SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 5 PHE A 146
TYR A 147
LEU A  73
VAL A  78
 COA  A 601 (-3.7A)
None
None
COA  A 601 (-4.1A)
 1.23A 1dz6A-1n71A:
0.0		 1dz6A-1n71A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 ASP A 124
ASP A 165
LYS A 132
 None
 1.00A 1lqtB-1n71A:
undetectable		 1lqtB-1n71A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 ASP A 124
ASP A 165
LYS A 132
 None
 1.02A 1lquB-1n71A:
undetectable		 1lquB-1n71A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 ASP A  54
GLU A  79
ARG A  90
 None
 0.88A 1wopA-1n71A:
0.0		 1wopA-1n71A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		5 / 9 LEU A  76
ILE A  60
GLY A  61
GLU A  72
LEU A 109
 COA  A 601 (-4.2A)
None
None
None
None
 1.08A 3ai9X-1n71A:
undetectable		 3ai9X-1n71A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 ASN A 162
ASP A 168
ARG A  83
 None
None
COA  A 601 (-3.6A)
 0.88A 3k13A-1n71A:
undetectable		 3k13A-1n71A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 ASN A 162
ASP A 168
ARG A  83
 None
None
COA  A 601 (-3.6A)
 0.93A 3k13C-1n71A:
undetectable		 3k13C-1n71A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 5 LEU A  20
SER A  80
ARG A  83
LEU A  23
 None
None
COA  A 601 (-3.6A)
None
 1.35A 3onnA-1n71A:
undetectable		 3onnA-1n71A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 8 ARG A  22
LEU A  21
MET A  40
GLU A  36
 None
 1.08A 3zmdA-1n71A:
undetectable
3zmdB-1n71A:
undetectable		 3zmdA-1n71A:
23.44
3zmdB-1n71A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 7 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.71A 4iqqA-1n71A:
undetectable		 4iqqA-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 7 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.72A 4iqqB-1n71A:
undetectable		 4iqqB-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 7 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.78A 4iqqC-1n71A:
0.0		 4iqqC-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 8 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.63A 4iqqD-1n71A:
undetectable		 4iqqD-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 8 PHE A 146
TYR A 147
LEU A  73
VAL A  78
 COA  A 601 (-3.7A)
None
None
COA  A 601 (-4.1A)
 1.16A 4l4eA-1n71A:
0.0		 4l4eA-1n71A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 5 LEU A 139
GLY A 117
ILE A 136
LYS A 132
 None
 1.09A 4ma8C-1n71A:
0.0		 4ma8C-1n71A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 7 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.65A 5nooA-1n71A:
undetectable		 5nooA-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 7 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.62A 5nooB-1n71A:
undetectable		 5nooB-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		4 / 8 TYR A 144
ILE A 154
LEU A 109
GLY A 110
 None
 0.59A 5nooD-1n71A:
undetectable		 5nooD-1n71A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 1n71 AAC(6')-II
(Enterococcus
faecium) 		3 / 3 MET A  41
GLU A   5
ARG A   8
 None
 1.12A 5tjzA-1n71A:
undetectable		 5tjzA-1n71A:
18.29