SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1nc7 HYPOTHETICAL PROTEIN
TM1070
(Thermotoga
maritima) 		4 / 7 PHE A   9
PRO A  10
ASP A  11
THR A 108
 None
 0.99A 2aouB-1nc7A:
undetectable		 2aouB-1nc7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1nc7 HYPOTHETICAL PROTEIN
TM1070
(Thermotoga
maritima) 		4 / 5 ILE A 109
THR A 108
THR A 107
PHE A   9
 None
 0.88A 3snfA-1nc7A:
undetectable		 3snfA-1nc7A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nc7 HYPOTHETICAL PROTEIN
TM1070
(Thermotoga
maritima) 		4 / 7 ILE A  42
PHE A  44
ARG A  67
LEU A  93
 None
 0.86A 5b1bN-1nc7A:
undetectable
5b1bW-1nc7A:
undetectable		 5b1bN-1nc7A:
13.09
5b1bW-1nc7A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nc7 HYPOTHETICAL PROTEIN
TM1070
(Thermotoga
maritima) 		4 / 8 ILE A  42
PHE A  44
ARG A  67
LEU A  93
 None
 0.94A 5zcqN-1nc7A:
undetectable
5zcqW-1nc7A:
0.0		 5zcqN-1nc7A:
13.09
5zcqW-1nc7A:
14.71