SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nar'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 THR A 227
PHE A 260
PHE A 242
GLY A 224
 None
 1.01A 1icuA-1narA:
0.0
1icuB-1narA:
0.0		 1icuA-1narA:
22.34
1icuB-1narA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 PHE A 242
GLY A 224
THR A 227
PHE A 260
 None
 0.98A 1icuA-1narA:
0.0
1icuB-1narA:
0.0		 1icuA-1narA:
22.34
1icuB-1narA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 THR A 227
PHE A 260
PHE A 242
GLY A 224
 None
 0.94A 1icuC-1narA:
0.0
1icuD-1narA:
0.0		 1icuC-1narA:
22.34
1icuD-1narA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 5 PHE A 242
GLY A 224
THR A 227
PHE A 260
 None
 1.02A 1icuC-1narA:
0.0
1icuD-1narA:
0.0		 1icuC-1narA:
22.34
1icuD-1narA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 5 PHE A 242
GLY A 224
THR A 227
PHE A 260
 None
 1.05A 1icvA-1narA:
0.0
1icvB-1narA:
0.0		 1icvA-1narA:
22.34
1icvB-1narA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 THR A 227
PHE A 260
PHE A 242
GLY A 224
 None
 1.00A 1kqbA-1narA:
0.0
1kqbB-1narA:
undetectable		 1kqbA-1narA:
21.53
1kqbB-1narA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 THR A 227
PHE A 260
PHE A 242
GLY A 224
 None
 0.94A 1kqbC-1narA:
0.0
1kqbD-1narA:
0.0		 1kqbC-1narA:
21.53
1kqbD-1narA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 PHE A 242
GLY A 224
THR A 227
PHE A 260
 None
 1.00A 1kqbC-1narA:
0.0
1kqbD-1narA:
0.0		 1kqbC-1narA:
21.53
1kqbD-1narA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1nar NARBONIN
(Vicia
narbonensis) 		5 / 12 TYR A   8
GLY A  85
GLY A  86
ASP A  94
ASN A 170
 None
 1.18A 1qzzA-1narA:
undetectable		 1qzzA-1narA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 7 ALA A 165
TYR A 174
ASP A 128
TYR A   8
 None
 1.27A 2pncA-1narA:
undetectable		 2pncA-1narA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 8 PHE A 225
ILE A 237
GLY A 244
GLY A 245
 None
 0.79A 2qx4A-1narA:
undetectable
2qx4B-1narA:
undetectable		 2qx4A-1narA:
20.07
2qx4B-1narA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 PHE A 225
ILE A 237
GLY A 244
GLY A 245
 None
 0.81A 2qx6A-1narA:
2.1
2qx6B-1narA:
2.1		 2qx6A-1narA:
20.07
2qx6B-1narA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 7 ARG A  87
LYS A  12
SER A 226
ASP A 265
 None
 1.38A 2rk8B-1narA:
undetectable		 2rk8B-1narA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1nar NARBONIN
(Vicia
narbonensis) 		5 / 12 LEU A 151
LEU A 157
ILE A 124
SER A 117
ALA A 105
 None
 1.22A 3lbdA-1narA:
0.0		 3lbdA-1narA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 1nar NARBONIN
(Vicia
narbonensis) 		3 / 3 GLN A 195
PHE A 192
TYR A 190
 None
 0.98A 3ucjB-1narA:
undetectable		 3ucjB-1narA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1nar NARBONIN
(Vicia
narbonensis) 		3 / 3 PHE A 205
ASP A 203
ARG A 248
 None
 0.89A 4eahF-1narA:
1.0		 4eahF-1narA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1nar NARBONIN
(Vicia
narbonensis) 		3 / 3 PHE A 205
ASP A 203
ARG A 248
 None
 0.89A 4eahG-1narA:
1.2		 4eahG-1narA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 TYR A  44
THR A  51
PRO A  95
PHE A  54
 None
 1.09A 4kf9A-1narA:
0.0		 4kf9A-1narA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 7 TYR A  35
VAL A  68
ILE A 124
ILE A  82
 None
 0.74A 4lv9A-1narA:
2.3		 4lv9A-1narA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 7 TYR A  35
VAL A  68
ILE A 124
ILE A  82
 None
 0.74A 4lv9B-1narA:
3.2		 4lv9B-1narA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 1nar NARBONIN
(Vicia
narbonensis) 		3 / 3 GLU A 107
LYS A 106
ASN A 104
 None
 1.08A 4y1dA-1narA:
0.0
4y1dD-1narA:
undetectable		 4y1dA-1narA:
19.59
4y1dD-1narA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 8 GLU A 213
PRO A 223
GLY A 257
PRO A 256
 None
 1.14A 5kgpA-1narA:
0.9		 5kgpA-1narA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 8 GLU A 213
PRO A 223
GLY A 257
PRO A 256
 None
 1.11A 5kgpB-1narA:
undetectable		 5kgpB-1narA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 6 GLY A  85
GLU A  42
PHE A  39
ILE A  82
 None
 0.82A 5kmfA-1narA:
0.0
5kmfC-1narA:
undetectable		 5kmfA-1narA:
20.18
5kmfC-1narA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 4 VAL A 221
VAL A 188
TYR A 178
GLN A 175
 None
 1.48A 5qggA-1narA:
0.0		 5qggA-1narA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1nar NARBONIN
(Vicia
narbonensis) 		5 / 12 LEU A  71
PHE A  33
VAL A  80
PHE A 277
THR A 227
 None
 1.22A 5xipA-1narA:
undetectable		 5xipA-1narA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1nar NARBONIN
(Vicia
narbonensis) 		4 / 7 ASP A 156
ASP A 154
GLN A 114
LYS A 106
 None
 1.37A 6g31A-1narA:
undetectable		 6g31A-1narA:
13.17