SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nds'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.20A 1oe1A-1ndsA:
undetectable		 1oe1A-1ndsA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 5 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.19A 1oe2A-1ndsA:
undetectable		 1oe2A-1ndsA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.18A 1oe3A-1ndsA:
undetectable		 1oe3A-1ndsA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.63A 2fqdA-1ndsA:
undetectable		 2fqdA-1ndsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.61A 2fqeA-1ndsA:
undetectable		 2fqeA-1ndsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.61A 2fqfA-1ndsA:
undetectable		 2fqfA-1ndsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.62A 2fqgA-1ndsA:
undetectable		 2fqgA-1ndsA:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.20A 2xxgA-1ndsA:
undetectable		 2xxgA-1ndsA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 5 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.19A 2xxgC-1ndsA:
undetectable		 2xxgC-1ndsA:
75.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1nds NITRITE REDUCTASE
(Achromobacter
xylosoxidans) 		4 / 4 HIS A  95
CYH A 136
HIS A 145
MET A 150
 CU  A 501 ( 3.2A)
CU  A 501 ( 2.0A)
CU  A 501 ( 3.1A)
CU  A 501 ( 2.6A)
 0.60A 4ef3A-1ndsA:
undetectable		 4ef3A-1ndsA:
22.58