SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		5 / 8 ASP A  78
ASP A  57
ILE A  75
ILE A  55
GLY A  51
 None
 1.20A 1sh9A-1nf5A:
undetectable		 1sh9A-1nf5A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		5 / 10 ILE A  89
LEU A   3
ILE A  12
SER A  34
PHE A  53
 None
 1.09A 2w9sD-1nf5A:
undetectable		 2w9sD-1nf5A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		5 / 10 ILE A  89
LEU A   3
ILE A  12
SER A  34
PHE A  53
 None
 1.09A 2w9sF-1nf5A:
undetectable		 2w9sF-1nf5A:
17.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 7 GLN A  54
TRP A  60
ILE A  95
TRP A 104
 None
 0.41A 4ii8A-1nf5A:
21.1		 4ii8A-1nf5A:
34.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8A-1nf5A:
undetectable		 5hm8A-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8B-1nf5A:
undetectable		 5hm8B-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8C-1nf5A:
undetectable		 5hm8C-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8D-1nf5A:
undetectable		 5hm8D-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8E-1nf5A:
undetectable		 5hm8E-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8F-1nf5A:
undetectable		 5hm8F-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.22A 5hm8H-1nf5A:
undetectable		 5hm8H-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nf5 ALPHA-LACTALBUMIN
(Mus
musculus) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.18A 5utuH-1nf5A:
undetectable		 5utuH-1nf5A:
12.80