SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1na6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		3 / 3 ALA A  80
GLY A  39
SER A 106
 None
 0.58A 2ivuA-1na6A:
undetectable		 2ivuA-1na6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 5 PRO A 371
PRO A 214
ILE A 393
GLY A 390
 None
 1.06A 2jkjD-1na6A:
0.0		 2jkjD-1na6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 5 PRO A 371
PRO A 214
ILE A 393
GLY A 390
 None
 1.07A 2jkjF-1na6A:
0.0		 2jkjF-1na6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.84A 2vxaA-1na6A:
0.0
2vxaC-1na6A:
0.0
2vxaE-1na6A:
0.0		 2vxaA-1na6A:
12.00
2vxaC-1na6A:
12.00
2vxaE-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.84A 2vxaA-1na6A:
0.0
2vxaB-1na6A:
0.0
2vxaK-1na6A:
0.0		 2vxaA-1na6A:
12.00
2vxaB-1na6A:
12.00
2vxaK-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.84A 2vxaB-1na6A:
0.0
2vxaC-1na6A:
0.0
2vxaG-1na6A:
0.0		 2vxaB-1na6A:
12.00
2vxaC-1na6A:
12.00
2vxaG-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.83A 2vxaD-1na6A:
0.0
2vxaF-1na6A:
0.0
2vxaI-1na6A:
0.0		 2vxaD-1na6A:
12.00
2vxaF-1na6A:
12.00
2vxaI-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.83A 2vxaD-1na6A:
0.0
2vxaE-1na6A:
0.0
2vxaL-1na6A:
0.0		 2vxaD-1na6A:
12.00
2vxaE-1na6A:
12.00
2vxaL-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ARG A 192
HIS A 190
TYR A 202
TRP A 189
 None
 0.83A 2vxaF-1na6A:
0.0
2vxaG-1na6A:
0.0
2vxaI-1na6A:
0.0		 2vxaF-1na6A:
12.00
2vxaG-1na6A:
12.00
2vxaI-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ARG A 192
HIS A 190
TYR A 202
TRP A 189
 None
 0.83A 2vxaB-1na6A:
0.0
2vxaG-1na6A:
0.0
2vxaH-1na6A:
0.0		 2vxaB-1na6A:
12.00
2vxaG-1na6A:
12.00
2vxaH-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 TYR A 202
TRP A 189
ARG A 192
HIS A 190
 None
 0.84A 2vxaH-1na6A:
0.0
2vxaI-1na6A:
0.0
2vxaJ-1na6A:
0.0		 2vxaH-1na6A:
12.00
2vxaI-1na6A:
12.00
2vxaJ-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ARG A 192
HIS A 190
TYR A 202
TRP A 189
 None
 0.85A 2vxaD-1na6A:
0.0
2vxaJ-1na6A:
0.0
2vxaL-1na6A:
0.0		 2vxaD-1na6A:
12.00
2vxaJ-1na6A:
12.00
2vxaL-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ARG A 192
HIS A 190
TYR A 202
TRP A 189
 None
 0.86A 2vxaH-1na6A:
0.0
2vxaJ-1na6A:
0.0
2vxaK-1na6A:
0.0		 2vxaH-1na6A:
12.00
2vxaJ-1na6A:
12.00
2vxaK-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ARG A 192
HIS A 190
TYR A 202
TRP A 189
 None
 0.84A 2vxaA-1na6A:
0.0
2vxaK-1na6A:
0.0
2vxaL-1na6A:
0.0		 2vxaA-1na6A:
12.00
2vxaK-1na6A:
12.00
2vxaL-1na6A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 ALA A  82
LEU A  66
ASP A 130
SER A  53
 None
 0.89A 3qj7A-1na6A:
undetectable
3qj7D-1na6A:
undetectable		 3qj7A-1na6A:
22.76
3qj7D-1na6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 8 SER A 269
GLU A 154
GLY A 158
LYS A  23
 None
 0.93A 4fgzA-1na6A:
undetectable
4fgzB-1na6A:
undetectable		 4fgzA-1na6A:
21.18
4fgzB-1na6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1na6 RESTRICTION
ENDONUCLEASE ECORII
(Escherichia
coli) 		4 / 5 TYR A 202
PHE A 193
LEU A 231
PRO A 194
 None
 1.38A 5csyB-1na6A:
2.6		 5csyB-1na6A:
22.49