SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1n7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 ALA A 499
VAL A   6
TRP A 501
 None
 0.97A 1av2A-1n7uA:
undetectable
1av2B-1n7uA:
undetectable		 1av2A-1n7uA:
2.71
1av2B-1n7uA:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 LEU A  35
ALA A 524
GLY A  46
TYR A  44
GLN A  40
 None
None
None
None
ACT  A 562 ( 4.0A)
 1.12A 1brpA-1n7uA:
0.3		 1brpA-1n7uA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 PHE A  83
TYR A 145
PRO A  85
 None
 1.03A 1mcnA-1n7uA:
undetectable
1mcnB-1n7uA:
0.2
1mcnP-1n7uA:
undetectable		 1mcnA-1n7uA:
15.86
1mcnB-1n7uA:
15.86
1mcnP-1n7uA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 ALA A 499
VAL A   6
TRP A 501
 None
 0.92A 1w5uA-1n7uA:
undetectable
1w5uB-1n7uA:
undetectable		 1w5uA-1n7uA:
2.71
1w5uB-1n7uA:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 TRP A 501
ALA A 499
VAL A   6
 None
 0.99A 1w5uA-1n7uA:
undetectable
1w5uB-1n7uA:
undetectable		 1w5uA-1n7uA:
2.71
1w5uB-1n7uA:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 VAL A  56
LEU A 324
THR A 128
THR A 319
GLY A 373
 None
None
None
None
ACT  A 561 ( 4.2A)
 1.18A 2cbrA-1n7uA:
0.9		 2cbrA-1n7uA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 8 TYR A  89
GLU A 111
TYR A 135
HIS A 136
 None
 0.97A 2ha4A-1n7uA:
undetectable		 2ha4A-1n7uA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 7 TYR A  89
GLU A 111
TYR A 135
HIS A 136
 None
 1.00A 2ha4B-1n7uA:
undetectable		 2ha4B-1n7uA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 GLY A 468
TYR A  44
GLY A  47
ILE A 432
ALA A 477
 None
 1.04A 2plwA-1n7uA:
undetectable		 2plwA-1n7uA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 LEU A 392
ASN A  78
ARG A  70
 None
 0.96A 2qhfA-1n7uA:
undetectable		 2qhfA-1n7uA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 8 ILE A 407
LEU A 396
TYR A 354
GLY A 401
 None
 0.80A 2vdbA-1n7uA:
undetectable		 2vdbA-1n7uA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 GLY A  48
GLY A 478
GLY A 468
THR A 481
ILE A  38
 None
 1.22A 2wa2A-1n7uA:
undetectable		 2wa2A-1n7uA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 GLY A 478
GLY A 468
GLY A 423
VAL A 520
ILE A 491
 None
 0.96A 3embA-1n7uA:
undetectable		 3embA-1n7uA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 12 PHE A 312
ILE A 311
ILE A 188
VAL A  99
ARG A 151
 None
 1.15A 3fpjB-1n7uA:
undetectable		 3fpjB-1n7uA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 LYS A 404
ILE A  38
PHE A 523
 None
 0.96A 3j7zS-1n7uA:
0.0
3j7za-1n7uA:
undetectable		 3j7zS-1n7uA:
11.03
3j7za-1n7uA:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 7 ALA A 227
ILE A 311
ARG A 151
GLY A 230
 None
None
None
ACT  A 560 (-4.0A)
 0.95A 3v4tH-1n7uA:
undetectable		 3v4tH-1n7uA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 ASP A 132
ASN A 142
SER A  62
 None
 0.76A 4obwA-1n7uA:
undetectable		 4obwA-1n7uA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 8 TYR A  89
PHE A 114
GLY A 224
ILE A 192
 None
 0.88A 4qoiA-1n7uA:
undetectable
4qoiB-1n7uA:
undetectable		 4qoiA-1n7uA:
17.58
4qoiB-1n7uA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 4 TYR A  44
THR A 360
GLY A  48
LEU A  35
 None
 1.04A 4w5nA-1n7uA:
0.0		 4w5nA-1n7uA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 8 ASN A 321
PRO A 322
PHE A  59
SER A  61
 None
ACT  A 561 ( 4.6A)
None
None
 0.99A 5amiB-1n7uA:
0.0		 5amiB-1n7uA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 7 ILE A 491
ILE A 494
PHE A 523
LEU A 454
 None
 0.79A 5fukA-1n7uA:
undetectable
5fukB-1n7uA:
undetectable		 5fukA-1n7uA:
17.35
5fukB-1n7uA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		5 / 10 PHE A 369
ILE A 370
TRP A 410
GLY A 374
GLY A 373
 None
None
None
None
ACT  A 561 ( 4.2A)
 1.44A 5lbtA-1n7uA:
undetectable
5lbtB-1n7uA:
undetectable		 5lbtA-1n7uA:
17.41
5lbtB-1n7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 7 ILE A  20
TRP A  34
ASP A  26
SER A  28
 None
 0.94A 5nr3A-1n7uA:
undetectable		 5nr3A-1n7uA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		3 / 3 ILE A 283
VAL A 263
PRO A 276
 None
 0.69A 5uunA-1n7uA:
undetectable		 5uunA-1n7uA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 5 TYR A 363
VAL A 357
PHE A 531
GLY A 527
 None
 1.18A 6hd4A-1n7uA:
undetectable		 6hd4A-1n7uA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1n7u ADSORPTION PROTEIN
P2
(Salmonella
virus
PRD1) 		4 / 6 ILE A 432
ALA A 439
ARG A 435
ASP A 408
 None
 0.99A 6hu9m-1n7uA:
undetectable
6hu9q-1n7uA:
undetectable		 6hu9m-1n7uA:
22.10
6hu9q-1n7uA:
12.59