SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nbw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 9 ILE A 134
VAL A 197
GLY A 196
ALA A 199
LEU A 249
 None
 1.06A 1e7bA-1nbwA:
0.3		 1e7bA-1nbwA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 THR A 404
PRO A 405
GLY A 406
CYH A 407
 None
 0.86A 1h4oB-1nbwA:
undetectable		 1h4oB-1nbwA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 ASP B  95
GLY B 101
ASP A 185
ASP A 169
 None
 0.80A 1m4iA-1nbwB:
undetectable		 1m4iA-1nbwB:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 THR A 404
PRO A 405
GLY A 406
CYH A 407
 None
 0.89A 1oc3A-1nbwA:
undetectable		 1oc3A-1nbwA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 341
THR A  86
ALA A 263
GLY A 360
LEU A 447
 None
 1.09A 1rjdB-1nbwA:
undetectable		 1rjdB-1nbwA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 341
THR A  86
ALA A 263
GLY A 360
LEU A 447
 None
 1.09A 1rjdC-1nbwA:
undetectable		 1rjdC-1nbwA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 286
ALA A 289
ILE A 331
ARG A 315
LEU A 311
 None
 1.01A 1rx2A-1nbwA:
undetectable		 1rx2A-1nbwA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 286
ALA A 289
ILE A 331
ARG A 315
LEU A 311
 None
 1.00A 1rx3A-1nbwA:
undetectable		 1rx3A-1nbwA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 286
ALA A 289
ILE A 331
ARG A 315
LEU A 311
 None
 0.98A 1rx8A-1nbwA:
undetectable		 1rx8A-1nbwA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 ALA A  17
SER A  31
ASN A 594
ILE A 586
 None
 0.88A 1yc2A-1nbwA:
3.7		 1yc2A-1nbwA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 ALA A  17
SER A  31
ASN A 594
ILE A 586
 None
 0.89A 1yc5A-1nbwA:
2.6		 1yc5A-1nbwA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 LEU B 107
LEU B  74
ALA B  73
ILE B  64
ALA B  55
 None
 1.20A 2bxpA-1nbwB:
undetectable		 2bxpA-1nbwB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 4 VAL A 201
LEU A 121
ILE A 158
LEU A 154
 None
 0.91A 2byoA-1nbwA:
0.0		 2byoA-1nbwA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.19A 2f162-1nbwA:
undetectable		 2f162-1nbwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.19A 2f16N-1nbwA:
undetectable		 2f16N-1nbwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 TYR B  12
GLY B  20
ALA B  21
LEU B  25
 None
 0.84A 2wekB-1nbwB:
undetectable		 2wekB-1nbwB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 SER A 543
GLU A 429
ASP A 550
 None
 0.78A 2zthA-1nbwA:
3.6		 2zthA-1nbwA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 THR A  37
ILE A  46
LEU A  50
VAL A 387
LEU A  72
 None
 1.05A 3a51A-1nbwA:
undetectable		 3a51A-1nbwA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  37
ILE A  46
LEU A  50
VAL A 387
LEU A  72
 None
 1.04A 3a51D-1nbwA:
0.0		 3a51D-1nbwA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 8 VAL A 359
GLY A 264
GLU A 302
GLY A 308
ALA A 307
 None
 1.15A 3aruA-1nbwA:
undetectable		 3aruA-1nbwA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 286
ALA A 289
ILE A 331
ARG A 315
LEU A 311
 None
 1.10A 3dauA-1nbwA:
undetectable		 3dauA-1nbwA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 VAL A  29
SER A  31
ILE A   7
THR A  13
ILE A  33
 None
 1.12A 3ddyA-1nbwA:
0.0		 3ddyA-1nbwA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 GLY A 351
ILE A  98
VAL A 187
GLN A 192
 None
 0.86A 3fi0E-1nbwA:
undetectable		 3fi0E-1nbwA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 LEU A 213
LEU A 190
LEU A 249
LEU A 150
 None
 0.74A 3g8iA-1nbwA:
0.0		 3g8iA-1nbwA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 LEU A 213
LEU A 249
ILE A  98
ALA A 162
