6		 6b6cA-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.53A 6b6dA-1n4oA:
37.4		 6b6dA-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.29A 6b6eA-1n4oA:
37.6		 6b6eA-1n4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		8 / 12 CYH A  69
SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
SO4  A1002 (-2.9A)
SO4  A1002 (-3.1A)
None
None
SO4  A1002 (-3.6A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
 0.44A 6b6fA-1n4oA:
37.4		 6b6fA-1n4oA:
17.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		7 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
SER A 237
 SO4  A1002 (-3.1A)
None
None
SO4  A1002 ( 4.8A)
SO4  A1002 (-3.6A)
SO4  A1002 (-3.2A)
SO4  A1002 (-2.7A)
 0.37A 6c79A-1n4oA:
40.5		 6c79A-1n4oA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1n4o L2 BETA-LACTAMASE
(Stenotrophomonas
maltophilia) 		5 / 10 GLY A 226
TRP A 229
LEU A 221
GLY A 283
LEU A 152
 None
 1.44A 6hqbA-1n4oA:
undetectable
6hqbJ-1n4oA:
0.0		 6hqbA-1n4oA:
13.72
6hqbJ-1n4oA:
10.97