SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 12 PRO A  11
GLY A 107
ASN A 113
SER A  68
GLY A 111
None
1.12A 1ffyA-1nb2A:
undetectable
1ffyA-1nb2A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 5 LEU A  89
GLY A 117
HIS A 116
ILE A 115
None
0.89A 1xf1A-1nb2A:
undetectable
1xf1A-1nb2A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 6 LEU A  89
GLY A 117
HIS A 116
ILE A 115
None
0.89A 1xf1B-1nb2A:
undetectable
1xf1B-1nb2A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 6 HIS A 116
GLU A 127
ASP A 119
SER A 123
None
1.39A 4apjA-1nb2A:
undetectable
4apjP-1nb2A:
undetectable
4apjA-1nb2A:
15.11
4apjP-1nb2A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 7 GLY A 117
ALA A 124
SER A 118
GLU A   3
None
0.87A 4hyfA-1nb2A:
undetectable
4hyfA-1nb2A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 8 GLY A 117
ALA A 124
SER A 118
GLU A   3
None
0.87A 4hyfB-1nb2A:
undetectable
4hyfB-1nb2A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
4 / 8 GLY A 117
ALA A 124
SER A 118
GLU A   3
None
0.87A 4hyfC-1nb2A:
undetectable
4hyfC-1nb2A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvlK-1nb2A:
undetectable
4qvlL-1nb2A:
undetectable
4qvlK-1nb2A:
22.48
4qvlL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvlY-1nb2A:
undetectable
4qvlZ-1nb2A:
undetectable
4qvlY-1nb2A:
22.48
4qvlZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvmK-1nb2A:
undetectable
4qvmL-1nb2A:
undetectable
4qvmK-1nb2A:
22.48
4qvmL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvmY-1nb2A:
undetectable
4qvmZ-1nb2A:
undetectable
4qvmY-1nb2A:
22.48
4qvmZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.04A 4qvnK-1nb2A:
undetectable
4qvnL-1nb2A:
undetectable
4qvnK-1nb2A:
22.48
4qvnL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.04A 4qvnY-1nb2A:
undetectable
4qvnZ-1nb2A:
undetectable
4qvnY-1nb2A:
22.48
4qvnZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.06A 4qvpK-1nb2A:
undetectable
4qvpL-1nb2A:
undetectable
4qvpK-1nb2A:
22.48
4qvpL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.06A 4qvpY-1nb2A:
undetectable
4qvpZ-1nb2A:
undetectable
4qvpY-1nb2A:
22.48
4qvpZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.04A 4qvqK-1nb2A:
undetectable
4qvqL-1nb2A:
undetectable
4qvqK-1nb2A:
22.48
4qvqL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.04A 4qvqY-1nb2A:
undetectable
4qvqZ-1nb2A:
undetectable
4qvqY-1nb2A:
22.48
4qvqZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvwK-1nb2A:
undetectable
4qvwL-1nb2A:
undetectable
4qvwK-1nb2A:
20.93
4qvwL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 4qvwY-1nb2A:
undetectable
4qvwZ-1nb2A:
undetectable
4qvwY-1nb2A:
20.93
4qvwZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.05A 4qw1Y-1nb2A:
undetectable
4qw1Z-1nb2A:
undetectable
4qw1Y-1nb2A:
20.93
4qw1Z-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.02A 4qw3K-1nb2A:
undetectable
4qw3L-1nb2A:
undetectable
4qw3K-1nb2A:
22.48
4qw3L-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 10 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.02A 4qw3Y-1nb2A:
undetectable
4qw3Z-1nb2A:
undetectable
4qw3Y-1nb2A:
22.48
4qw3Z-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 THR A  84
ALA A  82
THR A   5
ALA A 124
GLY A  78
None
1.13A 4qwuK-1nb2A:
undetectable
4qwuL-1nb2A:
undetectable
4qwuK-1nb2A:
22.48
4qwuL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 THR A  84
ALA A  82
THR A   5
ALA A 124
GLY A  78
None
1.11A 4qwuY-1nb2A:
undetectable
4qwuZ-1nb2A:
undetectable
4qwuY-1nb2A:
22.48
4qwuZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 5bxnK-1nb2A:
undetectable
5bxnL-1nb2A:
undetectable
5bxnK-1nb2A:
22.48
5bxnL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 11 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.02A 5bxnY-1nb2A:
undetectable
5bxnZ-1nb2A:
undetectable
5bxnY-1nb2A:
22.48
5bxnZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 5d0xK-1nb2A:
undetectable
5d0xL-1nb2A:
undetectable
5d0xK-1nb2A:
22.69
5d0xL-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.03A 5d0xY-1nb2A:
undetectable
5d0xZ-1nb2A:
undetectable
5d0xY-1nb2A:
22.69
5d0xZ-1nb2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.06A 5l5zK-1nb2A:
undetectable
5l5zL-1nb2A:
undetectable
5l5zK-1nb2A:
21.92
5l5zL-1nb2A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  83
GLY A  90
ASP A 119
None
1.09A 5l5zK-1nb2A:
undetectable
5l5zL-1nb2A:
undetectable
5l5zK-1nb2A:
21.92
5l5zL-1nb2A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  82
GLY A  90
ASP A 119
None
1.05A 5l5zY-1nb2A:
undetectable
5l5zZ-1nb2A:
undetectable
5l5zY-1nb2A:
21.92
5l5zZ-1nb2A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1nb2 NUCLEOSIDE
DIPHOSPHATE KINASE

(Virgibacillus
halodenitrifican
s)
5 / 9 ALA A  85
THR A  84
ALA A  83
GLY A  90
ASP A 119
None
1.08A 5l5zY-1nb2A:
undetectable
5l5zZ-1nb2A:
undetectable
5l5zY-1nb2A:
21.92
5l5zZ-1nb2A:
21.56