SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ndf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 6 TRP A 102
LEU A  98
LEU A  38
PRO A  39
152  A5001 (-4.7A)
None
None
None
1.34A 1hz4A-1ndfA:
undetectable
1hz4A-1ndfA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
3 / 3 ILE A 351
LEU A 354
VAL A 358
None
0.49A 1mz9B-1ndfA:
undetectable
1mz9B-1ndfA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 ILE A 116
GLY A 567
GLY A 575
ILE A 409
PRO A 120
None
0.99A 1nv8B-1ndfA:
2.1
1nv8B-1ndfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 ILE A 116
GLY A 567
GLY A 575
ILE A 409
PRO A 120
None
0.99A 1sg9B-1ndfA:
undetectable
1sg9B-1ndfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.99A 1v55C-1ndfA:
1.3
1v55N-1ndfA:
0.0
1v55P-1ndfA:
1.4
1v55C-1ndfA:
17.22
1v55N-1ndfA:
20.15
1v55P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 ILE A 116
GLY A 567
GLY A 575
ILE A 409
PRO A 120
None
1.02A 1vq1B-1ndfA:
2.1
1vq1B-1ndfA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 ILE A 433
ALA A 436
ILE A 576
LEU A 611
ALA A 610
None
0.89A 2aclG-1ndfA:
undetectable
2aclG-1ndfA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 6 TYR A  50
SER A 470
GLN A 438
ASP A 466
None
1.35A 2cl5B-1ndfA:
0.0
2cl5B-1ndfA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 5 LEU A 551
GLY A 573
PRO A 568
ILE A 576
None
0.83A 2q9rA-1ndfA:
undetectable
2q9rA-1ndfA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 5 GLU A 347
PRO A 350
ILE A 351
GLY A 348
152  A5001 (-4.0A)
None
None
None
1.07A 2qeuA-1ndfA:
0.0
2qeuC-1ndfA:
0.0
2qeuA-1ndfA:
11.54
2qeuC-1ndfA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.96A 2y69C-1ndfA:
1.4
2y69N-1ndfA:
0.0
2y69P-1ndfA:
1.3
2y69C-1ndfA:
17.22
2y69N-1ndfA:
20.15
2y69P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 5 TYR A 578
ILE A 585
LEU A 412
LEU A 607
None
1.13A 2zb7A-1ndfA:
undetectable
2zb7A-1ndfA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 6 TYR A  50
SER A 470
GLN A 438
ASP A 466
None
1.39A 2zvjA-1ndfA:
0.0
2zvjA-1ndfA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.09A 3ablA-1ndfA:
2.7
3ablC-1ndfA:
1.3
3ablP-1ndfA:
1.4
3ablA-1ndfA:
20.15
3ablC-1ndfA:
17.22
3ablP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.06A 3ablC-1ndfA:
1.1
3ablN-1ndfA:
0.0
3ablP-1ndfA:
1.4
3ablC-1ndfA:
17.22
3ablN-1ndfA:
20.15
3ablP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.99A 3abmA-1ndfA:
2.8
3abmC-1ndfA:
1.3
3abmP-1ndfA:
1.3
3abmA-1ndfA:
20.15
3abmC-1ndfA:
17.22
3abmP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.01A 3asnC-1ndfA:
1.3
3asnN-1ndfA:
0.0
3asnP-1ndfA:
1.3
3asnC-1ndfA:
17.22
3asnN-1ndfA:
20.15
3asnP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.01A 3asoA-1ndfA:
0.2
3asoC-1ndfA:
1.3
3asoP-1ndfA:
undetectable
3asoA-1ndfA:
20.15
3asoC-1ndfA:
17.22
3asoP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.99A 3asoC-1ndfA:
1.3
3asoN-1ndfA:
0.0
3asoP-1ndfA:
1.4
3asoC-1ndfA:
17.22
3asoN-1ndfA:
20.15
3asoP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 5 VAL A 114
GLN A 328
PHE A 566
ARG A 256
None
None
152  A5001 (-3.3A)
None
1.09A 3bjwE-1ndfA:
0.0
3bjwE-1ndfA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 6 VAL A 114
GLN A 328
PHE A 566
ARG A 256
None
None
152  A5001 (-3.3A)
None
1.19A 3bjwF-1ndfA:
0.0
3bjwF-1ndfA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 5 TYR A 442
ALA A 499
ALA A 610
MET A 603
None
1.15A 3d91A-1ndfA:
0.0
3d91A-1ndfA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 GLY A  86
GLY A 522
LEU A 520
GLU A 529
ALA A 527
None
0.87A 3kkzB-1ndfA:
undetectable
