SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n7r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 11 LEU A 517
HIS A 483
LEU A 450
VAL A 513
ILE A 504
 None
 1.14A 1ee2A-1n7rA:
undetectable		 1ee2A-1n7rA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 11 LEU A 517
HIS A 483
LEU A 450
VAL A 513
ILE A 504
 None
 1.12A 1ee2B-1n7rA:
undetectable		 1ee2B-1n7rA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		6 / 7 ARG A 243
ASN A 290
TYR A 408
ARG A 462
ARG A 466
ASN A 580
 BDP  A1003 ( 2.3A)
BDP  A1001 ( 3.8A)
NAG  A1002 ( 2.6A)
BDP  A1001 ( 3.1A)
NAG  A1002 (-3.4A)
BDP  A1001 ( 2.4A)
 0.74A 1f9gA-1n7rA:
65.1		 1f9gA-1n7rA:
99.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 TYR A 404
ARG A 462
ARG A 466
ASN A 580
 None
BDP  A1001 ( 3.1A)
NAG  A1002 (-3.4A)
BDP  A1001 ( 2.4A)
 1.03A 1f9gA-1n7rA:
65.1		 1f9gA-1n7rA:
99.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 ALA A 830
VAL A 834
TRP A 835
 None
 0.78A 1nt5A-1n7rA:
undetectable		 1nt5A-1n7rA:
3.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 ALA A 830
VAL A 834
TRP A 835
 None
 0.78A 1nt5B-1n7rA:
undetectable		 1nt5B-1n7rA:
3.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 THR A 553
LEU A 544
THR A 860
VAL A 858
 None
 0.87A 1uyuB-1n7rA:
undetectable		 1uyuB-1n7rA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 TYR A 543
ARG A 540
GLY A 565
ALA A 554
 None
 0.70A 2a1hA-1n7rA:
undetectable
2a1hB-1n7rA:
undetectable		 2a1hA-1n7rA:
19.59
2a1hB-1n7rA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 ALA A 653
THR A 553
PHE A 671
 None
 0.65A 2c6nB-1n7rA:
0.3		 2c6nB-1n7rA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 6 TYR A 604
PRO A 618
ILE A 696
LEU A 797
 None
 1.27A 2wekB-1n7rA:
undetectable		 2wekB-1n7rA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 THR A 519
GLN A 418
ARG A 355
ILE A 184
 BDP  A1005 (-3.5A)
BDP  A1005 (-3.6A)
NAG  A1004 ( 3.7A)
None
 1.14A 2xytH-1n7rA:
0.0		 2xytH-1n7rA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 TYR A 520
GLN A 527
ILE A 523
ASP A 192
 None
 1.11A 2xytH-1n7rA:
0.0		 2xytH-1n7rA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 TYR A 520
GLN A 527
ILE A 523
ASP A 192
 None
 1.09A 2xytI-1n7rA:
0.0		 2xytI-1n7rA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 TYR A 281
VAL A 329
TYR A 294
ILE A 296
 None
 1.33A 2xz5B-1n7rA:
0.0
2xz5E-1n7rA:
0.0		 2xz5B-1n7rA:
15.12
2xz5E-1n7rA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 ILE A 296
TYR A 281
VAL A 329
TYR A 294
 None
 1.35A 2xz5D-1n7rA:
0.0
2xz5E-1n7rA:
undetectable		 2xz5D-1n7rA:
15.12
2xz5E-1n7rA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A 813
PHE A 679
GLY A 794
LEU A 797
PHE A 594
 None
 1.24A 2zzmA-1n7rA:
0.0		 2zzmA-1n7rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 507
ASN A 452
GLY A 471
HIS A 472
ILE A 464
 None
 1.40A 3a25A-1n7rA:
undetectable		 3a25A-1n7rA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 THR A 553
LEU A 544
THR A 860
VAL A 858
 None
 0.90A 3fwiA-1n7rA:
undetectable		 3fwiA-1n7rA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 5 LYS A 839
SER A 644
LEU A 824
SER A 826
 None
 1.24A 3ijxH-1n7rA:
undetectable		 3ijxH-1n7rA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 4 LYS A 839
SER A 644
LEU A 824
SER A 826
 None
 1.31A 3ik6H-1n7rA:
0.0		 3ik6H-1n7rA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 5 LYS A 839
SER A 644
LEU A 824
SER A 826
 None
 1.29A 3iluH-1n7rA:
undetectable		 3iluH-1n7rA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A 454
ASP A 508
ASP A 600
 None
 0.66A 3jb2A-1n7rA:
2.7		 3jb2A-1n7rA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 572
