SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nd4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 ALA A  35
VAL A  49
TRP A  24
 None
 0.88A 1av2C-1nd4A:
undetectable
1av2D-1nd4A:
undetectable		 1av2C-1nd4A:
5.86
1av2D-1nd4A:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		4 / 7 PHE A 240
ALA A 224
ILE A 246
ILE A 254
 None
 0.84A 1oniD-1nd4A:
1.9
1oniF-1nd4A:
1.9		 1oniD-1nd4A:
17.06
1oniF-1nd4A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QYX_A_ASDA500_1
(ESTRADIOL 17
BETA-DEHYDROGENASE 1)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 VAL A  75
LEU A 126
HIS A 124
PHE A 206
VAL A 185
 None
 1.25A 1qyxA-1nd4A:
0.3		 1qyxA-1nd4A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 ALA A  35
VAL A  49
TRP A  24
 None
 0.86A 1w5uC-1nd4A:
undetectable
1w5uD-1nd4A:
undetectable		 1w5uC-1nd4A:
5.86
1w5uD-1nd4A:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 SER A  68
THR A  73
PHE A 203
 None
 0.77A 2x91A-1nd4A:
0.0		 2x91A-1nd4A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 GLU A 182
HIS A 135
HIS A 139
 None
 0.94A 3co4A-1nd4A:
undetectable		 3co4A-1nd4A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		4 / 5 LEU A 103
SER A 105
LEU A 193
PRO A 194
 None
 1.37A 3onnA-1nd4A:
0.0		 3onnA-1nd4A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 12 HIS A 188
LEU A 212
GLY A 210
ALA A 144
LEU A 260
 None
 1.01A 3vywC-1nd4A:
undetectable		 3vywC-1nd4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 LEU A  60
LEU A  92
ASP A 190
ASN A 195
ASP A 208
GLY A 210
 None
None
KAN  A1300 ( 2.8A)
MG  A 400 (-2.7A)
MG  A 400 (-3.2A)
None
 1.29A 4an2A-1nd4A:
7.0		 4an2A-1nd4A:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.58A 4feuA-1nd4A:
31.5
4feuB-1nd4A:
30.1		 4feuA-1nd4A:
33.94
4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 12 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.87A 4feuA-1nd4A:
31.5
4feuB-1nd4A:
30.1		 4feuA-1nd4A:
33.94
4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.27A 4feuB-1nd4A:
30.1		 4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.89A 4feuB-1nd4A:
30.1		 4feuB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.64A 4feuC-1nd4A:
31.9		 4feuC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.77A 4feuD-1nd4A:
30.6		 4feuD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4feuB-1nd4A:
30.1
4feuE-1nd4A:
32.0		 4feuB-1nd4A:
33.94
4feuE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4feuF-1nd4A:
30.4		 4feuF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.83A 4feuF-1nd4A:
30.4		 4feuF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4fevA-1nd4A:
31.9		 4fevA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 7 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.76A 4fevB-1nd4A:
30.5		 4fevB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.66A 4fevC-1nd4A:
32.2
4fevD-1nd4A:
31.6
4fevE-1nd4A:
31.1		 4fevC-1nd4A:
33.94
4fevD-1nd4A:
33.94
4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4fevD-1nd4A:
31.6		 4fevD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4fevD-1nd4A:
31.6		 4fevD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4fevE-1nd4A:
31.1		 4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4fevE-1nd4A:
31.1		 4fevE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4fevF-1nd4A:
30.9		 4fevF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.84A 4fevF-1nd4A:
30.9		 4fevF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4fewA-1nd4A:
32.2
4fewD-1nd4A:
31.8		 4fewA-1nd4A:
33.94
4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.97A 4fewA-1nd4A:
32.2
4fewD-1nd4A:
31.8		 4fewA-1nd4A:
33.94
4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fewB-1nd4A:
31.5		 4fewB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.79A 4fewB-1nd4A:
31.5		 4fewB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.33A 4fewC-1nd4A:
32.2
4fewD-1nd4A:
31.8
4fewF-1nd4A:
31.4		 4fewC-1nd4A:
33.94
4fewD-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4fewD-1nd4A:
31.8		 4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4fewD-1nd4A:
31.8		 4fewD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fewE-1nd4A:
31.6
4fewF-1nd4A:
31.4		 4fewE-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.94A 4fewE-1nd4A:
31.6
4fewF-1nd4A:
31.4		 4fewE-1nd4A:
33.94
4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.25A 4fewF-1nd4A:
31.4		 4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.86A 4fewF-1nd4A:
31.4		 4fewF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.35A 4fexA-1nd4A:
31.7
4fexB-1nd4A:
30.9		 4fexA-1nd4A:
33.94
4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.95A 4fexA-1nd4A:
31.7
4fexB-1nd4A:
30.9		 4fexA-1nd4A:
33.94
4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4fexB-1nd4A:
30.9		 4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.80A 4fexB-1nd4A:
30.9		 4fexB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4fexA-1nd4A:
31.7
4fexC-1nd4A:
30.8		 4fexA-1nd4A:
33.94
4fexC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4fexA-1nd4A:
31.7
4fexC-1nd4A:
30.8		 4fexA-1nd4A:
33.94
4fexC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.95A 4fexD-1nd4A:
32.3		 4fexD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.35A 4fexD-1nd4A:
32.3		 4fexD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.37A 4fexE-1nd4A:
32.1		 4fexE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FEX_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.93A 4fexE-1nd4A:
32.1		 4fexE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkhA-1nd4A:
32.0
4gkhB-1nd4A:
31.3		 4gkhA-1nd4A:
33.94
4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkhB-1nd4A:
31.3		 4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.70A 4gkhB-1nd4A:
31.3		 4gkhB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhC-1nd4A:
32.0
4gkhD-1nd4A:
31.4		 4gkhC-1nd4A:
33.94
4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.97A 4gkhC-1nd4A:
32.0
4gkhD-1nd4A:
31.4		 4gkhC-1nd4A:
33.94
4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.75A 4gkhD-1nd4A:
31.4		 4gkhD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkhE-1nd4A:
31.6
4gkhF-1nd4A:
31.3		 4gkhE-1nd4A:
33.94
4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		4 / 8 ASP A 157
ASP A 159
ARG A 147
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
None
KAN  A1300 (-3.1A)
 1.16A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.51A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.86A 4gkhF-1nd4A:
31.5		 4gkhF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.28A 4gkhG-1nd4A:
30.6		 4gkhG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 7 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkhG-1nd4A:
30.6		 4gkhG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhG-1nd4A:
30.6
4gkhH-1nd4A:
31.7		 4gkhG-1nd4A:
33.94
4gkhH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.92A 4gkhG-1nd4A:
30.6
4gkhH-1nd4A:
31.7		 4gkhG-1nd4A:
33.94
4gkhH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4gkhI-1nd4A:
31.8
4gkhJ-1nd4A:
31.4		 4gkhI-1nd4A:
33.94
4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkhI-1nd4A:
31.8
4gkhJ-1nd4A:
31.4		 4gkhI-1nd4A:
33.94
4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 6 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkhJ-1nd4A:
31.4		 4gkhJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.27A 4gkhC-1nd4A:
32.0
4gkhK-1nd4A:
30.8		 4gkhC-1nd4A:
33.94
4gkhK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.83A 4gkhC-1nd4A:
32.0
4gkhK-1nd4A:
30.8		 4gkhC-1nd4A:
33.94
4gkhK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4gkhK-1nd4A:
30.8
4gkhL-1nd4A:
31.4		 4gkhK-1nd4A:
33.94
4gkhL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.96A 4gkhK-1nd4A:
30.8
4gkhL-1nd4A:
31.4		 4gkhK-1nd4A:
33.94