3kkzB-1ndfA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 SER A 282
ILE A 330
ASP A 289
LEU A 288
LEU A 214
None
1.20A 3lcvB-1ndfA:
undetectable
3lcvB-1ndfA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 GLY A 121
VAL A 352
THR A 553
ILE A 576
PHE A 566
None
None
None
None
152  A5001 (-3.3A)
1.31A 3mnpA-1ndfA:
undetectable
3mnpA-1ndfA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 ASN A 320
ILE A 330
GLN A 328
PHE A 323
None
1.03A 3tvxB-1ndfA:
undetectable
3tvxB-1ndfA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.96A 3wg7A-1ndfA:
0.0
3wg7C-1ndfA:
1.3
3wg7P-1ndfA:
1.3
3wg7A-1ndfA:
20.15
3wg7C-1ndfA:
17.22
3wg7P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.95A 3wg7C-1ndfA:
1.3
3wg7N-1ndfA:
0.0
3wg7P-1ndfA:
1.3
3wg7C-1ndfA:
17.22
3wg7N-1ndfA:
20.15
3wg7P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.98A 3x2qA-1ndfA:
2.7
3x2qC-1ndfA:
1.3
3x2qP-1ndfA:
1.4
3x2qA-1ndfA:
20.15
3x2qC-1ndfA:
17.22
3x2qP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.99A 3x2qC-1ndfA:
1.3
3x2qN-1ndfA:
0.5
3x2qP-1ndfA:
1.4
3x2qC-1ndfA:
17.22
3x2qN-1ndfA:
20.15
3x2qP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 PHE A 421
PRO A 422
PRO A 580
GLN A 434
ALA A 436
None
1.48A 4a84A-1ndfA:
0.0
4a84A-1ndfA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 4 LEU A 457
LEU A 462
GLN A 166
GLU A 161
None
1.27A 4i41A-1ndfA:
undetectable
4i41A-1ndfA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.97A 5b1aA-1ndfA:
0.2
5b1aC-1ndfA:
1.0
5b1aP-1ndfA:
1.3
5b1aA-1ndfA:
20.15
5b1aC-1ndfA:
17.22
5b1aP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.12A 5b1bA-1ndfA:
undetectable
5b1bC-1ndfA:
1.3
5b1bP-1ndfA:
1.3
5b1bA-1ndfA:
20.15
5b1bC-1ndfA:
17.22
5b1bP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.95A 5b3sA-1ndfA:
0.3
5b3sC-1ndfA:
1.4
5b3sP-1ndfA:
1.3
5b3sA-1ndfA:
20.15
5b3sC-1ndfA:
17.22
5b3sP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 PRO A 376
LEU A 375
LEU A 381
LYS A 235
GLU A 213
None
1.35A 5emlA-1ndfA:
undetectable
5emlA-1ndfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 ILE A 279
GLY A 249
THR A 252
ASN A 320
None
0.93A 5hwaA-1ndfA:
0.0
5hwaA-1ndfA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.98A 5iy5C-1ndfA:
1.3
5iy5N-1ndfA:
0.2
5iy5P-1ndfA:
1.3
5iy5C-1ndfA:
17.59
5iy5N-1ndfA:
20.15
5iy5P-1ndfA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 10 ALA A 455
THR A 465
GLY A 513
ALA A 515
ASP A 517
None
152  A5001 (-2.8A)
None
None
None
1.46A 5l66K-1ndfA:
undetectable
5l66L-1ndfA:
undetectable
5l66K-1ndfA:
17.76
5l66L-1ndfA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 10 ALA A 455
THR A 465
GLY A 513
ALA A 515
ASP A 517
None
152  A5001 (-2.8A)
None
None
None
1.46A 5l66Y-1ndfA:
undetectable
5l66Z-1ndfA:
undetectable
5l66Y-1ndfA:
17.76
5l66Z-1ndfA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
3 / 3 ARG A 137
PHE A 329
LEU A 288
None
0.51A 5veuA-1ndfA:
undetectable
5veuA-1ndfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.90A 5w97A-1ndfA:
undetectable
5w97C-1ndfA:
1.4
5w97c-1ndfA:
1.4
5w97A-1ndfA:
20.15
5w97C-1ndfA:
17.22
5w97c-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.95A 5w97C-1ndfA:
1.4
5w97a-1ndfA:
undetectable
5w97c-1ndfA:
1.4
5w97C-1ndfA:
17.22
5w97a-1ndfA:
20.15
5w97c-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.96A 5wauA-1ndfA:
0.2
5wauC-1ndfA:
1.3
5wauc-1ndfA:
1.3
5wauA-1ndfA:
20.15
5wauC-1ndfA:
17.22
5wauc-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.97A 5wauC-1ndfA:
1.3
5waua-1ndfA:
0.2
5wauc-1ndfA:
1.3
5wauC-1ndfA:
17.22
5waua-1ndfA:
20.15