ALA A 199
 None
 0.95A 3mdvB-1nbwA:
undetectable		 3mdvB-1nbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.19A 3mg02-1nbwA:
undetectable
3mg0V-1nbwA:
undetectable		 3mg02-1nbwA:
18.33
3mg0V-1nbwA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.16A 3mg0N-1nbwA:
undetectable		 3mg0N-1nbwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 GLU B  30
LEU A 172
LEU A 181
 None
 0.61A 3ohtA-1nbwB:
undetectable		 3ohtA-1nbwB:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 GLU B  30
LEU A 172
LEU A 181
 None
 0.63A 3ohtB-1nbwB:
undetectable		 3ohtB-1nbwB:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 ILE A 286
LEU A 334
GLU A  85
ALA A  83
 None
 0.79A 3r9sA-1nbwA:
undetectable		 3r9sA-1nbwA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 PRO A  61
THR A  60
LEU A   3
 None
 0.78A 3ttrA-1nbwA:
undetectable		 3ttrA-1nbwA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 TYR A 217
ILE A 219
SER A 226
ILE A 233
ALA A 237
 None
 1.22A 3u6tA-1nbwA:
undetectable		 3u6tA-1nbwA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 SER A 561
ASP A 422
ASP A 333
 None
 0.90A 3uj7A-1nbwA:
undetectable		 3uj7A-1nbwA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 VAL B  34
GLY B 105
HIS B  76
SER B  58
PRO B   6
 None
 1.33A 4bvaA-1nbwB:
undetectable		 4bvaA-1nbwB:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 VAL B  34
GLY B 105
HIS B  76
SER B  58
PRO B   6
 None
 1.28A 4bvaB-1nbwB:
undetectable		 4bvaB-1nbwB:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 ILE A 286
LEU A 266
ALA A 336
VAL A 337
 None
 0.66A 4g77A-1nbwA:
undetectable		 4g77A-1nbwA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ILE A 286
ALA A 289
ILE A 331
ARG A 315
LEU A 311
 None
 1.09A 4kjkA-1nbwA:
undetectable		 4kjkA-1nbwA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 ALA A 581
ASP A 550
ILE A 551
ILE A 425
 None
 0.81A 4kttB-1nbwA:
undetectable		 4kttB-1nbwA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 ALA A 581
ASP A 550
ILE A 551
ILE A 425
 None
 0.72A 4kttD-1nbwA:
undetectable		 4kttD-1nbwA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 SER A 245
HIS A 100
ILE A 164
GLU A 352
 None
 1.35A 4ms4A-1nbwA:
undetectable		 4ms4A-1nbwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 SER A 561
ASP A 422
ASP A 333
 None
 0.88A 4mwzA-1nbwA:
undetectable		 4mwzA-1nbwA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 GLY A 170
ASP A 168
ILE A 164
VAL A 201
ILE A 134
 None
 0.90A 4q5mA-1nbwA:
undetectable		 4q5mA-1nbwA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 GLY A 441
LYS A 464
GLY A 559
SER A 560
ILE A 566
 None
 0.75A 5aqfA-1nbwA:
15.4		 5aqfA-1nbwA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 GLY A 441
LYS A 464
GLY A 559
SER A 560
ILE A 566
 None
 0.74A 5aqfC-1nbwA:
9.4		 5aqfC-1nbwA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 GLY A 441
LYS A 464
GLY A 559
SER A 560
ILE A 566
 None
 0.70A 5aqyA-1nbwA:
14.8		 5aqyA-1nbwA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 SER B  58
GLN B  37
ALA B  52
GLY B  51
THR B  75
 None
 1.22A 5bxnH-1nbwB:
undetectable
5bxnI-1nbwB:
undetectable		 5bxnH-1nbwB:
21.08
5bxnI-1nbwB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 SER B 114
ALA B 104
GLY B 105
ALA B 102
ASP A 168
 None
 1.33A 5bxnV-1nbwB:
undetectable
5bxnW-1nbwB:
undetectable		 5bxnV-1nbwB:
21.08
5bxnW-1nbwB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_A_ACRA1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 ASN A 481
GLU A 480
PRO A 567
GLU A 565
ARG A 523
 None
 1.43A 5cltA-1nbwA:
