SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1naf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1naf ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ARG A 255
GLU A 220
ASN A 224
 None
 0.83A 4imaD-1nafA:
undetectable		 4imaD-1nafA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1naf ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ARG A 255
GLU A 220
ASN A 224
 None
 0.82A 4ip7D-1nafA:
undetectable		 4ip7D-1nafA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1naf ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ARG A 258
PHE A 264
LEU A 287
 None
 0.77A 5veuA-1nafA:
undetectable		 5veuA-1nafA:
17.05