SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHQ_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1nf3	PAR-6B (Mus musculus)	5 / 8	THR C 206 GLY C 207 GLY C 170 LEU C 202 GLY C 201	THR C 206 ( 0.8A) GLY C 207 ( 0.0A) GLY C 170 ( 0.0A) LEU C 202 ( 0.6A) GLY C 201 ( 0.0A)	1.49A	1jhqA-1nf3C: undetectable	1jhqA-1nf3C: 14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHV_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1nf3	PAR-6B (Mus musculus)	5 / 8	THR C 206 GLY C 207 GLY C 170 LEU C 202 GLY C 201	THR C 206 ( 0.8A) GLY C 207 ( 0.0A) GLY C 170 ( 0.0A) LEU C 202 ( 0.6A) GLY C 201 ( 0.0A)	1.47A	1jhvA-1nf3C: undetectable	1jhvA-1nf3C: 14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR)	1nf3	PAR-6B (Mus musculus)	5 / 12	LEU C 216 VAL C 246 SER C 178 VAL C 231 LEU C 242	LEU C 216 ( 0.6A) VAL C 246 ( 0.6A) SER C 178 ( 0.0A) VAL C 231 ( 0.6A) LEU C 242 ( 0.6A)	1.17A	2hc4A-1nf3C: undetectable	2hc4A-1nf3C: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZLC_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1nf3	PAR-6B (Mus musculus)	5 / 12	LEU C 216 VAL C 246 SER C 178 VAL C 231 LEU C 242	LEU C 216 ( 0.6A) VAL C 246 ( 0.6A) SER C 178 ( 0.0A) VAL C 231 ( 0.6A) LEU C 242 ( 0.6A)	1.32A	2zlcA-1nf3C: undetectable	2zlcA-1nf3C: 20.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JHQ_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","1nf3","PAR-6B","Mus musculus",5,"THR C 206;GLY C 207;GLY C 170;LEU C 202;GLY C 201","THR C 206 ( 0.8A);GLY C 207 ( 0.0A);GLY C 170 ( 0.0A);LEU C 202 ( 0.6A);GLY C 201 ( 0.0A)","1.49A","1jhqA-1nf3C:undetectable","1jhqA-1nf3C:14.24"],["1JHV_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","1nf3","PAR-6B","Mus musculus",5,"THR C 206;GLY C 207;GLY C 170;LEU C 202;GLY C 201","THR C 206 ( 0.8A);GLY C 207 ( 0.0A);GLY C 170 ( 0.0A);LEU C 202 ( 0.6A);GLY C 201 ( 0.0A)","1.47A","1jhvA-1nf3C:undetectable","1jhvA-1nf3C:14.24"],["2HC4_A_VDXA525_1","VITAMIN D RECEPTOR","1nf3","PAR-6B","Mus musculus",5,"LEU C 216;VAL C 246;SER C 178;VAL C 231;LEU C 242","LEU C 216 ( 0.6A);VAL C 246 ( 0.6A);SER C 178 ( 0.0A);VAL C 231 ( 0.6A);LEU C 242 ( 0.6A)","1.17A","2hc4A-1nf3C:undetectable","2hc4A-1nf3C:18.33"],["2ZLC_A_VDXA500_1","VITAMIN D3 RECEPTOR","1nf3","PAR-6B","Mus musculus",5,"LEU C 216;VAL C 246;SER C 178;VAL C 231;LEU C 242","LEU C 216 ( 0.6A);VAL C 246 ( 0.6A);SER C 178 ( 0.0A);VAL C 231 ( 0.6A);LEU C 242 ( 0.6A)","1.32A","2zlcA-1nf3C:undetectable","2zlcA-1nf3C:20.70"]]