SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1naa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.96A 1c6zB-1naaA:
undetectable		 1c6zB-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		3 / 3 GLN A 515
HIS A 727
PRO A 729
 None
 0.96A 1d8cA-1naaA:
undetectable		 1d8cA-1naaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 225
ALA A 741
GLY A 723
ALA A 740
ILE A 725
 6FA  A 801 (-3.3A)
None
None
None
None
 1.00A 1gtnL-1naaA:
undetectable
1gtnV-1naaA:
undetectable		 1gtnL-1naaA:
7.39
1gtnV-1naaA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
GLY A 228
GLY A 227
GLY A 470
ASN A 430
 6FA  A 801 (-3.0A)
None
6FA  A 801 (-4.1A)
6FA  A 801 ( 4.0A)
None
 0.87A 1n2xB-1naaA:
undetectable		 1n2xB-1naaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 243
VAL A 428
ILE A 474
SER A 478
LEU A 717
 None
6FA  A 801 (-4.0A)
None
None
None
 1.18A 1s19A-1naaA:
0.0		 1s19A-1naaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 11 GLY A 227
SER A 465
ALA A 231
ALA A 232
LEU A 244
 6FA  A 801 (-4.1A)
None
None
None
None
 1.12A 1ukbA-1naaA:
undetectable		 1ukbA-1naaA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 723
ALA A 740
ILE A 725
GLY A 225
ALA A 741
 None
None
None
6FA  A 801 (-3.3A)
None
 1.02A 1utdO-1naaA:
undetectable
1utdP-1naaA:
undetectable		 1utdO-1naaA:
7.39
1utdP-1naaA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 11 GLY A 723
ALA A 740
ILE A 725
GLY A 225
ALA A 741
 None
None
None
6FA  A 801 (-3.3A)
None
 1.02A 1utdP-1naaA:
undetectable
1utdQ-1naaA:
undetectable		 1utdP-1naaA:
7.39
1utdQ-1naaA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		3 / 3 SER A 478
VAL A 462
LEU A 717
 None
 0.73A 1yajG-1naaA:
1.0		 1yajG-1naaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.08A 2avsB-1naaA:
undetectable		 2avsB-1naaA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.03A 2f80A-1naaA:
undetectable		 2f80A-1naaA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.98A 2f80B-1naaA:
undetectable		 2f80B-1naaA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.99A 2f8gA-1naaA:
undetectable		 2f8gA-1naaA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 5 GLY A 479
TRP A 505
ARG A 433
LEU A 499
 None
 1.47A 2j2pD-1naaA:
0.0
2j2pF-1naaA:
0.0		 2j2pD-1naaA:
17.48
2j2pF-1naaA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 5 GLY A 310
HIS A 350
ASP A 382
ASP A 397
 6FA  A 801 (-3.4A)
None
None
None
 1.10A 2oxtB-1naaA:
2.3		 2oxtB-1naaA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.96A 2q64A-1naaA:
undetectable		 2q64A-1naaA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.02A 2qhcB-1naaA:
undetectable		 2qhcB-1naaA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 8 PHE A 282
PHE A 272
GLY A 299
ILE A 294
 ABL  A 901 (-4.1A)
None
None
None
 0.98A 2qwxA-1naaA:
2.5
2qwxB-1naaA:
3.0		 2qwxA-1naaA:
17.77
2qwxB-1naaA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		3 / 3 PRO A 275
GLY A 401
TYR A 550
 None
 0.73A 2vouA-1naaA:
10.6		 2vouA-1naaA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		3 / 3 PRO A 275
GLY A 401
TYR A 550
 None
 0.73A 2vouC-1naaA:
10.1		 2vouC-1naaA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 227
GLY A 225
ALA A 232
ASP A 721
VAL A 720
 6FA  A 801 (-4.1A)
6FA  A 801 (-3.3A)
None
6FA  A 801 (-4.3A)
None
 1.18A 2yvlD-1naaA:
2.5		 2yvlD-1naaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.01A 2z54A-1naaA:
undetectable		 2z54A-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.99A 3d1zB-1naaA:
undetectable		 3d1zB-1naaA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.07A 3d20A-1naaA:
undetectable		 3d20A-1naaA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 8 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.03A 3ekpA-1naaA:
undetectable		 3ekpA-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 8 LEU A 475
GLY A 467
ALA A 466
ILE A 221
ILE A 474
 None
6FA  A 801 (-3.3A)
6FA  A 801 (-3.4A)
None
None
 1.14A 3ekpA-1naaA:
undetectable		 3ekpA-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 8 LEU A 475
GLY A 467
ALA A 466
ILE A 463
ILE A 474
 None
6FA  A 801 (-3.3A)
6FA  A 801 (-3.4A)
None
None
 1.09A 3ekpA-1naaA:
undetectable		 3ekpA-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 11 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.00A 3ektD-1naaA:
undetectable		 3ektD-1naaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 10 ILE A 724
ILE A 719
GLY A 470
PHE A 469
LEU A 737
 None
None
6FA  A 801 ( 4.0A)
None
6FA  A 801 (-4.8A)
