SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 12 TYR A 400
LEU A 682
LEU A 683
LEU A 407
ILE A 381
 None
 1.40A 1fmlA-1n76A:
undetectable		 1fmlA-1n76A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 GLU A 413
HIS A 597
ASP A 645
 None
FE  A 694 ( 3.6A)
None
 0.87A 1i9gA-1n76A:
undetectable		 1i9gA-1n76A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 7 VAL A 158
LEU A 172
SER A 154
PHE A 153
 None
 0.89A 1j8uA-1n76A:
undetectable		 1j8uA-1n76A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.43A 1rqpA-1n76A:
2.6		 1rqpA-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.45A 1rqpB-1n76A:
0.4		 1rqpB-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 10 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.47A 1rqpC-1n76A:
0.4		 1rqpC-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 8 ASP A 570
GLY A 556
ASP A 560
THR A 638
 None
 0.98A 2aouA-1n76A:
undetectable		 2aouA-1n76A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ARG A 690
VAL A 399
GLY A 664
 None
 0.64A 2avvE-1n76A:
undetectable		 2avvE-1n76A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 8 TYR A 435
GLY A 527
GLY A 468
THR A 466
ALA A 467
 FE  A 694 ( 4.1A)
None
CO3  A 696 (-4.2A)
CO3  A 696 ( 4.7A)
CO3  A 696 (-3.4A)
 1.34A 2ej3C-1n76A:
undetectable		 2ej3C-1n76A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 7 SER A 114
SER A 156
VAL A 158
LEU A 331
 None
 1.04A 2hdnE-1n76A:
0.0
2hdnF-1n76A:
undetectable
2hdnH-1n76A:
undetectable		 2hdnE-1n76A:
5.60
2hdnF-1n76A:
19.19
2hdnH-1n76A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 7 SER A 156
VAL A 158
LEU A 331
SER A 114
 None
 1.01A 2hdnF-1n76A:
undetectable
2hdnG-1n76A:
0.0
2hdnH-1n76A:
undetectable		 2hdnF-1n76A:
19.19
2hdnG-1n76A:
5.60
2hdnH-1n76A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 5 LEU A 298
LEU A 299
LEU A 271
MET A  26
 None
 1.01A 2oaxF-1n76A:
0.0		 2oaxF-1n76A:
15.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 LEU A 653
TYR A 662
GLY A 664
 None
 0.47A 2ocuA-1n76A:
53.5		 2ocuA-1n76A:
41.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ASP A 555
ASN A 557
THR A 529
 None
 0.65A 2pymB-1n76A:
0.0		 2pymB-1n76A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ASP A 555
ASN A 557
THR A 529
 None
 0.77A 2q63B-1n76A:
undetectable		 2q63B-1n76A:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 GLN A 353
THR A 638
TRP A 562
 None
 0.83A 2rctA-1n76A:
0.0		 2rctA-1n76A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 8 SER A 252
TYR A  92
TYR A 192
HIS A 253
 None
FE  A 693 ( 4.2A)
CO3  A 695 ( 4.0A)
FE  A 693 ( 3.3A)
 1.30A 2v0gA-1n76A:
undetectable		 2v0gA-1n76A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.47A 2v7uC-1n76A:
0.4		 2v7uC-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.46A 2v7uA-1n76A:
0.1		 2v7uA-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1300_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 LEU A 298
ASP A 302
SER A 291
TRP A   8
THR A  10
 None
 1.48A 2v7uB-1n76A:
0.3		 2v7uB-1n76A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 12 THR A 647
LEU A 633
ALA A 651
VAL A 428
VAL A 369
 None
 0.99A 3czhB-1n76A:
undetectable		 3czhB-1n76A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 12 GLY A 474
ASN A 478
GLY A 397
ASN A 673
THR A 401
 None
 1.16A 3eeyF-1n76A:
undetectable		 3eeyF-1n76A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 TYR A 324
TYR A  92
GLY A  61
 None
FE  A 693 ( 4.2A)
None
 0.74A 3eteB-1n76A:
undetectable
3eteD-1n76A:
undetectable
3eteF-1n76A:
undetectable		 3eteB-1n76A:
21.70
3eteD-1n76A:
21.70
3eteF-1n76A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 TYR A 667
TYR A 435
GLY A 397
 None
FE  A 694 ( 4.1A)
None
 0.73A 3eteB-1n76A:
undetectable
3eteD-1n76A:
undetectable
3eteF-1n76A:
undetectable		 3eteB-1n76A:
21.70
3eteD-1n76A:
21.70
3eteF-1n76A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 PRO A 519
SER A 375
ASN A 515
 None
 0.93A 3lslG-1n76A:
7.4		 3lslG-1n76A:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 7 GLY A 434
PRO A 595
ASN A 596
TYR A 662
GLY A 664
 None
 0.43A 3tajA-1n76A:
52.9		 3tajA-1n76A:
41.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 LYS A 581
PRO A 582
LEU A 573
 None
 0.85A 3tpxE-1n76A:
0.0		 3tpxE-1n76A:
9.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 5 GLY A 434
PRO A 595
ASN A 596
TYR A 662
 None
 0.30A 3u8qA-1n76A:
52.9		 3u8qA-1n76A:
68.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 GLN A 329
PHE A 325
TYR A  65
 None
 0.94A 3ucjB-1n76A:
undetectable		 3ucjB-1n76A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 GLN A 329
PHE A 325
TYR A  65
 None
 0.96A 3ucjA-1n76A:
undetectable		 3ucjA-1n76A:
17.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 6 GLY A 434
PRO A 595
GLY A 664
TYR A 667
 None
 0.50A 4dxuA-1n76A:
52.9		 4dxuA-1n76A:
68.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 6 ASN A 640
ARG A 465
TYR A 435
TYR A 528
 None
CO3  A 696 (-4.1A)
FE  A 694 ( 4.1A)
CO3  A 696 ( 4.2A)
 1.40A 4f8yA-1n76A:
undetectable
4f8yB-1n76A:
undetectable		 4f8yA-1n76A:
14.24
4f8yB-1n76A:
14.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		6 / 9 GLU A 433
GLY A 434
PRO A 595
TYR A 662
GLY A 664
TYR A 667
 None
 0.58A 4fimA-1n76A:
53.0		 4fimA-1n76A:
68.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 6 GLY A 434
PRO A 595
ASN A 596
TYR A 662
GLY A 664
 None
 0.40A 4fjpA-1n76A:
53.0		 4fjpA-1n76A:
68.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 7 GLY A 434
PRO A 595
ASN A 596
TYR A 662
GLY A 664
 None
 0.48A 4forA-1n76A:
53.0		 4forA-1n76A:
68.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 PRO A 251
TYR A 319
GLY A 321
 None
 0.47A 4g2zA-1n76A:
52.9		 4g2zA-1n76A:
68.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 PRO A 595
TYR A 662
GLY A 664
 None
 0.38A 4g2zA-1n76A:
52.9		 4g2zA-1n76A:
68.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 7 HIS A 246
ALA A 248
TYR A 324
ALA A 327
 None
 0.39A 4g77A-1n76A:
53.1		 4g77A-1n76A:
41.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 7 ILE A 471
LEU A 475
HIS A 590
ALA A 592
TYR A 667
 None
 0.67A 4g77A-1n76A:
53.1		 4g77A-1n76A:
41.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 6 THR A 117
PRO A 159
PHE A  63
PHE A 190
 CO3  A 695 (-2.9A)
None
None
None
 1.29A 4kf9A-1n76A:
0.0		 4kf9A-1n76A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 12 GLY A 124
GLY A 118
ILE A 209
ALA A 195
ALA A  94
 CO3  A 695 (-4.0A)
None
None
None
None
 1.15A 4kicA-1n76A:
undetectable		 4kicA-1n76A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.27A 4mm5A-1n76A:
undetectable		 4mm5A-1n76A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.25A 4mmbA-1n76A:
undetectable		 4mmbA-1n76A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.27A 4mmeA-1n76A:
undetectable		 4mmeA-1n76A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.26A 4mmeB-1n76A:
undetectable		 4mmeB-1n76A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.20A 4mmfA-1n76A:
undetectable		 4mmfA-1n76A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 9 VAL A 542
ALA A 543
GLY A 455
SER A 492
GLY A 540
 None
 1.21A 4mmfB-1n76A:
undetectable		 4mmfB-1n76A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 4 GLY A 124
LEU A 320
PHE A 325
ILE A 328
 CO3  A 695 (-4.0A)
None
None
None
 0.97A 4xv2A-1n76A:
undetectable		 4xv2A-1n76A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 4 GLY A 124
VAL A 127
PHE A 325
ILE A 328
 CO3  A 695 (-4.0A)
None
None
None
 1.14A 4xv2B-1n76A:
0.0		 4xv2B-1n76A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ILE A  43
PRO A  42
ILE A  46
 None
 0.44A 5hw8F-1n76A:
undetectable		 5hw8F-1n76A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.47A 5i1nC-1n76A:
undetectable		 5i1nC-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.16A 5i1nB-1n76A:
undetectable		 5i1nB-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.32A 5i1oC-1n76A:
0.0		 5i1oC-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.20A 5i1oA-1n76A:
undetectable		 5i1oA-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.34A 5i1pA-1n76A:
0.1		 5i1pA-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 ALA A 327
ASN A 330
LEU A 331
 None
 0.29A 5i1pD-1n76A:
undetectable		 5i1pD-1n76A:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA607_0
(ALPHA-AMYLASE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		4 / 4 ARG A 442
SER A 444
ASP A 445
ASN A 538
 None
 1.26A 6ag0A-1n76A:
0.0		 6ag0A-1n76A:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 LEU A  69
ASN A 126
LEU A 320
 None
 0.77A 6exiD-1n76A:
undetectable		 6exiD-1n76A:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 LEU A 320
SER A 322
PHE A 325
 None
 0.52A 6fgcA-1n76A:
1.2		 6fgcA-1n76A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1n76 LACTOFERRIN
(Homo
sapiens) 		3 / 3 PHE A  20
ARG A  24
GLN A  23
 None
 0.93A 6g1pB-1n76A:
0.0		 6g1pB-1n76A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 1n76 LACTOFERRIN
(Homo
sapiens) 		5 / 12 THR A 131
VAL A 250
TRP A 125
PRO A 144
GLY A 323
 None
 1.44A 6gngB-1n76A:
undetectable		 6gngB-1n76A:
20.33