0.9		 5cltA-1nbwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_B_ACRB1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 ASN A 481
GLU A 480
PRO A 567
GLU A 565
ARG A 523
 None
 1.46A 5cltB-1nbwA:
0.0		 5cltB-1nbwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_C_ACRC1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 ASN A 481
GLU A 480
PRO A 567
GLU A 565
ARG A 523
 None
 1.47A 5cltC-1nbwA:
2.1		 5cltC-1nbwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		5 / 12 THR A 104
GLY B  28
LEU B 100
LEU B  85
SER B 114
 None
 1.13A 5jglB-1nbwA:
undetectable		 5jglB-1nbwA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.18A 5l5zV-1nbwA:
undetectable
5l5zb-1nbwA:
undetectable		 5l5zV-1nbwA:
17.77
5l5zb-1nbwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 SER B 114
ALA B 104
GLY B 105
ALA B 102
ASP A 168
 None
 1.30A 5l5zH-1nbwB:
undetectable
5l5zI-1nbwB:
undetectable		 5l5zH-1nbwB:
21.08
5l5zI-1nbwB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.18A 5l5zH-1nbwA:
undetectable
5l5zN-1nbwA:
undetectable		 5l5zH-1nbwA:
17.77
5l5zN-1nbwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
GLYCEROL DEHYDRATASE
REACTIVASE BETA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 SER B 114
ALA B 104
GLY B 105
ALA B 102
ASP A 168
 None
 1.29A 5l5zV-1nbwB:
undetectable
5l5zW-1nbwB:
undetectable		 5l5zV-1nbwB:
21.08
5l5zW-1nbwB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 8 ILE A 425
ALA A 424
VAL A 555
PHE A 553
VAL A 554
 None
 1.05A 5l94A-1nbwA:
undetectable		 5l94A-1nbwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.15A 5lf3b-1nbwA:
undetectable		 5lf3b-1nbwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.15A 5lf3N-1nbwA:
undetectable		 5lf3N-1nbwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.18A 5lf7V-1nbwA:
undetectable
5lf7b-1nbwA:
undetectable		 5lf7V-1nbwA:
17.58
5lf7b-1nbwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 THR A  14
THR A  13
SER A  31
GLY A  32
ALA A  52
 None
 1.18A 5lf7H-1nbwA:
undetectable
5lf7N-1nbwA:
undetectable		 5lf7H-1nbwA:
17.58
5lf7N-1nbwA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 ILE A 432
ALA A 394
ALA A 412
ILE A 413
ILE A 551
 None
 0.91A 5mvmD-1nbwA:
0.0
5mvmE-1nbwA:
0.0		 5mvmD-1nbwA:
8.64
5mvmE-1nbwA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 GLU A  85
MET A 310
LEU A 266
ILE A 286
 None
 0.94A 5mzjA-1nbwA:
0.0		 5mzjA-1nbwA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ASP A   8
VAL A 389
ALA A 424
GLN A 373
LEU A 370
 None
 1.28A 5tudD-1nbwA:
undetectable		 5tudD-1nbwA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 LEU A 311
ILE A 268
LEU A 437
ALA A 438
 None
 0.83A 5y7pC-1nbwA:
0.0		 5y7pC-1nbwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		6 / 12 GLY A 417
GLU A 461
GLY A 441
LEU A 562
GLY A 559
GLY A 558
 None
 1.25A 5zhmB-1nbwA:
undetectable		 5zhmB-1nbwA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		6 / 12 LEU A 556
GLY A 584
GLY A 591
SER A 560
ILE A 566
PRO A 567
 None
 1.40A 5zhmB-1nbwA:
undetectable		 5zhmB-1nbwA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 ALA A 581
ASP A 550
ILE A 551
ILE A 425
 None
 0.84A 6fbnA-1nbwA:
undetectable		 6fbnA-1nbwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 4 ALA A 394
ALA A 397
ALA A 424
ALA A 434
 None
 0.68A 6gtqA-1nbwA:
0.4
6gtqB-1nbwA:
0.4		 6gtqA-1nbwA:
15.32
6gtqB-1nbwA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1nbw GLYCEROL DEHYDRATASE
REACTIVASE ALPHA
SUBUNIT
(Klebsiella
pneumoniae) 		4 / 4 ALA A 424
ALA A 434
ALA A 394
ALA A 397
 None
 0.68A 6gtqA-1nbwA:
0.4
6gtqB-1nbwA:
0.4		 6gtqA-1nbwA:
15.32
6gtqB-1nbwA:
15.32