 1.21A 3elzB-1naaA:
undetectable		 3elzB-1naaA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 222
ALA A 231
ALA A 232
ALA A 745
VAL A 441
 6FA  A 801 (-4.8A)
None
None
None
None
 0.77A 3fc6C-1naaA:
undetectable		 3fc6C-1naaA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		6 / 12 LEU A 475
GLY A 467
ALA A 466
VAL A 428
ILE A 463
ILE A 474
 None
6FA  A 801 (-3.3A)
6FA  A 801 (-3.4A)
6FA  A 801 (-4.0A)
None
None
 1.11A 3jw2B-1naaA:
undetectable		 3jw2B-1naaA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 8 GLY A 481
PHE A 476
ILE A 719
PHE A 469
 None
 0.91A 3ko0O-1naaA:
0.4
3ko0Q-1naaA:
undetectable		 3ko0O-1naaA:
9.94
3ko0Q-1naaA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.99A 3lzsB-1naaA:
undetectable		 3lzsB-1naaA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.00A 3mwsA-1naaA:
undetectable		 3mwsA-1naaA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.02A 3ndwA-1naaA:
undetectable		 3ndwA-1naaA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		6 / 11 LEU A 475
GLY A 467
ALA A 466
VAL A 428
ILE A 463
ILE A 474
 None
6FA  A 801 (-3.3A)
6FA  A 801 (-3.4A)
6FA  A 801 (-4.0A)
None
None
 1.15A 3nu3B-1naaA:
undetectable		 3nu3B-1naaA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.13A 3nu5B-1naaA:
undetectable		 3nu5B-1naaA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 10 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.02A 3nu6B-1naaA:
undetectable		 3nu6B-1naaA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 10 LEU A 475
GLY A 467
ALA A 466
ILE A 463
ILE A 474
 None
6FA  A 801 (-3.3A)
6FA  A 801 (-3.4A)
None
None
 0.96A 3nu6B-1naaA:
undetectable		 3nu6B-1naaA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.01A 3oxxA-1naaA:
undetectable		 3oxxA-1naaA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.02A 3pwmA-1naaA:
undetectable		 3pwmA-1naaA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.96A 3tkwA-1naaA:
undetectable		 3tkwA-1naaA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 SER A 654
VAL A 653
ILE A 606
PHE A 524
HIS A 526
 None
 1.25A 4c49C-1naaA:
undetectable		 4c49C-1naaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 SER A 654
VAL A 653
ILE A 606
PHE A 524
HIS A 526
 None
 1.31A 4c49D-1naaA:
0.0		 4c49D-1naaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 5 GLY A 304
GLY A 305
ASN A 309
GLU A 246
 6FA  A 801 (-3.0A)
6FA  A 801 (-3.5A)
6FA  A 801 (-3.9A)
6FA  A 801 (-2.8A)
 1.23A 4fglC-1naaA:
3.1		 4fglC-1naaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 341
TYR A 337
ALA A 745
ASP A 721
GLY A 228
 None
None
None
6FA  A 801 (-4.3A)
None
 1.26A 4j7xA-1naaA:
undetectable		 4j7xA-1naaA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.01A 4njvA-1naaA:
undetectable		 4njvA-1naaA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 9 ALA A 745
ALA A 741
LEU A 341
SER A 236
LEU A 235
 None
 1.34A 4or0A-1naaA:
undetectable		 4or0A-1naaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 583
VAL A 608
ILE A 606
LEU A 370
ILE A 659
 None
 1.07A 4pd4C-1naaA:
undetectable		 4pd4C-1naaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 8 PHE A 282
PHE A 272
GLY A 299
ILE A 294
 ABL  A 901 (-4.1A)
None
None
None
 0.88A 4qoiA-1naaA:
3.3
4qoiB-1naaA:
3.3		 4qoiA-1naaA:
17.77
4qoiB-1naaA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A 229
ALA A 232
GLY A 305
GLY A 223
GLY A 405
 None
None
6FA  A 801 (-3.5A)
6FA  A 801 (-3.0A)
None
 0.95A 5i73A-1naaA:
undetectable		 5i73A-1naaA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 5 SER A 562
ASN A 517
GLN A 582
ASP A 516
 ABL  A 901 ( 4.2A)
None
None
None
 1.25A 5kpcA-1naaA:
2.0		 5kpcA-1naaA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 1.04A 5t2zA-1naaA:
undetectable		 5t2zA-1naaA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 745
VAL A 242
TYR A 219
 None
 0.67A 5zmqH-1naaA:
undetectable		 5zmqH-1naaA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.92A 6dgxA-1naaA:
undetectable		 6dgxA-1naaA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.93A 6dh3A-1naaA:
undetectable		 6dh3A-1naaA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 223
ALA A 224
VAL A 407
GLY A 305
ILE A 229
 6FA  A 801 (-3.0A)
6FA  A 801 ( 4.9A)
None
6FA  A 801 (-3.5A)
None
 0.93A 6dh6A-1naaA:
undetectable		 6dh6A-1naaA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1naa CELLOBIOSE
DEHYDROGENASE
(Phanerochaete
chrysosporium) 		4 / 6 VAL A 644
ASN A 517
PRO A 518
ILE A 614
 None
 1.19A 6h7uA-1naaA:
undetectable		 6h7uA-1naaA:
22.65