5wauc-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.02A 5x19A-1ndfA:
0.0
5x19C-1ndfA:
1.3
5x19P-1ndfA:
1.4
5x19A-1ndfA:
20.15
5x19C-1ndfA:
17.22
5x19P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.11A 5x1bA-1ndfA:
0.0
5x1bC-1ndfA:
1.4
5x1bP-1ndfA:
1.4
5x1bA-1ndfA:
20.15
5x1bC-1ndfA:
17.22
5x1bP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.99A 5x1fA-1ndfA:
0.0
5x1fC-1ndfA:
1.3
5x1fP-1ndfA:
1.4
5x1fA-1ndfA:
20.15
5x1fC-1ndfA:
17.22
5x1fP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.97A 5xdqA-1ndfA:
0.0
5xdqC-1ndfA:
1.4
5xdqP-1ndfA:
1.4
5xdqA-1ndfA:
20.15
5xdqC-1ndfA:
17.22
5xdqP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.99A 5xdqC-1ndfA:
1.4
5xdqN-1ndfA:
0.0
5xdqP-1ndfA:
1.4
5xdqC-1ndfA:
17.22
5xdqN-1ndfA:
20.15
5xdqP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.01A 5xdxC-1ndfA:
1.3
5xdxN-1ndfA:
2.8
5xdxP-1ndfA:
1.4
5xdxC-1ndfA:
17.56
5xdxN-1ndfA:
20.15
5xdxP-1ndfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.95A 5z84A-1ndfA:
0.0
5z84C-1ndfA:
1.4
5z84P-1ndfA:
1.3
5z84A-1ndfA:
20.15
5z84C-1ndfA:
17.22
5z84P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.01A 5z84C-1ndfA:
1.4
5z84N-1ndfA:
0.2
5z84P-1ndfA:
1.3
5z84C-1ndfA:
17.22
5z84N-1ndfA:
20.15
5z84P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.94A 5z85A-1ndfA:
0.0
5z85C-1ndfA:
1.3
5z85P-1ndfA:
1.3
5z85A-1ndfA:
20.15
5z85C-1ndfA:
17.22
5z85P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.98A 5z85C-1ndfA:
1.3
5z85N-1ndfA:
0.0
5z85P-1ndfA:
1.3
5z85C-1ndfA:
17.22
5z85N-1ndfA:
20.15
5z85P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.94A 5z86A-1ndfA:
2.8
5z86C-1ndfA:
1.3
5z86P-1ndfA:
1.3
5z86A-1ndfA:
20.15
5z86C-1ndfA:
17.22
5z86P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.00A 5z86C-1ndfA:
1.3
5z86N-1ndfA:
0.2
5z86P-1ndfA:
1.3
5z86C-1ndfA:
17.22
5z86N-1ndfA:
20.15
5z86P-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.94A 5zcoA-1ndfA:
0.0
5zcoC-1ndfA:
1.3
5zcoP-1ndfA:
1.4
5zcoA-1ndfA:
20.15
5zcoC-1ndfA:
17.22
5zcoP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.98A 5zcoC-1ndfA:
1.3
5zcoN-1ndfA:
0.3
5zcoP-1ndfA:
1.4
5zcoC-1ndfA:
17.22
5zcoN-1ndfA:
20.15
5zcoP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.96A 5zcpA-1ndfA:
2.7
5zcpC-1ndfA:
1.3
5zcpP-1ndfA:
1.3
5zcpA-1ndfA:
20.15
5zcpC-1ndfA:
17.22
5zcpP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
0.99A 5zcpC-1ndfA:
1.3
5zcpN-1ndfA:
0.2
5zcpP-1ndfA:
1.3
5zcpC-1ndfA:
17.22
5zcpN-1ndfA:
20.15
5zcpP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
0.95A 5zcqA-1ndfA:
0.3
5zcqC-1ndfA:
1.4
5zcqP-1ndfA:
1.3
5zcqA-1ndfA:
20.15
5zcqC-1ndfA:
17.22
5zcqP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 VAL A 271
SER A 278
TRP A 322
ASN A 272
VAL A 248
None
1.34A 6a94A-1ndfA:
undetectable
6a94A-1ndfA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
3 / 3 GLY A 513
ASP A 466
ILE A 468
None
0.59A 6dgxB-1ndfA:
undetectable
6dgxB-1ndfA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
5 / 12 VAL A 216
TYR A 361
ILE A 229
PHE A 284
PHE A 329
None
1.43A 6j20A-1ndfA:
0.4
6j20A-1ndfA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 8 LEU A  38
HIS A 343
ASP A 466
THR A 465
None
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
1.06A 6nknC-1ndfA:
1.4
6nknN-1ndfA:
0.0
6nknP-1ndfA:
1.3
6nknC-1ndfA:
17.22
6nknN-1ndfA:
20.15
6nknP-1ndfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus
musculus)
4 / 7 HIS A 343
ASP A 466
THR A 465
LEU A  38
152  A5001 (-3.9A)
None
152  A5001 (-2.8A)
None
1.10A 6nmfA-1ndfA:
2.7
6nmfC-1ndfA:
0.8
6nmfP-1ndfA:
1.4
6nmfA-1ndfA:
20.15
6nmfC-1ndfA:
17.22
6nmfP-1ndfA:
17.22