SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ncb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 LYS H 221
TYR H 122
PRO H 123
 None
 1.43A 2j9cC-1ncbH:
undetectable		 2j9cC-1ncbH:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H 116
SER H 216
LYS H 218
 None
 0.87A 3aocC-1ncbH:
undetectable		 3aocC-1ncbH:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)
(Mus
musculus) 		4 / 4 ILE H  82
LEU H  80
LYS H  19
ASN H  82
 None
 1.35A 4g19D-1ncbH:
0.0		 4g19D-1ncbH:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 GLU H  96
TRP H  50
ASN H  31
 None
 0.92A 5dv4A-1ncbH:
undetectable		 5dv4A-1ncbH:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)
(Mus
musculus) 		4 / 5 GLU H 150
PHE H 148
HIS H 212
THR H 110
 None
 1.04A 6b58A-1ncbH:
0.3		 6b58A-1ncbH:
17.22