SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n4x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WFH_B_P2EB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)
1n4x IMMUNOGLOBULIN HEAVY
CHAIN VARIABLE
REGION

(Mus
musculus)
5 / 12 HIS H 335
VAL H 337
TRP H 350
TYR H 403
TRP H 410
None
1.13A 3wfhA-1n4xH:
21.1
3wfhB-1n4xH:
15.6
3wfhA-1n4xH:
49.17
3wfhB-1n4xH:
20.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WHX_B_XPGB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)
1n4x IMMUNOGLOBULIN HEAVY
CHAIN VARIABLE
REGION

(Mus
musculus)
5 / 12 HIS H 335
VAL H 337
TRP H 350
TYR H 403
TRP H 410
None
1.13A 3whxA-1n4xH:
21.2
3whxB-1n4xH:
15.6
3whxA-1n4xH:
49.17
3whxB-1n4xH:
20.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)
1n4x IMMUNOGLOBULIN HEAVY
CHAIN VARIABLE
REGION

(Mus
musculus)
4 / 5 VAL H 302
TYR H 327
ARG H 398
TYR H 409
None
0.16A 4m7kH-1n4xH:
22.0
4m7kH-1n4xH:
49.17