4gkhL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkiA-1nd4A:
31.4		 4gkiA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkiA-1nd4A:
31.4		 4gkiA-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkiA-1nd4A:
31.6
4gkiB-1nd4A:
31.9		 4gkiA-1nd4A:
33.94
4gkiB-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 8 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.65A 4gkiC-1nd4A:
31.0		 4gkiC-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.32A 4gkiC-1nd4A:
31.0
4gkiD-1nd4A:
31.6		 4gkiC-1nd4A:
33.94
4gkiD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4gkiC-1nd4A:
31.0
4gkiD-1nd4A:
31.6		 4gkiC-1nd4A:
33.94
4gkiD-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		7 / 10 ASP A 157
ASP A 159
ASP A 190
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.34A 4gkiE-1nd4A:
31.5		 4gkiE-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.75A 4gkiF-1nd4A:
31.7		 4gkiF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 1.47A 4gkiF-1nd4A:
31.7		 4gkiF-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.26A 4gkiE-1nd4A:
31.5
4gkiG-1nd4A:
31.2		 4gkiE-1nd4A:
33.94
4gkiG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 8 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.87A 4gkiE-1nd4A:
31.5
4gkiG-1nd4A:
31.2		 4gkiE-1nd4A:
33.94
4gkiG-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.33A 4gkiG-1nd4A:
31.2
4gkiH-1nd4A:
31.5		 4gkiG-1nd4A:
33.94
4gkiH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 10 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.94A 4gkiG-1nd4A:
31.2
4gkiH-1nd4A:
31.5		 4gkiG-1nd4A:
33.94
4gkiH-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 11 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.29A 4gkiI-1nd4A:
32.2
4gkiJ-1nd4A:
31.7		 4gkiI-1nd4A:
33.94
4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 9 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.40A 4gkiJ-1nd4A:
31.7		 4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.85A 4gkiJ-1nd4A:
31.7		 4gkiJ-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
ASP A 190
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.30A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 157
ASP A 159
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.91A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 9 ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 1.48A 4gkiK-1nd4A:
31.7		 4gkiK-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ARG A 211
GLU A 230
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 (-2.6A)
KAN  A1300 (-4.1A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.90A 4gkiK-1nd4A:
31.7
4gkiL-1nd4A:
31.9		 4gkiK-1nd4A:
33.94
4gkiL-1nd4A:
33.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		6 / 12 ASP A 157
ASP A 159
ASP A 190
ARG A 211
ASP A 261
GLU A 262
 KAN  A1300 (-3.7A)
KAN  A1300 (-3.2A)
KAN  A1300 ( 2.8A)
KAN  A1300 (-2.6A)
KAN  A1300 (-3.8A)
KAN  A1300 (-3.1A)
 0.31A 4gkiK-1nd4A:
31.7
4gkiL-1nd4A:
31.9		 4gkiK-1nd4A:
33.94
4gkiL-1nd4A:
33.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 LEU A 241
ASP A 227
ALA A 237
VAL A 113
ILE A 196
 None
KAN  A1300 (-3.8A)
None
None
None
 1.23A 4uuuA-1nd4A:
0.0
4uuuB-1nd4A:
0.0		 4uuuA-1nd4A:
23.81
4uuuB-1nd4A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		5 / 11 LEU A 241
ASP A 227
ALA A 237
VAL A 113
ILE A 196
 None
KAN  A1300 (-3.8A)
None
None
None
 1.23A 4uuuB-1nd4A:
undetectable		 4uuuB-1nd4A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 ASP A 216
ARG A 217
TYR A 218
 None
 1.02A 5a7mA-1nd4A:
undetectable		 5a7mA-1nd4A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		3 / 3 ASP A 216
ARG A 217
TYR A 218
 None
 1.02A 5a7mB-1nd4A:
undetectable		 5a7mB-1nd4A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E
(Klebsiella
pneumoniae) 		4 / 5 LEU A 126
ARG A 122
PHE A 206
LEU A  70
 None
 1.19A 5m10A-1nd4A:
undetectable		 5m10A-1nd4A:
20.30