SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J78_B_VDYB500_1
(VITAMIN D BINDING
PROTEIN)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		5 / 10 GLU A 165
VAL A 168
PHE A 114
TYR A 207
LEU A 125
 None
 1.43A 1j78B-1n5dA:
1.9		 1j78B-1n5dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.92A 1jnoA-1n5dA:
undetectable		 1jnoA-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.91A 1jnoB-1n5dA:
undetectable		 1jnoB-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.93A 1ng8A-1n5dA:
undetectable		 1ng8A-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.93A 1ng8B-1n5dA:
undetectable		 1ng8B-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.94A 1nruA-1n5dA:
undetectable		 1nruA-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.93A 1nruB-1n5dA:
undetectable		 1nruB-1n5dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 7 THR A 192
VAL A 195
THR A 196
THR A 109
 None
 0.82A 3deuA-1n5dA:
undetectable		 3deuA-1n5dA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 ALA A  40
ARG A  41
LYS A  14
 None
NDP  A 300 (-3.5A)
NDP  A 300 (-3.8A)
 1.00A 3kp5B-1n5dA:
0.0		 3kp5B-1n5dA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 4 LEU A 170
GLY A 169
LEU A 167
GLU A 166
 None
 1.13A 3tgvB-1n5dA:
undetectable		 3tgvB-1n5dA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 5 SER A 139
ILE A  16
TYR A 193
GLY A 228
 NDP  A 300 (-3.5A)
NDP  A 300 (-3.6A)
NDP  A 300 (-4.8A)
None
 0.94A 3uboB-1n5dA:
5.9		 3uboB-1n5dA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 8 LEU A  72
ILE A  69
ASN A 119
GLY A 116
 None
 0.89A 3wxoA-1n5dA:
undetectable		 3wxoA-1n5dA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 7 ILE A 162
ARG A 209
VAL A 200
MET A 115
 None
 1.40A 4f4dA-1n5dA:
2.2		 4f4dA-1n5dA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		3 / 3 LEU A 256
PRO A 257
ARG A 212
 None
 0.65A 4klrB-1n5dA:
2.7		 4klrB-1n5dA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 6 ASN A 136
ALA A 224
PRO A 250
VAL A 135
 None
 1.13A 5umd2-1n5dA:
undetectable
5umdF-1n5dA:
undetectable		 5umd2-1n5dA:
12.46
5umdF-1n5dA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE
(Sus
scrofa) 		4 / 8 SER A 139
TYR A 193
TRP A 229
MET A 234
 NDP  A 300 (-3.5A)
NDP  A 300 (-4.8A)
None
NDP  A 300 (-3.5A)
 0.69A 5wqpA-1n5dA:
24.7		 5wqpA-1n5dA:
28.77