SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		3 / 3 GLU A  35
LYS A 125
VAL A  38
 None
 0.96A 1l2iA-1nbqA:
undetectable		 1l2iA-1nbqA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 6 LYS A  47
VAL A  60
VAL A 122
ILE A  94
 None
 1.10A 3pyyA-1nbqA:
undetectable		 3pyyA-1nbqA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 7 PHE A  55
TYR A  52
VAL A  31
GLU A 113
 None
 1.07A 4a97E-1nbqA:
0.0		 4a97E-1nbqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 8 PHE A  55
TYR A  52
VAL A  31
GLU A 113
 None
 1.09A 4a97G-1nbqA:
0.0		 4a97G-1nbqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 7 PHE A  55
TYR A  52
VAL A  31
GLU A 113
 None
 1.14A 4a97H-1nbqA:
undetectable		 4a97H-1nbqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 8 PHE A  55
TYR A  52
VAL A  31
GLU A 113
 None
 1.09A 4a97I-1nbqA:
undetectable		 4a97I-1nbqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 8 PRO A 131
TYR A 218
SER A  98
ASN A  43
 None
 1.13A 5l1fA-1nbqA:
undetectable
5l1fB-1nbqA:
undetectable		 5l1fA-1nbqA:
15.03
5l1fB-1nbqA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1nbq JUNCTIONAL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 6 GLU A 121
TYR A 119
GLY A 116
GLY A 115
 None
 0.82A 5x7pB-1nbqA:
undetectable		 5x7pB-1nbqA:
10.83