SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ndg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1ndg IMMUNOGLOBULIN GAMMA
1 CHAIN
(Mus
musculus) 		4 / 7 SER B 513
PRO B 511
ALA B 516
ALA B 418
 None
 1.00A 1k5qA-1ndgB:
undetectable
1k5qB-1ndgB:
undetectable		 1k5qA-1ndgB:
19.83
1k5qB-1ndgB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ndg IMMUNOGLOBULIN GAMMA
1 CHAIN
(Mus
musculus) 		3 / 3 THR B 410
GLU B 448
HIS B 510
 None
 0.83A 3g1uB-1ndgB:
undetectable		 3g1uB-1ndgB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1ndg IMMUNOGLOBULIN GAMMA
1 CHAIN
(Mus
musculus) 		4 / 4 TYR B 359
THR B 357
GLY B 349
LEU B 380
 None
 1.28A 4w5nA-1ndgB:
undetectable		 4w5nA-1ndgB:
12.43