SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nez'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		5 / 12 GLY A 162
SER A 167
TYR A  59
LEU A   5
TYR A   7
 None
 1.45A 1fm6X-1nezA:
undetectable		 1fm6X-1nezA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		5 / 12 GLY A 162
SER A 167
TYR A  59
LEU A   5
TYR A   7
 None
 1.38A 1zgyA-1nezA:
0.0		 1zgyA-1nezA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		4 / 8 TYR A 152
TYR A  99
PHE A  73
SER A  69
 None
 1.06A 3jz0B-1nezA:
undetectable		 3jz0B-1nezA:
23.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		7 / 10 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.54A 3uprA-1nezA:
28.5		 3uprA-1nezA:
66.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		7 / 10 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.51A 3uprC-1nezA:
28.4		 3uprC-1nezA:
66.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		6 / 10 TYR A   9
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.35A 3vriA-1nezA:
28.4
3vriC-1nezA:
undetectable		 3vriA-1nezA:
66.79
3vriC-1nezA:
3.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		7 / 12 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.51A 3vrjA-1nezA:
28.4
3vrjC-1nezA:
undetectable		 3vrjA-1nezA:
66.79
3vrjC-1nezA:
3.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		5 / 12 GLY A 162
SER A 167
TYR A  59
LEU A   5
TYR A   7
 None
 1.36A 4emaA-1nezA:
0.0		 4emaA-1nezA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		5 / 12 GLY A 162
SER A 167
TYR A  59
LEU A   5
TYR A   7
 None
 1.42A 4xldA-1nezA:
0.0		 4xldA-1nezA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		4 / 8 TRP A 133
TYR A 123
PHE A  73
TYR A 152
 None
 1.36A 5oajD-1nezA:
0.0
5oajE-1nezA:
0.0		 5oajD-1nezA:
21.75
5oajE-1nezA:
21.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		7 / 10 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.52A 5u98A-1nezA:
28.6		 5u98A-1nezA:
66.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN
(Mus
musculus) 		7 / 10 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.50A 5u98D-1nezA:
28.6		 5u98D-1nezA:
66.79