PHE A 640
TYR A 840
PRO A 875
 None
 1.37A 3jqaA-1n7rA:
undetectable		 3jqaA-1n7rA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 572
PHE A 640
TYR A 840
PRO A 875
 None
 1.25A 3jqaC-1n7rA:
undetectable		 3jqaC-1n7rA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 572
PHE A 640
TYR A 840
PRO A 875
 None
 1.30A 3jqaD-1n7rA:
undetectable		 3jqaD-1n7rA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 6 ILE A 296
ALA A 292
ALA A 236
THR A 239
 None
BDP  A1001 ( 4.2A)
NAG  A1002 ( 4.8A)
BDP  A1003 ( 4.9A)
 0.86A 3mdrB-1n7rA:
undetectable		 3mdrB-1n7rA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 10 GLY A 619
PHE A 594
VAL A 731
PHE A 746
TYR A 795
 None
 1.41A 3r6wA-1n7rA:
0.0
3r6wB-1n7rA:
0.0		 3r6wA-1n7rA:
14.87
3r6wB-1n7rA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 10 VAL A 731
PHE A 746
TYR A 795
GLY A 619
PHE A 594
 None
 1.33A 3r6wA-1n7rA:
0.0
3r6wB-1n7rA:
undetectable		 3r6wA-1n7rA:
14.87
3r6wB-1n7rA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 11 GLY A 481
VAL A 478
GLU A 477
SER A 417
ILE A 482
 None
None
BDP  A1003 ( 4.4A)
None
None
 1.22A 3uawA-1n7rA:
undetectable		 3uawA-1n7rA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A 457
GLU A 470
GLY A 471
 None
 0.70A 3w9tA-1n7rA:
undetectable		 3w9tA-1n7rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A 431
LYS A 432
ASP A 433
 None
 0.64A 4a7tA-1n7rA:
1.9		 4a7tA-1n7rA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 616
THR A 695
ILE A 752
 None
 0.91A 4e0fB-1n7rA:
undetectable		 4e0fB-1n7rA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A 381
LEU A 416
ILE A 413
ILE A 485
 None
 0.80A 4em2A-1n7rA:
0.0		 4em2A-1n7rA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 5 TYR A 615
LEU A 636
THR A 589
MET A 593
 None
 1.33A 4mbsB-1n7rA:
0.0		 4mbsB-1n7rA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 377
ILE A 442
LEU A 497
GLY A 481
ILE A 413
 None
 1.12A 4o1eA-1n7rA:
undetectable		 4o1eA-1n7rA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A 813
LYS A 560
VAL A 834
GLY A 833
LEU A 673
 None
 1.23A 4ot2A-1n7rA:
2.0		 4ot2A-1n7rA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 5 VAL A 324
GLU A 326
VAL A 356
LYS A 357
 None
 1.33A 4p6vB-1n7rA:
0.0
4p6vE-1n7rA:
0.0		 4p6vB-1n7rA:
19.78
4p6vE-1n7rA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 354
ILE A 377
ILE A 296
LEU A 412
ILE A 485
 None
 1.09A 4pd4C-1n7rA:
0.0		 4pd4C-1n7rA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 5 GLU A 577
TYR A 408
ARG A 466
ARG A 462
 None
NAG  A1002 ( 2.6A)
NAG  A1002 (-3.4A)
BDP  A1001 ( 3.1A)
 1.21A 4yshB-1n7rA:
0.0		 4yshB-1n7rA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 ILE A 696
ILE A 742
PHE A 746
LEU A 596
 None
 0.75A 5fukA-1n7rA:
0.0
5fukB-1n7rA:
0.0		 5fukA-1n7rA:
13.71
5fukB-1n7rA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 507
VAL A 505
ALA A 475
PRO A 539
GLY A 453
 None
 1.37A 5tzoC-1n7rA:
undetectable		 5tzoC-1n7rA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 4 GLU A 246
THR A 305
THR A 268
LEU A 225
 BDP  A1005 (-2.7A)
None
None
None
 1.50A 5v96D-1n7rA:
undetectable		 5v96D-1n7rA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 7 GLY A 619
TRP A 670
ASP A 591
TYR A 588
 None
 1.26A 5vlmG-1n7rA:
3.2		 5vlmG-1n7rA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		3 / 3 GLY A 633
ASN A 575
ARG A 627
 None
 0.76A 5w7bD-1n7rA:
undetectable		 5w7bD-1n7rA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1n7r HYALURONIDASE
(Streptococcus
pneumoniae) 		4 / 8 GLU A 577
SER A 445
HIS A 440
LEU A 383
 None
 0.94A 5y2tB-1n7rA:
0.6		 5y2tB-1n7rA:
undetectable